Infectious Disease

Hepatitis

Latest AI and machine learning research in hepatitis for healthcare professionals.

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Reverse engineering protection: A comprehensive survey of reverse vaccinology-based vaccines targeting viral pathogens.

Vaccines have significantly reduced the impact of numerous deadly viral infections. However, there is an increasing need to expedite vaccine development in light of the recurrent pandemics and epidemics. Also, identifying vaccines against certain viruses is challenging due to various factors, notably the inability to culture certain viruses in cell cultures and the wide-ranging diversity of MHC pr...

Mar 23 2024 38523003

Construction of an aerolysin-based multi-epitope vaccine against an machine learning and artificial intelligence-supported approach.

, a gram-negative coccobacillus bacterium, can cause various infections in humans, including septic arthritis, diarrhea (traveler's diarrhea), gastroenteritis, skin and wound infections, meningitis, fulminating septicemia, enterocolitis, peritonitis, and endocarditis. It frequently occurs in aquatic environments and readily contacts humans, leading to high infection rates. This bacterium has exhib...

Mar 1 2024 38495891
Immunization against inhibin DNA vaccine as an alternative therapeutic for improving follicle development and reproductive performance in beef cattle.

The objective of the present study was to investigate the potential role of immunization against INH on follicular development, serum reproductive hor...

Feb 15 2024 38449672
Artificial intelligence compared with human-derived patient educational materials on cirrhosis.

BACKGROUND: The study compared the readability, grade level, understandability, actionability, and accuracy of standard patient educational material a...

Feb 14 2024 38358382
Replication and Injury Associated With SARS-CoV-2 in Cultured Hepatocytes.

BACKGROUND: Liver dysfunction is one of the hallmarks of SARS-CoV-2 infection. The mechanism(s) of hepatic injury in SARS-CoV-2 infection remains cont...

Feb 12 2024 38361525
Donor hepatitis C status is not associated with an increased risk of acute rejection in kidney transplantation.

INTRODUCTION: In renal transplantation, donor hepatitis C virus (HCV) status is crucial to consider when selecting a recipient given the high likeliho...

Feb 6 2024 39845340
Mapping Extracellular Space Features of Viral Encephalitis to Evaluate the Proficiency of Anti-Viral Drugs.

The extracellular space (ECS) is an important barrier against viral attack on brain cells, and dynamic changes in ECS microstructure characteristics a...

Jan 29 2024 38243660
Novel graph-based machine-learning technique for viral infectious diseases: application to influenza and hepatitis diseases.

BACKGROUND: Most infectious diseases are caused by viruses, fungi, bacteria and parasites. Their ability to easily infect humans and trigger large-sca...

Jan 19 2024 38242107
Scoping Review of Deep Learning Techniques for Diagnosis, Drug Discovery, and Vaccine Development in Leishmaniasis.

, a single-cell parasite prevalent in tropical and subtropical regions worldwide, can cause varying degrees of leishmaniasis, ranging from self-limiti...

Jan 17 2024 40303156
Generative artificial intelligence can have a role in combating vaccine hesitancy.

Artificial intelligence has potential to counter vaccine hesitancy while building trust in vaccines, but it must be deployed ethically and responsibly...

Jan 16 2024 38228351
Comparison of hepatitis B and SARS-CoV2 vaccination rates in people who attended Drugs and Addiction Centres.

BACKGROUND AND AIMS: Persons with substance use disorder are at increased risk for hepatitis B virus (HBV) infection. Although most of them are attach...

Jan 16 2024 38292385
Clinical cure induced by pegylated interferon α-2b in the advantaged population of chronic hepatitis B virus infection: a retrospective cohort study.

BACKGROUND: Among the advantaged population with clinical cure of chronic hepatitis B, chronic inactive hepatitis B virus carriers (IHCs) and nucleosi...

Jan 16 2024 38292859
Production of natural flavor compounds using fermented soybean meal extract and their biological potential: a comprehensive study.

This study aims to investigate the production of natural flavor compounds through the utilization of -fermented soybean meal extract and evaluate thei...

Jan 16 2024 38299181
Antifungal activity of the repurposed drug disulfiram against .

Fungal infections have become clinically challenging owing to the emergence of drug resistance in invasive fungi and the rapid increase in the number ...

Jan 11 2024 38273827
CanVaxKB: a web-based cancer vaccine knowledgebase.

Cancer vaccines have been increasingly studied and developed to prevent or treat various types of cancers. To systematically survey and analyze differ...

Jan 9 2024 38204924
A facile approach to preparing personalized cancer vaccines using iron-based metal organic framework.

BACKGROUND: Considering the diversity of tumors, it is of great significance to develop a simple, effective, and low-cost method to prepare personaliz...

Jan 8 2024 38259474
Enhancing voriconazole therapy in liver dysfunction: exploring administration schemes and predictive factors for trough concentration and efficacy.

The application of voriconazole in patients with liver dysfunction lacks pharmacokinetic data. In previous study, we proposed to develop voriconazole...

Jan 4 2024 38239188
Serological and Molecular Characterization of Occult HBV Infection in Blood Donors from South Italy.

Despite good vaccine coverage and careful blood donor selection policies, hepatitis B virus (HBV) is still the most frequent viral infection among blo...

Dec 31 2023 38257771
Prospective Antiviral Effect of Aqueous Extract against COVID-19 Infection.

Marine algal extracts exhibit a potent inhibitory effect against several enveloped and non-enveloped viruses. The infection of severe acute respirator...

Dec 30 2023 38248655
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