Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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Hallucination Detection in Large Language Models with Metamorphic Relations

Large Language Models (LLMs) are prone to hallucinations, e.g., factually incorrect information, i...

Towards Accurate Binary Spiking Neural Networks: Learning with Adaptive Gradient Modulation Mechanism

Binary Spiking Neural Networks (BSNNs) inherit the eventdriven paradigm of SNNs, while also adopti...

Optimizing Gene-Based Testing for Antibiotic Resistance Prediction

Antibiotic Resistance (AR) is a critical global health challenge that necessitates the development...

Learning to Discover Regulatory Elements for Gene Expression Prediction

We consider the problem of predicting gene expressions from DNA sequences. A key challenge of this...

BOLIMES: Boruta and LIME optiMized fEature Selection for Gene Expression Classification

Gene expression classification is a pivotal yet challenging task in bioinformatics, primarily due ...

A linear-time algorithm computing the resident fitness in interacting trajectories

The notion of a system of interacting trajectories was recently introduced by Hermann, Gonz\'alez ...

Be Cautious When Merging Unfamiliar LLMs: A Phishing Model Capable of Stealing Privacy

Model merging is a widespread technology in large language models (LLMs) that integrates multiple ...

Do we Really Need Visual Instructions? Towards Visual Instruction-Free Fine-tuning for Large Vision-Language Models

Visual instruction tuning has become the predominant technology in eliciting the multimodal task-s...

HybriDNA: A Hybrid Transformer-Mamba2 Long-Range DNA Language Model

Advances in natural language processing and large language models have sparked growing interest in...

ControllableGPT: A Ground-Up Designed Controllable GPT for Molecule Optimization

Large Language Models (LLMs) employ three popular training approaches: Masked Language Models (MLM...

Complex Network Modelling with Power-law Activating Patterns and Its Evolutionary Dynamics

Complex network theory provides a unifying framework for the study of structured dynamic systems. ...

Genetic Data Governance in Crisis: Policy Recommendations for Safeguarding Privacy and Preventing Discrimination

Genetic data collection has become ubiquitous today. The ability to meaningfully interpret genetic...

Leveraging Machine Learning and Deep Learning Techniques for Improved Pathological Staging of Prostate Cancer

Prostate cancer (Pca) continues to be a leading cause of cancer-related mortality in men, and the ...

scMamba: A Pre-Trained Model for Single-Nucleus RNA Sequencing Analysis in Neurodegenerative Disorders

Single-nucleus RNA sequencing (snRNA-seq) has significantly advanced our understanding of the dise...

Advancing Precision Oncology Through Modeling of Longitudinal and Multimodal Data

Cancer evolves continuously over time through a complex interplay of genetic, epigenetic, microenv...

CausalGeD: Blending Causality and Diffusion for Spatial Gene Expression Generation

The integration of single-cell RNA sequencing (scRNA-seq) and spatial transcriptomics (ST) data is...

Whole-Genome Phenotype Prediction with Machine Learning: Open Problems in Bacterial Genomics

How can we identify causal genetic mechanisms that govern bacterial traits? Initial efforts entrus...

Life-Code: Central Dogma Modeling with Multi-Omics Sequence Unification

The interactions between DNA, RNA, and proteins are fundamental to biological processes, as illust...

GENERator: A Long-Context Generative Genomic Foundation Model

Advancements in DNA sequencing technologies have significantly improved our ability to decode geno...

A Simple yet Effective DDG Predictor is An Unsupervised Antibody Optimizer and Explainer

The proteins that exist today have been optimized over billions of years of natural evolution, dur...

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