Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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Accurate RNA 5-methylcytosine site prediction based on heuristic physical-chemical properties reduction and classifier ensemble.

RNA 5-methylcytosine (mC) is an important post-transcriptional modification that plays an indispensa...

Apr 2018 29649472
Artificial neural network model for predicting the bioavailability of tacrolimus in patients with renal transplantation.

The objective of the current study was to explore the role of ABCB1 and CYP3A5 genetic polymorphisms...

Apr 2018 29621269
Prevalence and genotypes of Giardia lamblia from stray dogs and cats in Guangdong, China.

Giardia lamblia is a worldwide zoonotic intestinal parasite that infects humans and a wide range of ...

Apr 2018 31014884
Identification of Three Rheumatoid Arthritis Disease Subtypes by Machine Learning Integration of Synovial Histologic Features and RNA Sequencing Data.

OBJECTIVE: In this study, we sought to refine histologic scoring of rheumatoid arthritis (RA) synovi...

Apr 2018 29468833
Prediction of DNase I hypersensitive sites in plant genome using multiple modes of pseudo components.

DNase I hypersensitive sites (DHSs) are accessible chromatin zones hypersensitive to DNase I endonuc...

Mar 2018 29604265
Sequential regulatory activity prediction across chromosomes with convolutional neural networks.

Models for predicting phenotypic outcomes from genotypes have important applications to understandin...

Mar 2018 29588361
High-Order Convolutional Neural Network Architecture for Predicting DNA-Protein Binding Sites.

Although Deep learning algorithms have outperformed conventional methods in predicting the sequence ...

Mar 2018 29993783
Integrated optimization of unmanned aerial vehicle task allocation and path planning under steady wind.

Wind has a significant effect on the control of fixed-wing unmanned aerial vehicles (UAVs), resultin...

Mar 2018 29561888
A survey of recently emerged genome-wide computational enhancer predictor tools.

The race for the discovery of enhancers at a genome-wide scale has been on since the commencement of...

Mar 2018 29602043
Computational Prediction of Sigma-54 Promoters in Bacterial Genomes by Integrating Motif Finding and Machine Learning Strategies.

Sigma factor, as a unit of RNA polymerase holoenzyme, is a critical factor in the process of gene tr...

Mar 2018 29993815
Chromosome-wide gene dosage rebalance may benefit tumor progression.

The high-risk of tumor initiation in patients with Turner syndrome (TS) characterized by X chromosom...

Mar 2018 29546464
iRSpot-PDI: Identification of recombination spots by incorporating dinucleotide property diversity information into Chou's pseudo components.

Recombination spot identification plays an important role in revealing genome evolution and developi...

Mar 2018 29548799
Machine Learning of Partial Charges Derived from High-Quality Quantum-Mechanical Calculations.

Parametrization of small organic molecules for classical molecular dynamics simulations is not trivi...

Mar 2018 29461814
Brain-specific functional relationship networks inform autism spectrum disorder gene prediction.

Autism spectrum disorder (ASD) is a neuropsychiatric disorder with strong evidence of genetic contri...

Mar 2018 29507298
Probing light chain mutation effects on thrombin via molecular dynamics simulations and machine learning.

Thrombin is a key component for chemotherapeutic and antithrombotic therapy development. As the phys...

Mar 2018 29471734
Genes sharing the protein family domain decrease the performance of classification with RNA-seq genomic signatures.

BACKGROUND: The experience with running various types of classification on the CAMDA neuroblastoma d...

Feb 2018 29467011
Enhancing Hi-C data resolution with deep convolutional neural network HiCPlus.

Although Hi-C technology is one of the most popular tools for studying 3D genome organization, due t...

Feb 2018 29467363
Automated detection of preserved photoreceptor on optical coherence tomography in choroideremia based on machine learning.

Optical coherence tomography (OCT) can demonstrate early deterioration of the photoreceptor integrit...

Feb 2018 29341445
Identifying neuropsychiatric disorders using unsupervised clustering methods: Data and code.

This article provides data for five different neuropsychiatric disorders-Attention Deficit Hyperacti...

Feb 2018 30627610
GWAS-based machine learning approach to predict duloxetine response in major depressive disorder.

Major depressive disorder (MDD) is one of the most prevalent psychiatric disorders and is commonly t...

Feb 2018 29407288
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