Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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Showing 694-714 of 11,038 articles
Endothelial cells recruit pro-inflammatory macrophage clusters via app-Cd74 exacerbating ICI-associated myocarditis.

Immune checkpoint inhibitor-related myocarditis (ICI-myocarditis) is a rare but highly threatening a...

Mar 2026 41905617
OMICS Data in the Diagnosis of Diabetic Retinopathy: A Comparison between Transcriptome Data and DNA Methylation Data.

PURPOSE: Diabetic retinopathy is a serious complication of diabetes that can damage the retina of th...

Mar 2026 41905706
Hypergraph Representations of Single-Cell RNA Sequencing Data for Improved Cell Clustering.

MOTIVATION: Single-cell RNA sequencing (scRNA-seq) data analysis is often performed using network pr...

Mar 2026 41896196
Advancing plant DNA barcoding: integrating chloroplast genome sequencing, cryptic diversity discovery and machine learning.

Accurate plant species identification underpins taxonomy, conservation, ecological monitoring, and t...

Mar 2026 41894059
IGH::FENDRR and specific KRAS mutations define a novel B-ALL molecular subtype with poor chemotherapy response.

Large scale sequencing efforts have defined up to 27 diagnostic entities in B-ALL, leaving few sampl...

Mar 2026 41894249
Beyond Percutaneous Coronary Intervention - Targeted Molecular Therapies for the Next Era of Coronary Care.

Coronary artery disease (CAD) remains the leading global cause of cardiovascular morbidity and morta...

Mar 2026 41903924
Leveraging weighted embedding and Transformer architecture to improve phenotype prediction of complex traits for crops.

Understanding the relationship between genomic variation and phenotype is fundamental to deciphering...

Mar 2026 41888146
What does it take to learn the rules of RNA base pairing? A lot less than you may think.

Amidst the fast-developing trend of RNA large language models with millions of parameters, we asked ...

Mar 2026 41888287
CRISPR/Cas12a: A Comprehensive Review from Structural Foundations to Applications in Nucleic Acid Precision Detection.

CRISPR/Cas12a technology, characterized by its distinctive trans-cleavage activity, has evolved beyo...

Mar 2026 41889087
Integrating single-cell and single-nucleus datasets improves bulk RNA-seq deconvolution.

Bulk RNA sequencing (RNA-seq) deconvolution typically uses single-cell RNA sequencing (scRNA-seq) re...

Mar 2026 41895263
CT Radiomic Features Are Associated with DNA Copy Number Alterations of Head and Neck Squamous Cell Carcinomas.

BACKGROUND AND PURPOSE: While a larger fraction of head and neck squamous cell carcinoma (HNSCC) gen...

Mar 2026 41067910
Deep learning-based precision phenotyping of spine curvature identifies novel genetic risk loci for scoliosis in the UK Biobank.

Scoliosis is the most common developmental spinal deformity, but its genetic underpinnings remain on...

Mar 2026 41882318
Molecularly Engineered SERS Platform with Microturbulence-Enhanced Electrohydrodynamics for Multiplexed Profiling of Lung Cancer ctDNA.

Precise profiling of multiple circulating tumor DNA (ctDNA) is hindered by the challenge of resolvin...

Mar 2026 41885059
DeepLMI: Deep Feature Mining with a Globally Enhanced Graph Convolutional Network for Robust lncRNA-miRNA Interaction Prediction.

MOTIVATION: Interactions between long non-coding RNAs (lncRNAs) and microRNAs (miRNAs) play pivotal ...

Mar 2026 41886347
Deconvolving cell-type-specific gene expression profiles from bulk RNA-seq samples.

Bulk RNA sequencing (bulk RNA-seq) and single-cell RNA sequencing (scRNA-seq) are two important high...

Mar 2026 41886524
Distinctive DNA sequence features define epigenetic longevity of inflammatory memory.

Tissues harbor memories of inflammation, which heighten sensitivity to diverse future assaults. Whet...

Mar 2026 41886579
A Deep Learning-Driven Framework Integrating Organoid-Based Functional Validation Identifies Universal Neoantigens from Recurrent Glioma Mutations.

Glioblastoma (GBM) is the most common malignant intracranial tumor in adults, with a median survival...

Mar 2026 41886621
Incorporating valuable prior knowledge to improve deep learning prediction of genetic perturbation responses.

Genetic perturbation response prediction plays a critical role in virtual cell research, yet the per...

Mar 2026 41887798
Computational Discovery of MERS-CoV Main Protease Inhibitors Through Screening and Molecular Dynamics Simulations.

Targeting the main protease (Mpro) of coronaviruses has emerged as a promising therapeutic strategy ...

Mar 2026 41887806
Machine learning-directed massively parallel programmable nucleic acid amplification.

Dynamic regulation of amplification efficiency is pivotal yet challenging in molecular diagnostics a...

Mar 2026 41880514
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