Genetics

Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

11,155 articles

Subcategories: Genetics

Showing 6133-6153 of 11,155 articles

Model-Based Multifactor Dimensionality Reduction for Rare Variant Association Analysis.

Genome-wide association studies have revealed a vast amount of common loci associated to human compl...

Jul 2015 26201701

Multivariate Quantitative Multifactor Dimensionality Reduction for Detecting Gene-Gene Interactions.

OBJECTIVES: To determine gene-gene interactions and missing heritability of complex diseases is a ch...

Jul 2015 26201702

A mutation profile for top-k patient search exploiting Gene-Ontology and orthogonal non-negative matrix factorization.

MOTIVATION: As the quantity of genomic mutation data increases, the likelihood of finding patients w...

Jul 2015 26209432

KnowEnG: a knowledge engine for genomics.

We describe here the vision, motivations, and research plans of the National Institutes of Health Ce...

Jul 2015 26205246

Discrimination of driver and passenger mutations in epidermal growth factor receptor in cancer.

Cancer is one of the most life-threatening diseases and mutations in several genes are the vital cau...

Jul 2015 26264175

IMG-ABC: A Knowledge Base To Fuel Discovery of Biosynthetic Gene Clusters and Novel Secondary Metabolites.

UNLABELLED: In the discovery of secondary metabolites, analysis of sequence data is a promising expl...

Jul 2015 26173699

Binding Activity Prediction of Cyclin-Dependent Inhibitors.

The Cyclin-Dependent Kinases (CDKs) are the core components coordinating eukaryotic cell division cy...

Jul 2015 26079845

Machine learning approach for pooled DNA sample calibration.

BACKGROUND: Despite ongoing reduction in genotyping costs, genomic studies involving large numbers o...

Jul 2015 26156142

Genome Modeling System: A Knowledge Management Platform for Genomics.

In this work, we present the Genome Modeling System (GMS), an analysis information management system...

Jul 2015 26158448

Genomics and Machine Learning for Taxonomy Consensus: The Mycobacterium tuberculosis Complex Paradigm.

Infra-species taxonomy is a prerequisite to compare features such as virulence in different pathogen...

Jul 2015 26154264

CYP19A1 Genetic Polymorphisms rs4646 and Osteoporosis in Patients Treated with Aromatase Inhibitor-Based Adjuvant Therapy.

OBJECTIVE: Third-generation aromatase inhibitors (AI) are potent suppressors of aromatase activity. ...

Jul 2015 27026757

Application of comparative biology in GO functional annotation: the mouse model.

The Gene Ontology (GO) is an important component of modern biological knowledge representation with ...

Jul 2015 26141960

Prediction of hydrogen and carbon chemical shifts from RNA using database mining and support vector regression.

The Biological Magnetic Resonance Data Bank (BMRB) contains NMR chemical shift depositions for over ...

Jul 2015 26141454

A k-mer-based barcode DNA classification methodology based on spectral representation and a neural gas network.

OBJECTIVES: In this paper, an alignment-free method for DNA barcode classification that is based on ...

Jul 2015 26170017

Computational assignment of cell-cycle stage from single-cell transcriptome data.

The transcriptome of single cells can reveal important information about cellular states and heterog...

Jul 2015 26142758

An efficiency analysis of high-order combinations of gene-gene interactions using multifactor-dimensionality reduction.

BACKGROUND: Multifactor dimensionality reduction (MDR) is widely used to analyze interactions of gen...

Jul 2015 26126977

Artificial neural networks reveal efficiency in genetic value prediction.

The objective of this study was to evaluate the efficiency of artificial neural networks (ANNs) for ...

Jun 2015 26125887

Combined application of mixture experimental design and artificial neural networks in the solid dispersion development.

This study for the first time demonstrates combined application of mixture experimental design and a...

Jun 2015 26065534

Using Gene Ontology to describe the role of the neurexin-neuroligin-SHANK complex in human, mouse and rat and its relevance to autism.

BACKGROUND: People with an autistic spectrum disorder (ASD) display a variety of characteristic beha...

Jun 2015 26047810

Impact of relationships between test and training animals and among training animals on reliability of genomic prediction.

One of the factors affecting the reliability of genomic prediction is the relationship among the ani...

May 2015 26010512

Identification of genomic features in the classification of loss- and gain-of-function mutation.

BACKGROUND: Alterations of a genome can lead to changes in protein functions. Through these genetic ...

May 2015 26043747

Browse Categories