Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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Showing 8569-8589 of 11,255 articles
Deep-Learning Uncovers certain CCM Isoforms as Transcription Factors.

BACKGROUND: Cerebral Cavernous Malformations (CCMs) are brain vascular abnormalities associated with...

Feb 2024 38420834
Deep Learning of Multimodal Ultrasound: Stratifying the Response to Neoadjuvant Chemotherapy in Breast Cancer Before Treatment.

BACKGROUND: Not only should resistance to neoadjuvant chemotherapy (NAC) be considered in patients w...

Feb 2024 37669223
Global trends and hotspots of ulcerative colitis based on bibliometric and visual analysis from 1993 to 2022.

Ulcerative colitis (UC) has seen a significant increase over the past 3 decades. However, our unders...

Feb 2024 38306541
DeepLocRNA: an interpretable deep learning model for predicting RNA subcellular localization with domain-specific transfer-learning.

MOTIVATION: Accurate prediction of RNA subcellular localization plays an important role in understan...

Feb 2024 38317052
scSemiGCN: boosting cell-type annotation from noise-resistant graph neural networks with extremely limited supervision.

MOTIVATION: Cell-type annotation is fundamental in revealing cell heterogeneity for single-cell data...

Feb 2024 38366925
scMMT: a multi-use deep learning approach for cell annotation, protein prediction and embedding in single-cell RNA-seq data.

Accurate cell type annotation in single-cell RNA-sequencing data is essential for advancing biologic...

Jan 2024 38300515
Deqformer: high-definition and scalable deep learning probe design method.

Target enrichment sequencing techniques are gaining widespread use in the field of genomics, prized ...

Jan 2024 38305453
Self-supervised deep learning of gene-gene interactions for improved gene expression recovery.

Single-cell RNA sequencing (scRNA-seq) has emerged as a powerful tool to gain biological insights at...

Jan 2024 38349062
CRISPR-DIPOFF: an interpretable deep learning approach for CRISPR Cas-9 off-target prediction.

CRISPR Cas-9 is a groundbreaking genome-editing tool that harnesses bacterial defense systems to alt...

Jan 2024 38388680
Enhancer-MDLF: a novel deep learning framework for identifying cell-specific enhancers.

Enhancers, noncoding DNA fragments, play a pivotal role in gene regulation, facilitating gene transc...

Jan 2024 38485768
Characterizing and predicting ccRCC-causing missense mutations in Von Hippel-Lindau disease.

BACKGROUND: Mutations within the Von Hippel-Lindau (VHL) tumor suppressor gene are known to cause VH...

Jan 2024 37883464
Enabling the clinical application of artificial intelligence in genomics: a perspective of the AMIA Genomics and Translational Bioinformatics Workgroup.

OBJECTIVE: Given the importance AI in genomics and its potential impact on human health, the America...

Jan 2024 38037121
Application of Genomic Data in Translational Medicine During the Big Data Era.

Advances in gene sequencing technology and decreasing costs have resulted in a proliferation of geno...

Jan 2024 38287799
Multiple sequence alignment-based RNA language model and its application to structural inference.

Compared with proteins, DNA and RNA are more difficult languages to interpret because four-letter co...

Jan 2024 37941140
Deep learning predicts therapy-relevant genetics in acute myeloid leukemia from Pappenheim-stained bone marrow smears.

The detection of genetic aberrations is crucial for early therapy decisions in acute myeloid leukemi...

Jan 2024 37967385
BioKA: a curated and integrated biomarker knowledgebase for animals.

Biomarkers play an important role in various area such as personalized medicine, drug development, c...

Jan 2024 37843156
SLKB: synthetic lethality knowledge base.

Emerging CRISPR-Cas9 technology permits synthetic lethality (SL) screening of large number of gene p...

Jan 2024 37889037
The Reactome Pathway Knowledgebase 2024.

The Reactome Knowledgebase (https://reactome.org), an Elixir and GCBR core biological data resource,...

Jan 2024 37941124
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