Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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Community-Wide Evaluation of Computational Function Prediction.

A biological experiment is the most reliable way of assigning function to a protein. However, in the...

Jan 2017 27812940
Annotation Extensions.

The specificity of knowledge that Gene Ontology (GO) annotations currently can represent is still re...

Jan 2017 27812947
A Gene Selection Method for Microarray Data Based on Binary PSO Encoding Gene-to-Class Sensitivity Information.

Traditional gene selection methods for microarray data mainly considered the features' relevance by ...

Jan 2017 28182545
Identifying Biomarkers of Hepatocellular Carcinoma Based on Gene Co-Expression Network from High-Throughput Data.

In this paper, we proposed an approach systematically based on the use of gene co-expression network...

Jan 2017 29295180
A neural network prediction of environmental determinants of Anopheles sinensis knockdown resistance mutation to pyrethroids in China.

Selection pressure caused by long-term intensive use of insecticides is the key driving force in res...

Dec 2016 27860007
The Effects of First-Line Anti-Tuberculosis Drugs on the Actions of Vitamin D in Human Macrophages.

Tuberculosis (TB) is a major global health problem. Patients with TB have a high rate of vitamin D d...

Dec 2016 28111615
Cell Free DNA and Procalcitonin as Early Markers of Complications in ICU Patients with Multiple Trauma and Major Surgery.

BACKGROUND: Cell free DNA (cfDNA) was recently suggested as a new marker of sepsis and poor outcome ...

Dec 2016 28164563
Aneuploidy of chromosome 8 in circulating tumor cells correlates with prognosis in patients with advanced gastric cancer.

OBJECTIVE: Previous work indicated that aneuploidy of chromosome 8 in circulating tumor cells (CTCs)...

Dec 2016 28174486
Identifying RNA 5-methylcytosine sites via pseudo nucleotide compositions.

RNA 5-methylcytosine (mC) plays an important role in numerous biological processes. Accurate identif...

Oct 2016 27531244
The effectiveness of argumentation in tutorial dialogues with an Intelligent Tutoring System for genetic risk of breast cancer.

BRCA Gist is an Intelligent Tutoring System that helps women understand issues related to genetic te...

Sep 2016 26511370
Higher order methylation features for clustering and prediction in epigenomic studies.

MOTIVATION: DNA methylation is an intensely studied epigenetic mark, yet its functional role is inco...

Sep 2016 27587656
Complementary feature selection from alternative splicing events and gene expression for phenotype prediction.

MOTIVATION: A central task of bioinformatics is to develop sensitive and specific means of providing...

Sep 2016 27587658
A unified model based multifactor dimensionality reduction framework for detecting gene-gene interactions.

MOTIVATION: Gene-gene interaction (GGI) is one of the most popular approaches for finding and explai...

Sep 2016 27587680
DeepChrome: deep-learning for predicting gene expression from histone modifications.

MOTIVATION: Histone modifications are among the most important factors that control gene regulation....

Sep 2016 27587684
Association of ATP-Binding Cassette Transporter (ABC) Gene Polymorphisms with Viral Load in Patients with Genotype 1 Hepatitis C Virus Infection.

BACKGROUND: ATP-binding cassette transporters (ABC) gene polymorphisms are associated with various b...

Sep 2016 28164591
Protective effect of Yiguanjian decoction against DNA damage on concanavalin A-induced liver injury mice model.

OBJECTIVE: To investigate the inhibitory effect of Yiguanjian decoction (YD) on DNA damage in Concan...

Aug 2016 28459511
Genotoxicity in lead treated human lymphocytes evaluated by micronucleus and comet assays.

Lead (Pb) which plays a significant role in modern industry is related to a broad range of physiolog...

Aug 2016 28577517
Convolutional neural network architectures for predicting DNA-protein binding.

MOTIVATION: Convolutional neural networks (CNN) have outperformed conventional methods in modeling t...

Jun 2016 27307608
What is information?

Molecular biology is based on two great discoveries: the first is that genes carry hereditary inform...

Mar 2016 26857676
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