Genetics

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KIF23 in disease pathogenesis and its therapeutic and diagnostic potential.

BACKGROUND: Kinesin family member 23 (KIF23) is a microtubule-dependent motor protein essential for ...

May 2026 42178466
Exploring the oasis of plant genomes: From genetic variations to function and beyond.

For decades, plant geneticists have been striving to elucidate the biological mechanisms by which ge...

May 2026 42177617
Identification and Validation of Glycosylation-Related Biomarkers in the Hippocampus for Alzheimer's Disease Diagnosis and Drug Repurposing.

As a crucial type of post-translational modification, glycosylation plays a fundamental role in main...

(2)
May 2026 42178007
High-throughput design of defined microbial consortia for crop protection.

BACKGROUND: Synthetic microbial communities (SynComs) are changing the mechanism of crop protection ...

May 2026 41496592
Spiking Neural Membrane Systems with Temporal Coding.

Spiking neural P systems (SNP systems) are a type of neuromorphic membrane computing models abstract...

(1)
May 2026 42175604
10 years of CRISPR/CAS genomic engineering in Yarrowia lipolytica.

Yarrowia lipolytica is a versatile cell factory widely used in bioprocesses for producing lipids, or...

May 2026 42176206
Overcoming Shortcut Learning in RNA-Small Molecule Modeling via Bias-Matched Decoys and Structure-Aware Network Design.

Targeting RNA with small molecules represents a promising frontier in drug discovery, yet current co...

(1)
May 2026 42176352
Molecular and spatial differences in the tumor microenvironment of high-grade serous ovarian cancers with short versus long-term survival.

OBJECTIVE: Survival of patients diagnosed with advanced-stage high-grade serous ovarian cancer (HGSO...

(2)
May 2026 42176362
Explainable machine learning identifies features and thresholds predictive of immunotherapy response.

The identification of reliable predictors for immunotherapy response remains a critical challenge in...

May 2026 42177174
Coformer: a deep learning-based framework for cross-environment and multi-year cotton phenotype prediction and interpretation.

Accurate prediction of key agronomic traits in cotton is crucial for advancing its genetic improveme...

May 2026 42177568
Leveraging Large Language Models to Identify Lung Cancer Patients with Unregistered World Trade Center Disaster Exposure.

OBJECTIVE: Leveraging large language models, we identified an unregistered subpopulation of individu...

(1)
May 2026 42168810
Identification of diagnostic markers for diabetic kidney disease by weighted gene co‑expression network analysis and machine learning.

Diabetic kidney disease (DKD) represents a major complication associated with diabetes mellitus, not...

(1)
May 2026 42169644
Epigenetic research methods and animal models for intervertebral disc degeneration (Review).

Intervertebral disc degeneration (IVDD) is increasingly recognized as a systemic collapse of the epi...

(2)
May 2026 42169659
Curcumin alleviates depression-aggravated psoriasis by targeting MMP9-regulated apoptotic pathways.

Depression and psoriasis are highly comorbid, yet their shared molecular mechanisms remain poorly un...

(1)
May 2026 42231964
Whole-genome sequencing revealed the genomic origin of Solanum demissum Lindl., a Mexican hexaploid wild potato species.

BACKGROUND: Solanum demissum Lindl. (2n = 6x = 72) is the most popular wild species in potato breedi...

May 2026 42174426
Early detection of gastric cancer with the assistance of cell-free DNA fragmentomics.

BACKGROUND: Gastric cancer remains one of the most prevalent malignancies globally. As early-stage g...

May 2026 42174634
Mechanisms linking primary biliary cholangitis and osteoporosis: A combined clinical and molecular analysis.

Primary biliary cholangitis (PBC) is an immune-mediated cholestatic liver disease, and osteoporosis ...

May 2026 42175405
Survival prediction of colorectal cancer using 101 machine learning methods based on immune-related genes: A machine learning study.

Colorectal cancer (CRC) is characterized by high incidence and mortality rates. Early identification...

May 2026 42175499
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