Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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RNA polymerase III transcription-associated polyadenylation promotes the accumulation of noncoding retrotransposons during infection.

UNLABELLED: The accumulation of RNA Polymerase III (Pol III) transcribed short interspersed nuclear ...

May 2025 40463246
A multi-objective evolutionary algorithm for detecting protein complexes in PPI networks using gene ontology.

Detecting protein complexes is crucial in computational biology for understanding cellular mechanism...

May 2025 40374682
Integrating bioinformatics and machine learning to identify glomerular injury genes and predict drug targets in diabetic nephropathy.

Diabetes mellitus (DM) is a chronic metabolic disorder that poses significant challenges to public h...

May 2025 40374840
Advancing optical nanosensors with artificial intelligence: A powerful tool to identify disease-specific biomarkers in multi-omics profiling.

Multi-omics profiling integrates genomic, epigenomic, transcriptomic, and proteomic data, essential ...

May 2025 39919475
Community-based Multi-Agent Reinforcement Learning with Transfer and Active Exploration

We propose a new framework for multi-agent reinforcement learning (MARL), where the agents coopera...

PDE: Gene Effect Inspired Parameter Dynamic Evolution for Low-light Image Enhancement

Low-light image enhancement (LLIE) is a fundamental task in computational photography, aiming to i...

WSCIF: A Weakly-Supervised Color Intelligence Framework for Tactical Anomaly Detection in Surveillance Keyframes

The deployment of traditional deep learning models in high-risk security tasks in an unlabeled, da...

Disentangled Pseudo-bag Augmentation for Whole Slide Image Multiple Instance Learning.

As the predominant approach for pathological whole slide image (WSI) classification, multiple instan...

May 2025 40366836
Single-cell RNA sequencing reveals immunological link between house dust mite allergy and childhood asthma.

Allergic asthma in children is typically associated with house dust mites (HDM) as the key allergen....

May 2025 40368964
Spatial transcriptomics reveals human cortical layer and area specification.

The human cerebral cortex is composed of six layers and dozens of areas that are molecularly and str...

May 2025 40369074
VEFill: a model for accurate and generalizable deep mutational scanning score imputation across protein domains.

BACKGROUND: Deep Mutational Scanning (DMS) assays can systematically assess the effects of amino aci...

May 2025 40463051
Alzheimer's subtypes A supervised, unsupervised, multimodal, multilayered embedded recursive (SUMMER) AI study.

Since Alzheimer's disease (AD) is a heterogeneous disease, different subtypes may have distinct biol...

May 2025 40463120
Personalized surveillance in colorectal cancer: Integrating circulating tumor DNA and artificial intelligence into post-treatment follow-up.

Given the growing burden of colorectal cancer (CRC) as a global health challenge, it becomes imperat...

May 2025 40496357
scPrediXcan integrates deep learning methods and single-cell data into a cell-type-specific transcriptome-wide association study framework.

Transcriptome-wide association studies (TWASs) help identify disease-causing genes but often fail to...

May 2025 40373737
Development of an automated artificial intelligence-based tool for reticulin fibrosis assessment in bone marrow biopsies.

Bone marrow fibrosis plays a critical role in the diagnosis, prognosis, and management of haematolog...

May 2025 40358741
Targeting high-risk multiple myeloma genotypes with optimized anti-CD70 CAR-T cells.

Despite the success of BCMA-targeting CAR-Ts in multiple myeloma, patients with high-risk cytogeneti...

May 2025 40359480
Predicting gene expression from DNA sequence using deep learning models.

Transcription of genes is regulated by DNA elements such as promoters and enhancers, the activity of...

May 2025 40360798
Sex differences in bladder cancer: understanding biological and clinical implications.

Bladder cancer (BC) remains a significant global health concern, with substantial sex and racial dis...

May 2025 40361239
Insights into KMT2A rearrangements in acute myeloid leukemia: from molecular characteristics to targeted therapies.

Acute myeloid leukemia (AML) with KMT2A rearrangements (KMT2A-r) represents a highly aggressive and ...

May 2025 40361241
Transcriptomic Profiling of Hypoxia-Adaptive Responses in Tibetan Goat Fibroblasts.

The Tibetan goat () exhibits remarkable adaptations to high-altitude hypoxia, yet the molecular mech...

May 2025 40427283
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