Gastroenterology

GERD

Latest AI and machine learning research in gerd for healthcare professionals.

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Computational Drug Repurposing for Alzheimer's Disease via Sheaf Theoretic Population-Scale Analysis of snRNA-Seq Data.

Single-cell and single-nucleus RNA sequencing are used to reveal heterogeneity in cells, showing a growing potential for precision and personalized medicine. Nevertheless, sustainable drug discovery must be based on a population-level understanding of molecular mechanisms, which calls for a population-scale analysis of this data. This work introduces a sequential target-drug selection model for dr...

Feb 16 2026 41697185

Small-bowel capsule endoscopy - from clinic to couch: time to go green?

PURPOSE OF REVIEW: Small-bowel capsule endoscopy (SBCE) has transformed small-intestine diagnostics by enabling direct, noninvasive mucosal visualization. As healthcare systems increasingly prioritize value-based and sustainable care, this review explores recent advances in SBCE, focusing on home-delivery models, telemedicine, artificial intelligence (AI), and environmental impact. RECENT FINDINGS...

Feb 16 2026 41691528
Predicting the magnitude of risk for non-curative endoscopic submucosal dissection in superficial esophageal cancer using explainable artificial intelligence.

BACKGROUND: Endoscopic submucosal dissection (ESD) serves as a critical treatment modality for superficial esophageal cancer. However, non-curative re...

Feb 15 2026 41695917
Deep learning in lower gastrointestinal cancer detection: Advances in endoscopic, radiologic, and histopathologic diagnostics.

Gastrointestinal (GI) cancers, particularly colorectal cancer, continue to be a major contributor to global cancer-related morbidity and mortality. De...

Feb 15 2026 41695919
Predicting vesicoureteral reflux outcomes using artificial intelligence: A critical appraisal using APPRAISE-AI.

Vesicoureteral reflux (VUR) is a common congenital urinary tract anomaly in children, associated with recurrent urinary tract infections (UTIs) and lo...

Feb 13 2026 41686838
PlantCTCIP: Chromatin Interaction Prediction Using Convolutional Neural Network and Transformer in Plants.

Chromatin interactions establish spatial proximity between distant regulatory elements and their target genes, significantly influencing gene expressi...

Feb 12 2026 41677071
Outcomes of Artificial Intelligence Enhanced Colonoscopy in a Tertiary Clinical Setting.

BACKGROUND AND AIMS: Colonoscopies reduce colorectal cancer incidence and mortality, but challenges remain in detecting all precancerous lesions. Oper...

Feb 12 2026 41677150
Establishment of insulin resistance-related ten-gene signature in endometrial cancer and identification of ACTL8 as a prognostic and immunological biomarker.

BACKGROUND: Endometrial cancer (EC) is a common gynecological tumor. Insulin resistance (IR) increases the risk of EC. However, the common molecular b...

Feb 11 2026 41670819
Infectious disease diagnosis by artificial intelligence (AI): Differences in patient backgrounds and symptoms between antigen test positives and novel AI-powered pharyngeal endoscopy test positives.

This study aimed to identify differences in patient background and symptoms between individuals who tested positive using conventional rapid antigen (...

Feb 11 2026 41671230
Efficacy of artificial intelligence-assisted upper gastrointestinal endoscopy for neoplasm detection: a systematic review and meta-analysis of randomized controlled trials.

BACKGROUND AND AIMS: EGD remains the primary diagnostic modality for evaluating lesions of the upper gastrointestinal (UGI) tract. This meta-analysis ...

Feb 10 2026 41672109
Identification of mitochondrial dysfunction-related biomarkers and immune infiltration in liver ischemia-reperfusion injury via integrated bioinformatics and machine learning.

BACKGROUND: Mitochondrial dysfunction contributes to the pathogenesis of multiple diseases. This study explores the involvement of mitochondrial dysfu...

Feb 10 2026 41678948
Artificial Intelligence for Gastroenterology Practice: A Modified Delphi Consensus.

BACKGROUND: The American College of Gastroenterology (ACG) assembled a multidisciplinary task force to evaluate the current state and future direction...

Feb 10 2026 41665234
Development and validation of a prognosis model for low-grade gliomas based on metabolic gene risk scoring and immune microenvironment interaction.

PURPOSE: Low-grade gliomas(LGGs) show significant clinical and molecular heterogeneity, complicating progression prediction with conventional indicato...

Feb 10 2026 41665790
HLA-DPA1 as a diagnostic biomarker differentiating early- and late-onset preeclampsia.

The occurrence and development of a wide range of preeclampsia (PE), especially early-onset preeclampsia (EOPE), is closely associated with the immune...

Feb 10 2026 41667698
XL-MSDigger: a deep learning-based, versatile solution for cross-linking mass spectrometry.

Cross-linking mass spectrometry (XL-MS) technology plays an important role in protein structure and protein-protein interaction (PPI) studies. However...

Feb 10 2026 41663436
Randomized controlled trials in valvular heart disease: the evolving role of multimodality imaging.

Valvular heart disease represents a significant global health burden, with an estimated prevalence of 2.5% in high-income countries and projected incr...

Feb 9 2026 41365324
MAGIN-GO: Protein function prediction based on dual graph neural networks and gene ontology structure.

Proteins are fundamental to the execution of biological activities, and the accurate prediction of their functions is of paramount importance for prot...

Feb 9 2026 41662346
Targeting the MPO/LCN2/GMPPB axis in IBS-depression comorbidity: Integrated multi-omics and bidirectional network pharmacology for precision diagnostics and therapeutics.

BACKGROUND: Irritable Bowel Syndrome (IBS) and Major Depressive Disorder (MDD) exhibit high comorbidity, driven by dysregulation of gut-brain axis int...

Feb 8 2026 41678889
Machine learning-driven computational drug repurposing to identify new tubulin inhibitors against cancer.

Tubulin is a validated anticancer target, yet the clinical translation of colchicine-binding site inhibitors remains limited by toxicity and resistanc...

Feb 8 2026 41689974
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