Latest AI and machine learning research in genetics for healthcare professionals.
Leveraging the powerful generation capability of large-scale pretrained text-to-image models, training-free methods have demonstrated impressive image editing results. Conventional diffusion-based methods, as well as recent rectified flow (RF)-based methods, typically reverse synthesis trajectories by gradually adding noise to clean images, during which the noisy latent at the current timestep i...
Genomic selection (GS) emerged as a key part of the solution to ensure the food supply for the growing human population thanks to advances in genotyping and other enabling technologies and improved understanding of the genotype-phenotype relationship in quantitative genetics. GS is a breeding strategy to predict the genotypic values of individuals for selection using their genotypic data and a tra...
Achieving significant genetic gains in grain yield (GY) in wheat (Triticum aestivum L.) requires optimization of the key biomass partitioning traits s...
Pharmacogenetics is a promising strategy to facilitate individualized care for patients with Major Depressive Disorder (MDD). Research is ongoing to i...
publishes research, technical developments, and reviews related to cardiac, vascular, and thoracic imaging. The current review article, led by the t...
Osteoarthritis is a multifactorial condition marked by the gradual deterioration of joint cartilage, synovial inflammation, alterations in the subchon...
For important food crops such as the common bean (Phaseolus vulgaris, L.), global demand continues to outpace the rate of genetic gain for quantitativ...
Colorectal cancer (CRC) remains a major cause of cancer-related deaths worldwide, with early detection being crucial for improving survival rates. Des...
Organoids, 3D cellular models derived from stem cells, have revolutionized drug testing by providing human-relevant systems for modeling diseases and ...
Adeno-associated virus (AAV) is a non-enveloped DNA virus infecting a wide variety of species, tissues, and cell types, which is recognized as a safe ...
Predicting the functional impact of single-point mutations on protein residual activity, especially after high-temperature incubation, is critical in ...
UNLABELLED: Fibrolamellar carcinoma (FLC) is a rare form of liver carcinoma with limited diagnostic and therapeutic options. In this study, we utilize...
The clinical benefits of neoadjuvant chemoimmunotherapy (NACI) are demonstrated in patients with bladder cancer (BCa); however, more than half fail to...
Cysteine cathepsins have been discovered to be substantially expressed in multiple types of cancer. They play a key role in the progression and growth...
OBJECTIVES: The resting-state cerebral functional activity underlying chronic insomnia disorder (CID) remains inconsistent, and the effects of pharmac...
The renal thick ascending limb (TAL) plays a key role in water and ion homeostasis. Apical potassium secretion via the renal outer medullary potassium...
Cyclin-dependent kinase 4/6 inhibitors (CDK4/6i) have reshaped the treatment paradigm of hormone receptor positive (HRÂ +Â )/HER2-negative breast cancer...
BACKGROUND: Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder with increasing prevalence. While genetics play a strong causal role, amon...
Wastewater sampling has been shown to be an effective tool for monitoring the dynamics of an infectious disease. During the COVID-19 pandemic, many sa...
DNA methylation is a critical epigenetic modification that plays a central role in gene regulation, cellular differentiation, and the development of v...