Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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Deep learning reveals determinants of transcriptional infidelity at nucleotide resolution in the allopolyploid line by goldfish and common carp hybrids.

During DNA transcription, the central dogma states that DNA generates corresponding RNA sequences ba...

May 2025 40471993
PackPPI: An integrated framework for protein-protein complex side-chain packing and ΔΔG prediction based on diffusion model.

Deep learning methods have played an increasingly pivotal role in advancing side-chain packing and m...

May 2025 40260988
DeepRNA-Twist: language-model-guided RNA torsion angle prediction with attention-inception network.

RNA torsion and pseudo-torsion angles are critical in determining the three-dimensional conformation...

May 2025 40315431
Optimizing Treatment: The Role of Pharmacology, Genomics, and AI in Improving Patient Outcomes.

Recent advances in pharmacology are revolutionizing drug discovery and treatment strategies through ...

May 2025 40285487
GPA-RAM: Grasp-Pretraining Augmented Robotic Attention Mamba for Spatial Task Learning

Most existing robot manipulation methods prioritize task learning by enhancing perception through ...

On learning functions over biological sequence space: relating Gaussian process priors, regularization, and gauge fixing

Mappings from biological sequences (DNA, RNA, protein) to quantitative measures of sequence functi...

Representation Learning for Distributional Perturbation Extrapolation

We consider the problem of modelling the effects of unseen perturbations such as gene knockdowns o...

3plex Web: An Interactive Platform for RNA:DNA Triplex Prediction and Analysis

Summary: Long non-coding RNAs (lncRNAs) exert their functions by cooperating with other molecules ...

A Comprehensive Review on RNA Subcellular Localization Prediction

The subcellular localization of RNAs, including long non-coding RNAs (lncRNAs), messenger RNAs (mR...

DTC-m6Am: A Framework for Recognizing N6,2'-O-dimethyladenosine Sites in Unbalanced Classification Patterns Based on DenseNet and Attention Mechanisms.

BACKGROUND: mAm is a specific RNA modification that plays an important role in regulating mRNA stabi...

Apr 2025 40302345
Bidirectional Mamba for Single-Cell Data: Efficient Context Learning with Biological Fidelity

Single-cell RNA sequencing (scRNA-seq) enables high-resolution analysis of cellular heterogeneity,...

Real-time raw signal genomic analysis using fully integrated memristor hardware

Advances in third-generation sequencing have enabled portable and real-time genomic sequencing, bu...

Molecular Determinants of Orthosteric-allosteric Dual Inhibition of PfHT1 by Computational Assessment

To overcome antimalarial drug resistance, carbohydrate derivatives as selective PfHT1 inhibitor ha...

Multi-modal single-cell foundation models via dynamic token adaptation

Recent advances in applying deep learning in genomics include DNA-language and single-cell foundat...

TransST: Transfer Learning Embedded Spatial Factor Modeling of Spatial Transcriptomics Data

Background: Spatial transcriptomics have emerged as a powerful tool in biomedical research because...

Can LLMs Assist Expert Elicitation for Probabilistic Causal Modeling?

Objective: This study investigates the potential of Large Language Models (LLMs) as an alternative...

VibrantLeaves: A principled parametric image generator for training deep restoration models

Even though Deep Neural Networks are extremely powerful for image restoration tasks, they have sev...

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