Hematology

Hemophilia

Latest AI and machine learning research in hemophilia for healthcare professionals.

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Showing 379-399 of 4,984 articles
Machine Learning Models Identify Inhibitors of New Delhi Metallo-β-lactamase.

The worldwide spread of the metallo-β-lactamases (MBL), especially New Delhi metallo-β-lactamase-1 (...

May 2024 38727192
Deep learning based digital pathology for predicting treatment response to first-line PD-1 blockade in advanced gastric cancer.

BACKGROUND: Advanced unresectable gastric cancer (GC) patients were previously treated with chemothe...

(1)
May 2024 38720336
Application of machine learning approaches for predicting hemophilia A severity.

BACKGROUND: Hemophilia A (HA) is an X-linked congenital bleeding disorder, which leads to deficiency...

May 2024 38718927
Reactivities of acrylamide warheads toward cysteine targets: a QM/ML approach to covalent inhibitor design.

Covalent inhibition offers many advantages over non-covalent inhibition, but covalent warhead reacti...

(2)
May 2024 38693331
Binding Mechanism of Inhibitors to BRD4 and BRD9 Decoded by Multiple Independent Molecular Dynamics Simulations and Deep Learning.

Bromodomain 4 and 9 (BRD4 and BRD9) have been regarded as important targets of drug designs in regar...

Apr 2024 38675678
Artificial intelligence for detection of effusion and lipo-hemarthrosis in X-rays and CT of the knee.

BACKGROUND: Traumatic knee injuries are challenging to diagnose accurately through radiography and t...

(2)
Apr 2024 38608501
Boosting Clear Cell Renal Carcinoma-Specific Drug Discovery Using a Deep Learning Algorithm and Single-Cell Analysis.

Clear cell renal carcinoma (ccRCC), the most common subtype of renal cell carcinoma, has the high he...

(1)
Apr 2024 38612943
Validated machine learning tools to distinguish immune checkpoint inhibitor, radiotherapy, COVID-19 and other infective pneumonitis.

BACKGROUND: Pneumonitis is a well-described, potentially disabling, or fatal adverse effect associat...

(3)
Apr 2024 38582181
Utilizing machine learning to identify nifuroxazide as an inhibitor of ubiquitin-specific protease 21 in a drug repositioning strategy.

Ubiquitin-specific protease (USP), an enzyme catalyzing protein deubiquitination, is involved in bio...

(2)
Mar 2024 38518599
PPII-AEAT: Prediction of protein-protein interaction inhibitors based on autoencoders with adversarial training.

Protein-protein interactions (PPIs) have shown increasing potential as novel drug targets. The desig...

(1)
Mar 2024 38503089
Digital pathology with artificial intelligence analysis provides insight to the efficacy of anti-fibrotic compounds in human 3D MASH model.

Metabolic dysfunction-associated steatohepatitis (MASH) is a severe liver disease characterized by l...

(2)
Mar 2024 38467661
Inflamed immune phenotype predicts favorable clinical outcomes of immune checkpoint inhibitor therapy across multiple cancer types.

BACKGROUND: The inflamed immune phenotype (IIP), defined by enrichment of tumor-infiltrating lymphoc...

(1)
Feb 2024 38355279
Inadequate Anti-Factor Xa Levels With Daily 40-mg Enoxaparin After Cardiac Surgery.

BACKGROUND: Cardiac surgery patients are at increased risk for venous thromboembolism (VTE). Prevent...

Feb 2024 39790376
Machine learning based on blood test biomarkers predicts fast progression in advanced NSCLC patients treated with immunotherapy.

OBJECTIVE: Fast progression (FP) represents a desperate situation for advanced non-small cell lung c...

Feb 2024 39886130
Unravelling the role of Sildenafil and SB204741 in suppressing fibrotic potential of peritoneal fibroblasts obtained from PD patients.

Peritoneal fibrosis (PF) results in technique failure in peritoneal dialysis (PD) patients. Periton...

(1)
Jan 2024 38322704
Effect of palladium(II) complexes on NorA efflux pump inhibition and resensitization of fluoroquinolone-resistant : and approach.

leads to diverse infections, and their treatment relies on the use of antibiotics. Nevertheless, th...

Jan 2024 38292858
Identification and validation of potential biomarkers for atrial fibrillation based on integrated bioinformatics analysis.

Globally, the most common form of arrhythmias is atrial fibrillation (AF), which causes severe morb...

Jan 2024 38274270
Assessing risk factors associated with breakthrough early post-traumatic seizures in patients receiving phenytoin prophylaxis.

OBJECTIVE: Post-traumatic seizure (PTS) is a well-known complication of traumatic brain injury (TBI)...

Jan 2024 38239322
Using deep learning and molecular dynamics simulations to unravel the regulation mechanism of peptides as noncompetitive inhibitor of xanthine oxidase.

Xanthine oxidase (XO) is a crucial enzyme in the development of hyperuricemia and gout. This study f...

(1)
Jan 2024 38168773
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