Gastroenterology

GERD

Latest AI and machine learning research in gerd for healthcare professionals.

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Artificial Intelligence-Driven Multi-Omics Analysis Reveals Hydroxytyrosol Targeting of the TXNIP-NLRP3 Inflammasome Axis in Traumatic Brain Injury.

Traumatic brain injury (TBI) induces secondary neuroinflammation driven by oxidative stress, inflammasome activation, and immune remodeling, yet specific mechanism-guided pharmacological interventions remain limited. This study established an artificial intelligence (AI)-integrated network pharmacology and multi-omics framework to evaluate whether hydroxytyrosol (HT), an olive-derived natural poly...

Sep 5 2026 42700807

A machine learning-based framework for analyzing mitral regurgitation-related signal patterns from photoplethysmography.

OBJECTIVES: This study investigates the feasibility of using photoplethysmography (PPG) signals for supporting mitral regurgitation (MR) assessment and monitoring using machine learning techniques. METHODS: MR occurs when blood flows backward from the left ventricle to the left atrium due to mitral valve insufficiency. Although echocardiography is the standard diagnostic method, it requires expert...

Sep 4 2026 42695339
Ultra-High-Resolution Quantum Dot Microdisplays Fabricated via Microvia Electrostatic Adsorption Self-Assembly.

The rapid advancement of artificial intelligence drives advances in microdisplays for smart wearables and near-eye applications. This imposes extremel...

Sep 3 2026 42691362
Natural language processing for detecting endoscopy-related adverse events in free-text procedure reports at a tertiary referral centre in Türkiye: a 10-year retrospective diagnostic accuracy study.

OBJECTIVES: Automated surveillance of endoscopy-related adverse events (AEs) from non-English free-text reports remains insufficiently evaluated. We c...

Sep 3 2026 42692516
Protein-protein interactions as therapeutic targets in breast cancer: integrated computational and experimental advances, mechanisms and clinical translation.

Breast cancer is a highly heterogeneous malignant tumour, whose initiation and progression are closely associated with aberrant rewiring of protein-pr...

Sep 2 2026 42684521
Cough Hypersensitivity in Gastroesophageal Reflux-Induced Chronic Cough: Insights from Reflux Monitoring and High-Resolution Manometry.

BACKGROUND: Cough hypersensitivity contributes to the heterogeneity of gastroesophageal reflux-induced chronic cough (GERC), but its associated factor...

Sep 2 2026 42686877
Dedicated Endoscopy for Barrett's Oesophagus With Higher Dysplasia Yield May Reduce Seattle Protocol Biopsies: Results From UK Multicentre Study.

BACKGROUND: Dedicated service for Barrett's oesophagus (BO) surveillance may be more effective than conventional service, according to some single cen...

Sep 1 2026 42528176
Computational discovery of HIF-1α/VHL protein-protein interaction inhibitors for hypoxic cell protection.

The HIF-1α/VHL protein-protein interaction regulates cellular hypoxic adaptation. Targeting this PPI offers therapeutic potential for ischemia, yet th...

Aug 28 2026 42665764
Exploration of acetylation-related biomarkers in osteoarthritis through bioinformatics analysis.

Osteoarthritis (OA) is characterized as a chronic degenerative disorder affecting the joints. A growing body of evidence indicates that acetylation ma...

Aug 28 2026 42664217
Predictive Models of Pregnancy Based on Male Partner Data From a Preconception Cohort Study.

BACKGROUND: Male factors contribute to approximately 50% of couple infertility, yet few studies have used machine learning with comprehensive male par...

Aug 27 2026 42661451
Completely free-breathing cardiac MRI using deep learning reconstruction reduces sedation and scan time in children.

BACKGROUND: Traditional cardiac magnetic resonance (CMR) imaging scan times are long and require breath-holds, often necessitating intubation and mech...

Aug 27 2026 42658264
iDCF: Interpretable deconvolution of cell fractions via biologically-informed deep learning using scRNA-seq data.

Precise resolution of cellular heterogeneity within complex tissues is fundamental to deciphering disease etiologies from bulk transcriptomic profiles...

Aug 27 2026 42658881
EndoVLM: A Vision-Language Assistant for Gastrointestinal Endoscopy.

Gastrointestinal endoscopy generates extensive high-resolution video data, posing significant challenges for efficient and accurate computer-aided dia...

Aug 26 2026 42649331
An integrated systems biology and machine learning framework for identifying potential biomarkers and pathways in autism spectrum disorder.

BACKGROUND: Autism spectrum disorders (ASD) are a group of neurodevelopmental disorders whose underlying molecular mechanisms and biological processes...

Aug 24 2026 42636188
Targeting GLS and LPIN2 in renal fibroblasts: potential therapeutic targets for kidney stone disease identified by integrated multi-omics analysis.

Kidney stones (KS) are a common urological condition, the aetiology of which remains incompletely understood. This study aimed to investigate the key ...

Aug 22 2026 42631750
Simulating Reality and Transforming Endoscopic Education-Lessons from Esophageal Dilation.

Although endoscopic training has traditionally relied on mentorship and procedural volume to assess proficiency, the major gastroenterology societies ...

Aug 21 2026 42629470
An interpretable multi-instance learning method for accurate differentiation of malignant and benign laryngeal lesions in laryngoscopy.

BACKGROUND: Laryngeal cancer is a significant global health issue with high mortality, and early diagnosis is critical for survival. Developing accura...

Aug 20 2026 42625011
[Reflections on surgical management strategies for locally advanced gastric cancer after neoadjuvant immunotherapy].

Neoadjuvant immunotherapy is reshaping the treatment landscape of locally advanced gastric cancer (GC). The central clinical challenge has expanded fr...

Aug 20 2026 42576506
CASP1 as a key autophagy-related gene in atherosclerosis: Identification by bioinformatics analysis and experimental validation.

OBJECTIVE: This study identified potential autophagy-related genes (ARGs) in atherosclerosis using bioinformatics strategies, aiming to explore novel ...

Aug 19 2026 42616740
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