Infectious Disease

Hepatitis

Latest AI and machine learning research in hepatitis for healthcare professionals.

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Omics Integration Uncovers Mechanisms Associated with HIV Viral Load and Potential Therapeutic Insights

While antiretroviral therapy (ART) has significantly improved disease prognosis in people with HIV (...

Direct causal variable discovery leveraging the invariance principle: application in biomedical studies

Accurate identification of direct causal (parental) variables for a target is of primary interest in...

Automating Handwritten Vaccination Record Transcription with Generative Multimodal AI Models: A Proof of Concept Study from The Gambia

Handwritten home-based vaccination records (HBRs) are a vital source of immunization data, yet manua...

Predicting Short-Term Mortality in Severe Cirrhosis: An Interpretable Machine Learning Model Integrating Routine Clinical Indicators

The critical need for precise risk stratification in severe liver cirrhosis is underscored by its su...

Human breast cancer is linked to Epstein-Barr virus because it targets stem cells: bioinformatic chromosome correlations

Breast cancer originates from rare “cancer stem cells”. Stem cells are especially susceptible to bec...

Machine Learning-Based Reconstruction of 2D MRI for Quantitative Morphometry in Epilepsy

Structural neuroimaging analyses require ‘research quality’ images, acquired with costly MRI acquisi...

Integration of Gene Expression and Digital Histology to Predict Treatment-Specific Responses in Breast Cancer

Deep learning models applied to digital histology can predict gene expression signatures (GES) and o...

From Sequences to Strategies: Early Detection of New SARS-CoV-2 Variants via Genetic Distance to Reduce Hospitalizations

The COVID-19 pandemic highlighted the critical need for robust methods to monitor viral evolution an...

Candidate Correlates of Protection in the HVTN505 HIV-1 Vaccine Efficacy Trial Identified by Positive-Unlabeled Learning

With a goal of unveiling mechanisms by which vaccines can provide protection against HIV-1 acquisiti...

First-in-Human Study of a First-in-Class AI-Designed Monoclonal Antibody (GB-0669) Against the Conserved SARS-CoV-2 Spike S2 Stem Helix

Antibodies against the SARS-CoV-2 spike receptor-binding domain provided effective COVID-19 treatmen...

Systems Vaccinology Reveals Distinct Immune Signatures of Inhaled and Intramuscular SARS-CoV-2 Vaccination in Humans

Mucosal vaccines may reduce both infection and transmission by engaging local immunity, yet the immu...

Microscale Multiplexed Antigen-Specific Antibody Fc Profiling for Point-of-Care Diagnosis of Tuberculosis

Accurate, affordable tuberculosis (TB) diagnostics that do not require sputum samples are urgently n...

A three-dose MVA-BN mpox vaccination series improves the quality of anti-monkeypox virus immunity

The 2022 global outbreak of clade IIb mpox represented a turning point in public health’s handling o...

Comparison of local large language models for extraction of signs and symptoms data from electronic health records

Electronic health records (EHRs) provide a large source of data that can be used for research purpos...

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