Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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Showing 1198-1218 of 11,636 articles
Neuroimmune mechanisms in PTSD: inflammatory heterogeneity, circuit dysfunction, and biomarker-based subtypes.

Post-traumatic stress disorder (PTSD) is characterized by exaggerated fear response, anxiety, hypera...

Jun 2026 42313200
Integrated bioinformatics and machine learning for shared diagnostic genes and mechanisms between periodontitis and psoriasis.

BACKGROUND: Periodontitis and psoriasis are two prevalent conditions that are bidirectionally associ...

(1)
Jun 2026 42313235
GENIE: A Two-Stage Interpretable Deep Learning Framework for Revealing the High-Order Genetic Interaction Network of Alzheimer's Disease.

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressive cognitive impa...

Jun 2026 42313600
SPADE: A Deep Learning Framework for Spatial Mapping and Quantitative Cell-Cell Interaction Inference.

Spatial transcriptomics (ST) enables the study of tissue architecture by resolving gene expression i...

Jun 2026 42314058
AI-Assisted Digital Single-Molecule Activity Tracker for Decoupling Intrinsic Heterogeneity from Photo-Oxidative Damage in High-Photon-Flux Enzymology.

Single-molecule enzymes serve as molecular motors for long-read sequencing, where laser tolerance un...

Jun 2026 42314063
Studying the Deep Evolution of Viruses in the Era of Artificial Intelligence Structure Prediction.

High mutation rates erode viral sequence similarity, obscuring deep evolutionary history. While prot...

Jun 2026 42314068
Mapping the TCR landscape: computational tools empowering translational immunology and therapy design.

T cell receptors (TCRs) are central to adaptive immunity, yet their vast sequence and structural div...

Jun 2026 42315254
Deep learning-guided engineering of SpuFz1 and rational miniaturization of ωRNA enables efficient genome editing.

Advancing the performance of programmable genome editing nucleases remains a key challenge in expand...

Jun 2026 42315520
Inferring translational efficiency from transcriptomes improves noncanonical neoantigen prioritization and cancer patient stratification.

Accurate assessment of protein translation is crucial for understanding disease variant functions, b...

Jun 2026 42310075
Genomic signatures of host adaptation in Pasteurella multocida from poultry, cattle, swine, and cats: insights from interpretable machine learning.

Pasteurella multocida is a major zoonotic pathogen causing fowl cholera and other animal-derived inf...

Jun 2026 42497796
E-InfertilityTest: Implementing an explainable AI framework for male infertility assessment.

Male infertility has emerged as a significant concern in modern society, with genetic defects as one...

(1)
Jun 2026 42335657
Machine learning algorithms develop a tumor-educated platelets-related gene signature to predict colorectal cancer prognosis and therapy response.

Tumor-educated platelets (TEPs) have recently emerged as an important component of liquid biopsy, ye...

(1)
Jun 2026 42375537
Weight-Controllable Biobarcode Probes for Multi-input Breast Cancer Diagnosis.

DNA-based molecular classifiers have emerged as a promising strategy for precise cancer diagnosis, o...

Jun 2026 42306980
A Phase-Resolved Geometric Deep Learning Framework Maps Structural Determinants of Disease-Associated Protein Aggregation and Guides Suppressor Design.

Protein aggregation drives major neurodegenerative diseases, yet most computational predictors colla...

Jun 2026 42307331
Novel aptamers targeting heparan sulfate for delivery of RNA therapeutics in Alzheimer's disease.

Heparan sulfate (HS) proteoglycans are abundant, sulfation-patterned glycosaminoglycans on brain cel...

Jun 2026 42309126
Hybrid deep learning-based rapid broad-Spectrum antimicrobial susceptibility prediction from whole-genome assemblies.

Antimicrobial resistance (AMR) is a global public health threat. Mortality and poor treatment outcom...

Jun 2026 42309394
Single-cell transcriptomic analysis reveals the T lymphocyte microenvironment and identifies HOPX as a hub gene in membranous nephropathy.

BACKGROUND: Membranous nephropathy (MN) is an autoimmune disease characterized by immune complex dep...

(1)
Jun 2026 42309401
Guide RNA reprogramming facilitates minimized tracrRNA-dependent off-target and versatile CRISPR/Cas9 engineering.

While innovative, current CRISPR-Cas9 systems face safety concerns and practical hurdles, notably se...

Jun 2026 42309993
Proteomic Mendelian randomization and machine learning reveal causal plasma biomarkers in cardiorenal comorbidity.

BACKGROUND: Chronic kidney disease (CKD) significantly increases the risk of coronary artery disease...

(1)
Jun 2026 42299131
Machine Diagnostics and Machine Phenotyping of Migraine: A HUNT Study.

BACKGROUND AND OBJECTIVES: In the absence of biomarkers, the true biological footprint of migraine r...

(1)
Jun 2026 42302223
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