Ophthalmology

Glaucoma

Latest AI and machine learning research in glaucoma for healthcare professionals.

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Transient but significant visual field defects after robot-assisted laparoscopic radical prostatectomy in deep tRendelenburg position.

BACKGROUND: Robot-assisted laparoscopic radical prostatectomy (RALP) is a minimally invasive surgical procedure for prostate cancer. During RALP, the patient must be in a steep Trendelenburg (head-down) position, which leads to a significant increase in intraocular pressure (IOP). The association of RALP with visual field sensitivity, however, has not been prospectively studied. The purpose of thi...

Apr 23 2015 25906167

CHIASM: A Self-Supervised Visual Field Encoder for Neuro-Ophthalmology

Background: Artificial intelligence (AI) systems for glaucoma diagnosis and prognostication from visual fields (VF) are under active development, yet do not audit for vertical-meridian-respecting field loss - known sequelae of stroke, hemorrhage, and neoplasm. We developed a self-supervised encoder of automated perimetry that learns anatomically interpretable VF structure without labels, and evalu...

OptiModNet: A UNet-Transformer Hybrid with Grouped-Query and Channel Attention for Optic Disc and Cup Segmentation

Precise segmentation of the optic disc and cup is critical for the early detection and diagnosis of glaucoma. However, achieving consistently high per...

Aug 19 2026 2608.18516v1
Optic Disc Segmentation in Fundus Images: From Classical Image Processing and Deformable Models to Modern AI

Accurate localization and segmentation of the optic disc (OD) are important for retinal image analysis and glaucoma assessment, yet remain challenging...

Aug 18 2026 2608.18367v1
Population Structure Analysis of an Inbred Population using Quantitative Shape Phenotyping from Stereo Retinal Photographs

The population structure of an inbred population of 781 people on Norfolk Island in the Pacific, 318 of which are descendants of the original Mutineer...

Aug 16 2026 2608.15471v1
Balanced Soft mixture-of-expert model for Glaucoma Detection

Glaucoma is a group of eye diseases that damage the optic nerve, often caused by elevated intraocular pressure. It is a leading cause of irreversible ...

Jul 28 2026 2607.25324v1
CANDOR: Chance-Calibrated Discordance in Frozen Foundation Encoders

Frozen encoders are chosen by how well a lightweight head reads a finding from their features, not whether the geometry separates it. Nearest-neighbor...

Jul 20 2026 2607.18451v1
Luminosity-Adaptive Contrast Enhancement Using CLAHE for Retinal Fundus Images with Quantitative Validation and Comparative Analysis

Background: Retinal fundus imaging is central to the early diagnosis of sight-threatening conditions including diabetic retinopathy, glaucoma, and ret...

Jul 20 2026 2607.17691v1
Integrating Neural Encoders in Bayesian Generalized Linear Mixed Models for Multimodal Data

Scalable Bayesian inference for generalized linear mixed models (GLMMs) provides uncertainty-aware analysis of correlated longitudinal data, but exist...

Jul 6 2026 2607.04647v1
GlaKG: A Biomarker-Centric Fundus Knowledge Graph for Explainable Glaucoma Diagnosis and Risk Assessment

Glaucoma is a leading cause of irreversible blindness worldwide, yet most automated diagnosis systems rely on opaque deep-learning models that offer l...

Jul 6 2026 2607.04673v1
Beyond Point Estimates for Glaucoma Visual Field Forecasting with Diffusion Models

Forecasting visual fields (VFs) is critical for personalized monitoring and treatment planning in glaucoma. This is inherently uncertain due to hetero...

Jun 29 2026 2606.30417v1
Clinically aligned rationale generation for glaucoma subtype classification via a knowledge-distilled language model

Automated glaucoma subtype classification from clinical notes remains clinically unactionable without subspecialty-aligned explanations supporting cli...

Can Demographic Information Be Reduced in Retinal Fundus Images While Preserving Glaucoma-Relevant Features?

Purpose: To determine whether disease-aware adversarial perturbations can reduce demographic recoverability encoded in color fundus photographs (CFPs)...

Extraction of Glaucoma Diagnosis, Type, and Severity from Clinical Notes using Secure Cloud-based Large Language Models

Purpose: To evaluate the performance of secure cloud-based large language models (LLMs) in extracting glaucoma diagnosis, type, and severity from free...

GLLaucoMed: A Secure LLM-Powered Agentic Workflow for Automated Medication Extraction from Free-Text Glaucoma Clinical Notes

Purpose: To evaluate the efficacy of large language models (LLMs) in extracting medication-related information from glaucoma clinical notes in the ele...

Ellipse Meets Bit-Planes: A Novel Approach to RNFL based Glaucoma Detection Using Advanced Image Processing and Deep Learning

This work proposes an integrated pipeline for automatic glaucoma detection method from easily available colour fundas images based on an adaptive algo...

Jun 14 2026 2606.15772v1
DiffSight-Former: Modeling Structural Differences and Temporal Dynamics for Glaucoma Progression Prediction

Glaucoma is a leading cause of irreversible blindness worldwide, and early detection from fundus images is critical for effective disease management. ...

Jun 8 2026 2606.09140v1
Neovascular Glaucoma at a Tertiary Centre in Finland, 2008-2024: A Retrospective Cohort Study

Background/Aims: Neovascular glaucoma (NVG) is an aggressive secondary glaucoma with limited longitudinal data. This study reports the aetiologies, tr...

Developing and Evaluating Deep Learning Approaches for Visual Field Denoising in Glaucoma

Purpose To investigate the relative efficacy of nine distinct visual field (VF) denoising artificial intelligence (AI) methods and a pathology-aware A...

Deriving OCT-Equivalent Retinal Nerve Fiber Layer Thickness Maps from Fundus Photographs with Deep Learning Improves Glaucoma Diagnosis

Purpose: To develop and evaluate a deep learning model that predicts optical coherence tomography (OCT)-equivalent retinal nerve fiber layer thickness...

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