Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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DeepCBA: A deep learning framework for gene expression prediction in maize based on DNA sequences and chromatin interactions.

Chromatin interactions create spatial proximity between distal regulatory elements and target genes ...

Integrating genomics, phenomics, and deep learning improves the predictive ability for Fusarium head blight-related traits in winter wheat.

Fusarium head blight (FHB) remains one of the most destructive diseases of wheat (Triticum aestivum ...

Time-Series MR Images Identifying Complete Response to Neoadjuvant Chemotherapy in Breast Cancer Using a Deep Learning Approach.

BACKGROUND: Pathological complete response (pCR) is an essential criterion for adjusting follow-up t...

Unraveling the genetic and molecular landscape of sepsis and acute kidney injury: A comprehensive GWAS and machine learning approach.

OBJECTIVES: This study aimed to explore the underlying mechanisms of sepsis and acute kidney injury ...

Prediction of adverse drug reactions due to genetic predisposition using deep neural networks.

Drug development is a long and costly process, often limited by the toxicity and adverse drug reacti...

A Kernelized Classification Approach for Cancer Recognition Using Markovian Analysis of DNA Structure Patterns as Feature Mining.

Nucleotide-based molecules called DNA and RNA are essential for several biological processes that af...

Machine learning for the identification of neoantigen-reactive CD8 + T cells in gastrointestinal cancer using single-cell sequencing.

BACKGROUND: It appears that tumour-infiltrating neoantigen-reactive CD8 + T (Neo T) cells are the pr...

NmTHC: a hybrid error correction method based on a generative neural machine translation model with transfer learning.

BACKGROUNDS: The single-pass long reads generated by third-generation sequencing technology exhibit ...

Developing a prognostic model using machine learning for disulfidptosis related lncRNA in lung adenocarcinoma.

Disulfidptosis represents a novel cell death mechanism triggered by disulfide stress, with potential...

Protein function annotation and virulence factor identification of Klebsiella pneumoniae genome by multiple machine learning models.

Klebsiella pneumoniae is a type of Gram-negative bacterium which can cause a range of infections in ...

Multispectral 3D DNA Machine Combined with Multimodal Machine Learning for Noninvasive Precise Diagnosis of Bladder Cancer.

Extracellular vesicle (EV) molecular phenotyping offers enormous opportunities for cancer diagnostic...

Nonlinear classifiers for wet-neuromorphic computing using gene regulatory neural network.

The gene regulatory network (GRN) of biological cells governs a number of key functionalities that e...

Identification of Family-Specific Features in Cas9 and Cas12 Proteins: A Machine Learning Approach Using Complete Protein Feature Spectrum.

The recent development of CRISPR-Cas technology holds promise to correct gene-level defects for gene...

Functional Neural Networks for High-Dimensional Genetic Data Analysis.

Artificial intelligence (AI) is a thriving research field with many successful applications in areas...

PPRTGI: A Personalized PageRank Graph Neural Network for TF-Target Gene Interaction Detection.

Transcription factors (TFs) regulation is required for the vast majority of biological processes in ...

MAHyNet: Parallel Hybrid Network for RNA-Protein Binding Sites Prediction Based on Multi-Head Attention and Expectation Pooling.

RNA-binding proteins (RBPs) can regulate biological functions by interacting with specific RNAs, and...

GenCoder: A Novel Convolutional Neural Network Based Autoencoder for Genomic Sequence Data Compression.

Revolutionary advances in DNA sequencing technologies fundamentally change the nature of genomics. T...

A comprehensive survey on the use of deep learning techniques in glioblastoma.

Glioblastoma, characterized as a grade 4 astrocytoma, stands out as the most aggressive brain tumor,...

Optimizing clinico-genomic disease prediction across ancestries: a machine learning strategy with Pareto improvement.

BACKGROUND: Accurate prediction of an individual's predisposition to diseases is vital for preventiv...

A novel framework based on explainable AI and genetic algorithms for designing neurological medicines.

The advent of the fourth industrial revolution, characterized by artificial intelligence (AI) as its...

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