Hematology

Latest AI and machine learning research in hematology for healthcare professionals.

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AI-enabled Spatial Profiling of Circulating Tumor-Immune Ecosystems Predicts Patient Outcomes Across Cancers

Circulating tumor cells (CTCs) and immune cells form dynamic multicellular ecosystems in blood, but their spatial organization and clinical relevance have not been systematically characterized. We developed the Cell and Cluster Identification Program (CCIP), an artificial intelligence-based framework that analyzes routine multiplex immunofluorescence blood scans to segment cells, identify CTCs and...

Dual-Correlation Hypergraph Network for Unaligned RGBT Video Object Detection and A Large-scale Benchmark

RGB-Thermal (RGBT) Video Object Detection (VOD) has gained significant traction due to its ability to overcome the limitations of conventional RGB-based VOD under challenging conditions. However, spatial misalignment commonly exists between RGBT image pairs. To address this, we propose a Dual-Correlation Hypergraph Network (DHNet) that captures high-dimensional complementary information by explici...

Jul 9 2026 2607.08191v1
Determinants of Blood Group Antigen Expression and Prediction of Phenotypes by Machine Learning

Blood group antigens, defined by epitopes on the erythrocyte surface, are central to transfusion safety and maternal-fetal compatibility. While the ge...

Emergency Department Presenting Concerns Among Admissions With Hypercapnia: A Retrospective NLP Study of MIMIC-IV

Background Hypercapnia may indicate a primary ventilatory syndrome, a complication of another illness, or an epiphenomenon of severe disease. The pres...

AI-Driven Precision Nutrition for Predicting Iron Deficiency Using Genomics, Polygenic Risk Scores, Dietary Patterns, and Personalized Dietary Recommendations

Background: Iron Deficiency Anemia (IDA) is one of the most prevalent nutritional disorders globally and a leading cause of Disability Adjusted Life Y...

Association between glycated hemoglobin A1c and automated abdominal aortic calcification: the UK Biobank Imaging Study

Background: Poor glycemic control is associated with cardiovascular disease (CVD) risk. However, it is unknown whether glycemic control is related to ...

LILAC: Layer-Wise Independent LoRAs and Cascaded Conditioning for Multi-Concept Customization of Diffusion Models

Personalizing text-to-image diffusion models to render several specific subjects in a coherent image remains challenging: the model must preserve each...

Jul 6 2026 2607.04801v1
LeukocyteCount: Automatic Identification and Counting for leukocytes using Deep Learning

Diagnosing and monitoring diseases frequently involves the analysis of human biological samples, with blood analysis being pivotal. Specifically, leuk...

Jul 5 2026 2607.04486v1
Deciphering the Tumor Microenvironment: An Integrated Single-Cell RNA-Seq and AI Framework for Novel Biomarker and Therapeutic Target Discovery in Melanoma

Background: Melanoma represents a highly immunogenic and therapeutically challenging malignancy. The complex cellular ecosystem of the tumor microenvi...

Safe Redosable Low-Immunogenic In Vivo CAR-T Therapy for B Cell Malignancies and Solid Tumors

In vivo CAR-T cell therapy eliminates manufacturing complexities associated with ex vivo autologous approaches, but safety concerns have limited adopt...

Integrating dynamic nomogram and machine learning for personalized disability prediction in elderly cardiometabolic multimorbidity: routine blood markers and mental health

Abstract Background: Disability prediction in elderly with cardiometabolic multimorbidity (CMM) is limited. We developed a dynamic nomogram and addres...

Can a Tissue-derived Progression Signature Accurately Predict Colorectal Cancer Stage Transitions in Blood?

Abstract. Colorectal cancer (CRC) is challenging to track because its molecular changes are very complex as the disease progresses, creating significa...

eRNAformer enables genome-wide de novo mapping of enhancer-derived RNA loci

Enhancer-derived RNAs (eRNAs) are critical regulators of gene transcription, yet their genome-wide annotation remains challenging. Here, we present eR...

Development and Validation of Machine Learning Models for Predicting Initiation of Emergency Dialysis in Advanced Chronic Kidney Disease

BackgroundInitiation of emergency dialysis, often requiring temporary catheter owing to unprepared definitive vascular access, is associated with infe...

Multilingual Hematology Visual Question Answering Dataset

Vision Language Models (VLMs) have shown promising capabilities in medical image analysis by jointly understanding visual and textual information for ...

Jun 24 2026 2606.25246v1
Cumulative Metabolic Exposure to Hyperglycemia and Risk of Cardiovascular and Limb Events in Peripheral Artery Disease

Background: Although diabetes is a potent risk factor for the development of peripheral artery disease (PAD), the effect of cumulative metabolic expos...

EventHorizon: A Foundation Model for Clinical Flow Cytometry

Flow cytometry is an essential tool for diagnosis of hematologic malignancies, but existing clinical workflows are highly dependent on expert manual i...

Machine learning evaluation of gene expression-based ALS subtypes across brain and blood tissues

The clinical and molecular heterogeneity observed in amyotrophic lateral sclerosis (ALS) presents a challenge for diagnosis, prognosis, and treatment....

Buffered sweat microfluidics with AI-enabled translation for clinically actionable blood urea estimation and renal risk stratification

Kidney-function assessment relies on blood urea as a clinically informative metabolic marker; however, its dependence on venipuncture and centralised ...

QG-MIL: A Gated Transformer Aggregator for Domain-Agnostic Multiple Instance Learning in Medical Imaging

Attention-based Multiple Instance Learning aggregators in medical imaging are prone to attention concentration, producing overconfident and unstable p...

Jun 18 2026 2606.20027v1
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