Latest AI and machine learning research in genetics for healthcare professionals.
The regulatory genome encodes the logic that governs gene expression, enabling cells to respond to d...
MicroRNA (miRNA) abundance reflects a dynamic balance between biogenesis, target engagement and deca...
DNA-encoded libraries (DELs) are powerful tools for initial hit identification, yet the combinatoria...
Age-based population models are a gold standard approach to estimate stock size and sustainable catc...
Disease-associated genetic variants occur extensively in noncoding regions like promoters, but curre...
Alternative splicing (AS) of pre-mRNA plays a crucial role in tissue-specific gene regulation, with ...
The process by which a foreign gene is introduced into a cell and translated into a functional prote...
Quantifying tissue molecular and physical integrity is essential for biobank development. However, c...
Formalin-fixed paraffin-embedded (FFPE) tissues are widely used in clinical and research settings, y...
Despite their potential, current precision oncology approaches benefit only a small fraction of pati...
Enhancers play an important role in transcriptional regulation by modulating gene expression from di...
The ability of organisms to adapt and survive depends on the effects of genes and the environment on...
In targeted spatial transcriptomics technologies, a key challenge is to select an informative gene p...
Facioscapulohumeral muscular dystrophy (FSHD) is an autosomal dominant muscle disorder characterized...
Precise modeling of RNA-ligand interactions is essential for understanding RNA functionality and des...
Predicting disease risk from DNA presents an unprecedented emerging challenge as biobanks approach p...
Alzheimer’s disease (AD) is a major global health concern, expected to affect 12.7 million Americans...
Predicting whether single amino acid variants (SAVs) in proteins lead to pathogenic outcomes is a cr...
Analogous to the Encyclopedia of DNA Elements (ENCODE) project, the Functional Annotation of ANimal ...
Epigenetic clocks are widely used to estimate biological aging, yet most are built from array-based ...
Neural circuits emerge during development through dynamic interactions between genetic instructions ...