Hematology

Hemophilia

Latest AI and machine learning research in hemophilia for healthcare professionals.

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Establishment of extensive artificial intelligence models for kinase inhibitor prediction: Identification of novel PDGFRB inhibitors.

Identifying hit compounds is an important step in drug development. Unfortunately, this process cont...

Mar 2023 36878123
Strategy toward Kinase-Selective Drug Discovery.

Kinase drug selectivity is the ground challenge in cancer research. Due to the structurally similar ...

Feb 2023 36815703
Development, validation, and evaluation of a deep learning model to screen cyclin-dependent kinase 12 inhibitors in cancers.

Deep learning-based in silico alternatives have been demonstrated to be of significant importance in...

Feb 2023 36827953
A radiomics-based deep learning approach to predict progression free-survival after tyrosine kinase inhibitor therapy in non-small cell lung cancer.

BACKGROUND: The epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) are a firs...

Jan 2023 36670497
Deep learning for predicting the risk of immune checkpoint inhibitor-related pneumonitis in lung cancer.

AIM: To develop and validate a nomogram model that combines computed tomography (CT)-based radiologi...

Jan 2023 36914457
Molecular modeling of C1-inhibitor as SARS-CoV-2 target identified from the immune signatures of multiple tissues: An integrated bioinformatics study.

The expeditious transmission of the severe acute respiratory coronavirus 2 (SARS-CoV-2), a strain of...

Dec 2022 36517964
Generative deep learning enables the discovery of a potent and selective RIPK1 inhibitor.

The retrieval of hit/lead compounds with novel scaffolds during early drug development is an importa...

Nov 2022 36371441
Microfluidics guided by deep learning for cancer immunotherapy screening.

Immunocyte infiltration and cytotoxicity play critical roles in both inflammation and immunotherapy....

Nov 2022 36343225
Discovery of novel SARS-CoV-2 3CL protease covalent inhibitors using deep learning-based screen.

SARS-CoV-2 3CL protease is one of the key targets for drug development against COVID-19. Most known ...

Oct 2022 36209629
The current role of artificial intelligence in hemophilia.

INTRODUCTION: The utilization of artificial intelligence (AI) in hemophilia is still in its early ph...

Aug 2022 35980129
Risk Factors Analysis of Surgical Infection Using Artificial Intelligence: A Single Center Study.

Surgical site infections (SSIs) have a major role in the evolution of medical care. Despite centuri...

Aug 2022 36011656
Deep learning for topical trend discovery in online discourse about Pre-Exposure Prophylaxis (PrEP).

Pre-Exposure Prophylaxis (PrEP) interventions are increasingly prevalent on social media. These data...

Aug 2022 35916950
Development of Lymphopenia during Therapy with Immune Checkpoint Inhibitors Is Associated with Poor Outcome in Metastatic Cutaneous Melanoma.

Predictive markers for immune checkpoint inhibitor (ICI) therapy are needed. Thus, baseline blood co...

Jul 2022 35805052
Anti-CRISPR prediction using deep learning reveals an inhibitor of Cas13b nucleases.

As part of the ongoing bacterial-phage arms race, CRISPR-Cas systems in bacteria clear invading phag...

May 2022 35649413
Deep compartment models: A deep learning approach for the reliable prediction of time-series data in pharmacokinetic modeling.

Nonlinear mixed effect (NLME) models are the gold standard for the analysis of patient response foll...

May 2022 38100092
An integrated network representation of multiple cancer-specific data for graph-based machine learning.

Genomic profiles of cancer cells provide valuable information on genetic alterations in cancer. Seve...

Apr 2022 35487924
DNA Input Classification by a Riboregulator-Based Cell-Free Perceptron.

The ability to recognize molecular patterns is essential for the continued survival of biological or...

Apr 2022 35381174
An imaging-based artificial intelligence model for non-invasive grading of hepatic venous pressure gradient in cirrhotic portal hypertension.

The hepatic venous pressure gradient (HVPG) is the gold standard for cirrhotic portal hypertension (...

Mar 2022 35492878
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