Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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Showing 1072-1092 of 11,636 articles
Identification and validation of biomarkers associated with mitochondria and glycometabolism in gestational diabetes mellitus.

Gestational diabetes mellitus (GDM) can elevate the likelihood of developing high blood pressure dur...

Jun 2026 42374095
Explainable machine learning identifies small high-performance gene signatures from full transcriptomes in human liver preservation cohorts.

Transcriptomic studies of liver preservation and ischemia-reperfusion injury (IRI) often report larg...

Jun 2026 42374126
Integrated multi-omics analysis reveals folate metabolism-related genes as prognostic markers and therapeutic targets in clear cell renal cell carcinoma.

BACKGROUND: Clear cell renal cell carcinoma (ccRCC) is an aggressive tumor with high metastatic pote...

Jun 2026 42374231
An interpretable machine learning model integrating peripheral blood lncRNAs and clinical variables for phase classification in chronic myeloid leukemia.

BACKGROUND: Accurate disease phase assessment remains clinically important in chronic myeloid leukem...

Jun 2026 42374374
Decoding glioblastoma evolution and heterogeneity through mechanistic modeling: implications for clinical translation.

Glioblastoma (GBM) is one of the most aggressive and lethal primary brain tumors in adults, characte...

Jun 2026 42374477
Identification of distinct subgroups in Chinese patients with Behçet's syndrome via cluster analysis of immune cells and clinical features.

OBJECTIVES: This study aimed to use machine learning to explore Behçet's syndrome (BS) heterogeneity...

(1)
Jun 2026 42366396
Deep contrastive learning framework identifies cell-type-specific drug targets in Alzheimer's disease.

INTRODUCTION: Identifying disease-modifying drug targets is crucial for developing effective Alzheim...

(1)
Jun 2026 42382038
Role of Artificial Intelligence in bioinformatics: Revolutionizing molecular docking and DNA tokenization.

Bioinformatics has become a crucial discipline that connects biology and computational analysis, ext...

Jun 2026 42391906
Nanocarrier-Based Gene Delivery Systems: Mechanisms, Clinical Translation, and Future Perspectives.

Gene therapy holds revolutionary potential for managing genetic disorders, cancers and infectious il...

Jun 2026 42366709
Minimizing Off-Target Effects of CRISPR-Cas9 With Optimized sgRNA: Evaluation of Efficiency and Specificity in the Tumor Protein 53 (TP53) Region.

CRISPR-Cas9 is a widely used genetic tool with therapeutic potential in molecular biology. CRISPR-Ca...

Jun 2026 42366734
Benchmarking docking and ML re-scoring screening performance for KRAS G12D in pancreatic cancer.

The KRAS G12D mutation is commonly found in pancreatic cancer and is integral to the cell signaling ...

Jun 2026 42365569
Calcineurin-Dependent Stress Adaptation Enables Caspofungin Heteroresistance Leading to Stable Resistance in Candida Glabrata.

Antifungal heteroresistance has emerged as a clinical challenge across diverse species. In Candida g...

Jun 2026 42365577
Unveiling tumor heterogeneity by single cell RNA-sequencing: from basic considerations to clinical applications.

Tumor heterogeneity-encompassing diverse cellular phenotypes, genomic alterations, and micro-environ...

Jun 2026 42365863
Simulating the Dedifferentiation Process of Thyroid Cancer: Insights from Mouse Models and Ultrasound Imaging.

RATIONALE AND OBJECTIVE: Anaplastic thyroid carcinoma (ATC) may arise from the progression of differ...

(1)
Jun 2026 42366146
Identifying coagulation-related biomarkers in steroid-induced osteonecrosis of the femoral head: implications for early diagnosis and treatment.

Steroid-induced osteonecrosis of the femoral head (SONFH) is closely associated with coagulation dys...

(2)
Jun 2026 42366267
Machine learning approaches to identify genetic markers for goat climatic adaptation.

UNLABELLED: Whole-genome SNP data from 109 goats, including 55 indigenous Indian goats and 54 exotic...

Jun 2026 42371591
Pharmacogenomic characterization of a uric acid metabolism-related signature associated with prognosis and drug sensitivity in gastric cancer.

Gastric cancer (GC) remains a major cause of cancer-related mortality worldwide. Increasing evidence...

Jun 2026 42363944
Pan-cancer analysis identifies immunoproteasome as the predominant survival-associated component of antigen processing machinery.

Neoantigens are critical targets for cancer immunotherapy, yet the relationship between experimental...

Jun 2026 42364494
Multi-cohort integration and machine learning identify CPVL as a novel oncogenic driver in gastric cancer.

BACKGROUND: Gastric cancer (GC) remains a leading cause of cancer-related mortality worldwide, and t...

(1)
Jun 2026 42365218
Spatiotemporal genomic analysis and risk assessment of the plasmids carrying blaOXA-48-like genes based on a large-scale international dataset.

BACKGROUND: The spread of OXA-48-like carbapenemases represents a major public health challenge. Alt...

(1)
Jun 2026 42365253
A robust ATUB-Net for bearing fault diagnosis under unbalanced sample scenarios.

In order to achieve outstanding fault diagnosis classification performance, most deep learning-based...

(3)
Jun 2026 42379971
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