Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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An outbreak of classical swine fever in pigs in Bangladesh, 2015.

In a group of 22 healthy pigs aged between 4 and 6 months, 2 pigs became ill with high fever, comple...

Nov 2017 29468080
A deep auto-encoder model for gene expression prediction.

BACKGROUND: Gene expression is a key intermediate level that genotypes lead to a particular trait. G...

Nov 2017 29219072
Cell cycle time series gene expression data encoded as cyclic attractors in Hopfield systems.

Modern time series gene expression and other omics data sets have enabled unprecedented resolution o...

Nov 2017 29149186
ATP-binding cassette transporter A1: A promising therapy target for prostate cancer.

ATP-binding cassette transporter A1 (ABCA1) has been found to mediate the transfer of cellular chole...

Nov 2017 29399345
PSCA rs1045531 Polymorphism and the Risk of Prostate Cancer in a Chinese Population Undergoing Prostate Biopsy.

BACKGROUND AND PURPOSE: This study explored the association between a single-nucleotide polymorphism...

Nov 2017 29332451
ClusterTAD: an unsupervised machine learning approach to detecting topologically associated domains of chromosomes from Hi-C data.

BACKGROUND: With the development of chromosomal conformation capturing techniques, particularly, the...

Nov 2017 29137603
Clinical and diagnostic features of Bartter and Gitelman syndromes.

BACKGROUND: Bartter and Gitelman syndromes are autosomal recessive disorders of renal tubular salt h...

Nov 2017 29942493
Radiomics and radiogenomics in lung cancer: A review for the clinician.

Lung cancer is responsible for a large proportion of cancer-related deaths across the globe, with de...

Nov 2017 29290259
Gene Prediction in Metagenomic Fragments with Deep Learning.

Next generation sequencing technologies used in metagenomics yield numerous sequencing fragments whi...

Nov 2017 29250541
Disease Gene Prediction by Integrating PPI Networks, Clinical RNA-Seq Data and OMIM Data.

Disease gene prediction is a challenging task that has a variety of applications such as early diagn...

Nov 2017 29990218
Machine learning model for sequence-driven DNA G-quadruplex formation.

We describe a sequence-based computational model to predict DNA G-quadruplex (G4) formation. The mod...

Nov 2017 29109402
An Ultralightweight and Living Legged Robot.

In this study, we describe the most ultralightweight living legged robot to date that makes it a str...

Nov 2017 29412086
Ruminal fermentation and microbial community differently influenced by four typical subtropical forages .

The present study evaluated the effects of 4 typical subtropical forages on ruminal microbial commun...

Nov 2017 30167491
Specific and intrinsic sequence patterns extracted by deep learning from intra-protein binding and non-binding peptide fragments.

The key finding in the DNA double helix model is the specific pairing or binding between nucleotides...

Nov 2017 29097708
De novo prediction of human chromosome structures: Epigenetic marking patterns encode genome architecture.

Inside the cell nucleus, genomes fold into organized structures that are characteristic of cell type...

Oct 2017 29087948
MRI features predict p53 status in lower-grade gliomas via a machine-learning approach.

BACKGROUND: P53 mutation status is a pivotal biomarker for gliomas. Here, we developed a machine-lea...

Oct 2017 29527478
McEnhancer: predicting gene expression via semi-supervised assignment of enhancers to target genes.

Transcriptional enhancers regulate spatio-temporal gene expression. While genomic assays can identif...

Oct 2017 29070071
Bacteria-inspired nanorobots with flagellar polymorphic transformations and bundling.

Wirelessly controlled nanoscale robots have the potential to be used for both in vitro and in vivo b...

Oct 2017 29074862
Open source machine-learning algorithms for the prediction of optimal cancer drug therapies.

Precision medicine is a rapidly growing area of modern medical science and open source machine-learn...

Oct 2017 29073279
Identification of immune signatures predictive of clinical protection from malaria.

Antibodies are thought to play an essential role in naturally acquired immunity to malaria. Prospect...

Oct 2017 29065113
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