Gastroenterology

GERD

Latest AI and machine learning research in gerd for healthcare professionals.

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Photoacoustic-ultrasound endoscopy for assessment of rectal cancer treatment response: A prospective study with T2-weighted MRI radiomics comparison.

Accurate identification of pathological complete response (pCR) following neoadjuvant chemoradiotherapy for locally advanced rectal cancer (LARC) is critical for non-operative "watch-and-wait" strategies. In this study, we evaluated whether co-registered acoustic resolution photoacoustic microscopy and ultrasound (ARPAM-US) endoscopy with deep learning could better identify pCR than T2-weighted MR...

May 16 2026 42232466

PythiaStudio: a one-stop protein engineering platform powered by Pythia model suite.

Predicting how mutations affect protein stability and protein-protein binding affinity is crucial for protein engineering and drug development. Although several computational tools have been developed for these tasks, they often require specialized expertise and are difficult to integrate into unified workflows. Here, we present PythiaStudio (https://pythiastudio.wulab.xyz), a comprehensive web pl...

May 15 2026 42136527
Integrative bioinformatics and machine learning reveal an association of LTF and MMP8 with systemic inflammation and lung injury.

BACKGROUND: Acute lung injury and its severe form, acute respiratory distress syndrome (ARDS), represent life-threatening conditions with high mortali...

May 15 2026 42141451
Machine learning-driven identification of circulating biomarkers and therapeutic compounds for diabetic retinopathy.

BACKGROUND: Diabetic retinopathy (DR) is a major cause of severe visual impairment, where early diagnosis and intervention are crucial to prevent irre...

May 14 2026 42129911
Machine learning-based analysis of the relationship between brain lesion sites and swallowing and cognitive functions in stroke patients.

Stroke-related dysphagia is influenced by brain damage location and cognitive impairment, but its mechanisms remain unclear. In this study, we aimed t...

May 14 2026 42135376
Wearable Sensors for Monitoring Neurogenic Dysphagia: A Scoping Review.

Neurological disorders, such as Parkinson's disease and stroke, often lead to neurogenic dysphagia, a swallowing disorder that compromises nutrition a...

May 13 2026 42127994
Shaping the future of postoperative recurrence in Crohn's disease: personalised approaches with AI-enabled imaging and multi-omics.

Postoperative recurrence (POR) is a major challenge in the long-term management of Crohn's disease (CD), affecting up to 70% of patients within the fi...

May 12 2026 41592952
Molecular Functions and Drug Prediction of MMP1 and TGFBR2 in Nasopharyngeal Carcinoma.

BACKGROUND: Nasopharyngeal carcinoma (NPC) is partially driven by epithelial-mesenchymal transition (EMT). We identified potential EMT-related biomark...

May 12 2026 42117405
Involved nodal versus elective neck radiotherapy (INVERT) for head and neck squamous cell carcinoma: a prospective phase II randomized controlled trial protocol.

BACKGROUND: Definitive chemoradiotherapy for head and neck squamous cell carcinomas (HNSCC) carries significant long-term toxicities, with elective ne...

May 11 2026 42116021
Molecular mechanisms linking cadmium chloride exposure to ankylosing spondylitis: an integrative network-based study.

Chronic cadmium chloride (CC) exposure is associated with diverse toxicological outcomes, yet its potential role in the pathogenesis of ankylosing spo...

May 11 2026 42113191
GATA3 mediates the cardioprotective effect of hydroxysafflor yellow a against septic cardiomyopathy: insights from integrated machine learning, WGCNA, and experimental validation.

UNLABELLED: Sepsis-induced cardiomyopathy represents a life-threatening complication arising from severe sepsis and septic shock. Hydroxysafflor yello...

May 9 2026 42117033
Artificial intelligence-driven rational design and optimization of a potent terpenoid-derived PCSK9 inhibitor.

Hypercholesterolemia is a pivotal risk factor for cardiovascular diseases, and its effective management is critical to reducing cardiovascular event i...

May 9 2026 42105138
Electronics-free soft robotic minitablet for on-demand gastric molecular sensing and diagnostics in vivo.

Real-time biomarker sensing and molecular sampling in the stomach can transform how gastrointestinal disorders are diagnosed and managed-yet integrati...

May 8 2026 42102190
Generative chromoendoscopy for gastric neoplasms: A multicenter prospective study.

BACKGROUND AND STUDY AIMS: Generative indigo carmine chromoendoscopy (generative chromoendoscopy), produced using deep learning-based synthetic image ...

May 8 2026 42103307
Machine learning-based transcriptomic analysis of differentially expressed genes in the epithelium and stroma of keratoconus.

BACKGROUND: This study was conducted to delineate layer-specific transcriptomic alterations in the keratoconus (KC) epithelium and stroma and to ident...

May 8 2026 42104443
PSMa: Learning Protein Surface Representations with Physicochemical Masked Autoencoders.

Protein modeling has largely centered on sequence representations, leaving the geometry and physicochemical context of molecular surfaces underused. W...

May 6 2026 42090297
Development and validation of a real-time AI model for differentiating benign and malignant gastric ulcers : a multicenter retrospective study.

AIM: To develop and validate a deep learning-based AI system for the dynamic, real-time differentiation of benign and malignant gastric ulcers during ...

May 4 2026 42082915
CAD-SEL: A dual-modal colonoscopy dataset of subepithelial lesion.

Subepithelial lesions (SELs) of the gastrointestinal tract encompass a heterogeneous spectrum of histology, ranging from benign to malignant. Their de...

May 4 2026 42071022
Impact of Artificial Intelligence-Assisted Endoscopy on Screening for Upper Gastrointestinal Cancer in a Large-Scale Health Screening Facility.

OBJECTIVES: Artificial intelligence (AI)-assisted endoscopy has been developed for the early detection of upper gastrointestinal cancer; however, its ...

May 1 2026 42067512
Artificial Intelligence-Based Analysis of Laparoscopic Imaging for Intraoperative Surgical Decision Support.

Across surgical specialties, minimally invasive (laparoscopic) surgery has become a standard technique, as it is associated with less trauma, reduced ...

May 1 2026 42067514
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