Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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microRPM: a microRNA prediction model based only on plant small RNA sequencing data.

MOTIVATION: MicroRNAs (miRNAs) are endogenous non-coding small RNAs (of about 22 nucleotides), which...

Apr 2018 29136092
[Artificial Intelligence in Drug Discovery].

According to the increase of data generated from analytical instruments, application of artificial i...

Apr 2018 29650810
High Activity Target-Site Identification Using Phenotypic Independent CRISPR-Cas9 Core Functionality.

The activity of CRISPR-Cas9 target sites can be measured experimentally through phenotypic assays or...

Apr 2018 31021206
Research progress in machine learning methods for gene-gene interaction detection.

Complex diseases are results of gene-gene and gene-environment interactions. However, the detection ...

Mar 2018 29576545
Chromatin accessibility prediction via a hybrid deep convolutional neural network.

MOTIVATION: A majority of known genetic variants associated with human-inherited diseases lie in non...

Mar 2018 29069282
ICG: a wiki-driven knowledgebase of internal control genes for RT-qPCR normalization.

Real-time quantitative PCR (RT-qPCR) has become a widely used method for accurate expression profili...

Jan 2018 29036693
The Reactome Pathway Knowledgebase.

The Reactome Knowledgebase (https://reactome.org) provides molecular details of signal transduction,...

Jan 2018 29145629
Gramene 2018: unifying comparative genomics and pathway resources for plant research.

Gramene (http://www.gramene.org) is a knowledgebase for comparative functional analysis in major cro...

Jan 2018 29165610
BioMuta and BioXpress: mutation and expression knowledgebases for cancer biomarker discovery.

Single-nucleotide variation and gene expression of disease samples represent important resources for...

Jan 2018 30053270
Annotating gene sets by mining large literature collections with protein networks.

Analysis of patient genomes and transcriptomes routinely recognizes new gene sets associated with hu...

Jan 2018 29218918
Applications of Support Vector Machine (SVM) Learning in Cancer Genomics.

Machine learning with maximization (support) of separating margin (vector), called support vector ma...

Jan 2018 29275361
Survey of Computational Approaches for Prediction of DNA-Binding Residues on Protein Surfaces.

The increasing number of protein structures with uncharacterized function necessitates the developme...

Jan 2018 29536446
[Construction of a High-precision Chemical Prediction System Using Human ESCs].

 Toxicity prediction based on stem cells and tissue derived from stem cells plays a very important r...

Jan 2018 29863053
MetaVW: Large-Scale Machine Learning for Metagenomics Sequence Classification.

Metagenomics is the study of microbial community diversity, especially the uncultured microorganisms...

Jan 2018 30030800
Deep Forest-based Prediction of Protein Subcellular Localization.

MOTIVATION: Knowledge of the correct protein subcellular localization is necessary for understanding...

Jan 2018 30209998
Spatial Analysis of Functional Enrichment (SAFE) in Large Biological Networks.

Spatial analysis of functional enrichment (SAFE) is a systematic quantitative approach for annotatin...

Jan 2018 30421408
Machine Learning Methods in Precision Medicine Targeting Epigenetic Diseases.

BACKGROUND: On a tide of big data, machine learning is coming to its day. Referring to huge amounts ...

Jan 2018 30421670
Immunomodulation of Zerumbone via Decreasing the Production of Reactive Oxygen Species from Immune Cells.

BACKGROUND AND OBJECTIVE: Zerumbone has been reported to exert anti-inflammatory, anti-ulcer and ant...

Jan 2018 30724050
Potential Anticancer Activity of the Parasol Mushroom, Macrolepiota procera (Agaricomycetes), against the A549 Human Lung Cancer Cell Line.

Mushrooms comprise an unlimited source of active compounds that have beneficial health effects witho...

Jan 2018 30806231
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