Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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AggNet: Advancing protein aggregation analysis through deep learning and protein language model.

Protein aggregation is critical to various biological and pathological processes. Besides, it is als...

Feb 2025 39840791
Constructing a Prognostic Model for Subtypes of Colorectal Cancer Based on Machine Learning and Immune Infiltration-Related Genes.

This study constructed a prognostic model combining machine learning-based immune infiltration-relat...

Feb 2025 40008534
No Foundations without Foundations -- Why semi-mechanistic models are essential for regulatory biology

Despite substantial efforts, deep learning has not yet delivered a transformative impact on elucid...

A network-driven framework for enhancing gene-disease association studies in coronary artery disease

Over the last decade, genome-wide association studies (GWAS) have successfully identified numerous...

Context Matters: Query-aware Dynamic Long Sequence Modeling of Gigapixel Images

Whole slide image (WSI) analysis presents significant computational challenges due to the massive ...

Blocked Bloom Filters with Choices

Probabilistic filters are approximate set membership data structures that represent a set of keys ...

Identification of DNA damage repair-related genes in sepsis using bioinformatics and machine learning: An observational study.

Sepsis is a life-threatening disease with a high mortality rate, for which the pathogenetic mechanis...

Jan 2025 39889168
Glioma Multimodal MRI Analysis System for Tumor Layered Diagnosis via Multi-task Semi-supervised Learning

Gliomas are the most common primary tumors of the central nervous system. Multimodal MRI is widely...

Algorithmic Segmentation and Behavioral Profiling for Ransomware Detection Using Temporal-Correlation Graphs

The rapid evolution of cyber threats has outpaced traditional detection methodologies, necessitati...

Molecular-driven Foundation Model for Oncologic Pathology

Foundation models are reshaping computational pathology by enabling transfer learning, where model...

Multivariate Feature Selection and Autoencoder Embeddings of Ovarian Cancer Clinical and Genetic Data

This study explores a data-driven approach to discovering novel clinical and genetic markers in ov...

Intelligent Code Embedding Framework for High-Precision Ransomware Detection via Multimodal Execution Path Analysis

Modern threat landscapes continue to evolve with increasing sophistication, challenging traditiona...

Diffusion Generative Modeling for Spatially Resolved Gene Expression Inference from Histology Images

Spatial Transcriptomics (ST) allows a high-resolution measurement of RNA sequence abundance by sys...

GiantHunter: Accurate detection of giant virus in metagenomic data using reinforcement-learning and Monte Carlo tree search

Motivation: Nucleocytoplasmic large DNA viruses (NCLDVs) are notable for their large genomes and e...

From In Silico to In Vitro: A Comprehensive Guide to Validating Bioinformatics Findings

The integration of bioinformatics predictions and experimental validation plays a pivotal role in ...

Efficient Sparse Flow Decomposition Methods for RNA Multi-Assembly

Decomposing a flow on a Directed Acyclic Graph (DAG) into a weighted sum of a small number of path...

Detection and Classification of Acute Lymphoblastic Leukemia Utilizing Deep Transfer Learning

A mutation in the DNA of a single cell that compromises its function initiates leukemia,leading to...

Machine learning-optimized targeted detection of alternative splicing.

RNA sequencing (RNA-seq) is widely adopted for transcriptome analysis but has inherent biases that h...

Jan 2025 39727154
Human Genome Book: Words, Sentences and Paragraphs

Since the completion of the human genome sequencing project in 2001, significant progress has been...

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