Latest AI and machine learning research in genetics for healthcare professionals.
OBJECTIVES: To evaluate the performance of machine learning models in predicting pathological complete response (pCR) to neoadjuvant chemoradiotherapy (nCRT) in patients with rectal cancer using magnetic resonance imaging.
Mobile genetic elements (MGEs) are as ubiquitous in nature as they are varied in type, ranging from viral insertions to transposons to incorporated plasmids. Horizontal transfer of MGEs across bacterial species may also pose a significant threat to global health due to their capability to harbour antibiotic resistance genes. However, despite cheap and rapid whole genome sequencing, the varied na...
Tandem mass spectrometry has played a pivotal role in advancing proteomics, enabling the high-throughput analysis of protein composition in biologic...
Behavior-disease models suggest that pandemics can be contained cost-effectively if individuals take preventive actions when disease prevalence rise...
De novo molecule generation allows the search for more drug-like hits across a vast chemical space. However, lead optimization is still required, an...
In silico methods evaluating the mutation effects of missense mutations are providing an important approach for understanding mutations in personal ...
Lung cancer, which accounts for about 18% of all cancer-related deaths worldwide, has a dismal 5-year survival rate of less than 20%. Survival rates f...
Recent advancements in single-cell genomics necessitate precision in gene panel selection to interpret complex biological data effectively. Those me...
Rh phenotype matching reduces but does not eliminate alloimmunization in patients with sickle cell disease (SCD) due to RH genetic diversity that is n...
Recent advances in multi-modal algorithms have driven and been driven by the increasing availability of large image-text datasets, leading to signif...
To identify diagnostic markers related to oxidative stress in chronic rhinosinusitis with nasal polyps (CRSwNP) by analyzing transcriptome sequencing...
The advent of online genomic data-sharing services has sought to enhance the accessibility of large genomic datasets by allowing queries about genet...
In this paper, we compare Bayesian Optimization, Differential Evolution, and an Evolution Strategy employed as a gait-learning algorithm in modular ro...
BACKGROUND: This study evaluated whether generative artificial intelligence (AI)-based augmentation (GAA) can provide diverse and realistic imaging ph...
UNLABELLED: Tumor type guides clinical treatment decisions in cancer, but histology-based diagnosis remains challenging. Genomic alterations are highl...
The Genomic Foundation Model (GFM) paradigm is expected to facilitate the extraction of generalizable representations from massive genomic data, the...
Spiking neural membrane systems (or spiking neural P systems, SNP systems) are a new type of computation model which have attracted the attention of p...
Prokaryotic DNA binding proteins (DBPs) play pivotal roles in governing gene regulation, DNA replication, and various cellular functions. Accurate com...
Hymenoptera has some of the highest diversity and number of individuals among insects. Many of these species potentially play key roles as food source...
Accumulating evidence suggests that a wide variety of cell deaths are deeply involved in cancer immunity. However, their roles in glioma have not been...