Latest AI and machine learning research in genetics for healthcare professionals.
PURPOSE: Quantifying the risk of cancer associated with pathogenic mutations in germline cancer susc...
With the avalanche of biological sequences generated in the post-genomic age, one of the most challe...
Currently, the development of medicines for complex diseases requires the development of combination...
MOTIVATION: The genetic architecture of diseases becomes increasingly known. This raises difficultie...
MOTIVATION: Deep learning architectures have recently demonstrated their power in predicting DNA- an...
MOTIVATION: Human genomic datasets often contain sensitive information that limits use and sharing o...
SUMMARY: Support Vector Machines with gapped k-mer kernels (gkm-SVMs) have been used to learn predic...
MOTIVATION: Messenger RNA subcellular localization mechanisms play a crucial role in post-transcript...
MOTIVATION: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease caused by aberrations...
Promoter region of protein-coding genes are gradually being well understood, yet no comparable studi...
RNA modification plays an indispensable role in the regulation of organisms. RNA modification site p...
Protein-protein Interactions are involved in most fundamental biological processes, with disease cau...
MOTIVATION: Gene expression prediction is one of the grand challenges in computational biology. The ...
As a data-driven science, genomics largely utilizes machine learning to capture dependencies in data...
The prognosis management is crucial for highrisk disease like Acute Myeloid Leukemia (AML) in order ...
Interactions between regulatory elements are of crucial importance for the understanding of transcri...
MOTIVATION: With the accumulation of DNA sequencing data, convolution neural network (CNN) based met...
BACKGROUND: Phages and plasmids are the major components of mobile genetic elements, and fragments f...
MOTIVATION: One of the main challenges in machine learning (ML) is choosing an appropriate normaliza...
MOTIVATION: The de novo prediction of RNA tertiary structure remains a grand challenge. Predicted RN...
Chip-based digital assays such as the digital polymerase chain reaction (digital PCR), digital loop-...