Infectious Disease

Hepatitis

Latest AI and machine learning research in hepatitis for healthcare professionals.

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Using Synthetic Data for Machine Learning-based Childhood Vaccination Prediction in Narok, Kenya

Background: Limited data utilization in low-resource settings poses a barrier to the vaccine delivery ecosystem, undermining efforts to achieve equitable immunization coverage. In nomadic populations, individuals face an increased risk of missing crucial vaccination doses as children. One such population is the Maasai in Narok County, Kenya, where the absence of high-volume, quality data hampers a...

Apr 10 2026 2604.08902v1

ViraHinter: a dual-modal artificial intelligence framework for predicting virus-host interactions

Protein-protein interactions (PPIs) between a virus and its host govern infection, replication, and pathogenesis. While high-throughput mapping has identified thousands of virus-host associations, much of the virus-host interactome remains uncharacterized due to the labor-intensive nature of experimental screens, the inherent difficulty in capturing transient interactions, and the limited sequence...

Apr 3 2026 2604.02842v1
IFN-γ Orchestrates Coordinated Immunosuppression in Head and Neck Squamous Cell Carcinoma Through JAK-STAT-IRF8 Signaling: A Transcriptome-Wide Computational Analysis

Background: Interferon-gamma (IFN-{gamma}) is the primary effector cytokine of adaptive anti-tumor immunity, yet it paradoxically induces a potent imm...

FixationFormer: Direct Utilization of Expert Gaze Trajectories for Chest X-Ray Classification

Expert eye movements provide a rich, passive source of domain knowledge in radiology, offering a powerful cue for integrating diagnostic reasoning int...

Mar 24 2026 2603.22939v1
BAF complexes maintain accessibility at stimulus-responsive chromatin and are required for transcriptional stimulus responses

Background Gene expression changes in response to developmental and environmental cues rely on cis-regulatory sequence elements (cREs). BRG1/BRM-Assoc...

Cov2Pose: Leveraging Spatial Covariance for Direct Manifold-aware 6-DoF Object Pose Estimation

In this paper, we address the problem of 6-DoF object pose estimation from a single RGB image. Indirect methods that typically predict intermediate 2D...

Mar 20 2026 2603.19961v1
HViLM: A Foundation Model for Viral Genomics Enables Multi-Task Prediction of Pathogenicity, Transmissibility, and Host Tropism

Motivation: The emergence of novel viral pathogens poses critical threats to global health, yet current computational approaches for viral risk assess...

Sentiment in Clinical Notes: A Predictor for Length of Stay?

Background: Length of stay (LOS) is a critical metric for hospital operational efficiency. While structured clinical data is widely used to predict LO...

GDPO-SR: Group Direct Preference Optimization for One-Step Generative Image Super-Resolution

Recently, reinforcement learning (RL) has been employed for improving generative image super-resolution (ISR) performance. However, the current effort...

Mar 16 2026 2603.16769v1
Polarized Direct Cross-Attention Message Passing in GNNs for Machinery Fault Diagnosis

The reliability of safety-critical industrial systems hinges on accurate and robust fault diagnosis in rotating machinery. Conventional graph neural n...

Mar 6 2026 2603.06303v1
Deep Learning-based Differentiation of Drug-induced Liver Injury and Autoimmune Hepatitis: A Pathological and Computational Approach

Drug-induced liver injury (DILI) is an acute inflammatory liver disease caused not only by prescription and over-the-counter medications but also by h...

Discovery of a phenazine thiol conjugase from sparse data using genome-informed machine learning

Machine learning has enabled powerful biological discoveries using models trained on large datasets. However, for many important biological questions,...

Predicting how perturbations reshape cellular trajectories with PerturbGen

A major challenge in biology is predicting how cells transition between states over time and how perturbations disrupt these transitions. Understandin...

Direct Contact-Tolerant Motion Planning With Vision Language Models

Navigation in cluttered environments often requires robots to tolerate contact with movable or deformable objects to maintain efficiency. Existing con...

Mar 5 2026 2603.05017v1
An Integrated Computational Antigen Discovery Pipeline with Hierarchical Filtering for Emerging Viral Variants

Emerging and evolving viral diseases, such as SARS-CoV-2, continue to pose significant global health challenges, underscoring the urgent need for rapi...

Improved prediction of virus-human protein-protein interactions by incorporating network topology and viral molecular mimicry

The protein-protein interactions (PPIs) between viruses and human play crucial roles in viral infections. Although numerous computational approaches h...

Direct Reward Fine-Tuning on Poses for Single Image to 3D Human in the Wild

Single-view 3D human reconstruction has achieved remarkable progress through the adoption of multi-view diffusion models, yet the recovered 3D humans ...

Mar 3 2026 2603.02619v1
Leveraging large language models to address common vaccination myths and misconceptions

Large language models (LLMs) are increasingly used by the public to seek health information, yet their reliability in addressing common vaccine myths ...

t2pmhc: A Structure-Informed Graph Neural Network to predict TCR-pMHC Binding

Mapping of T cell receptors (TCRs) to their cognate MHC-presented peptides (pMHC) is central for the development of precision immunotherapies and vacc...

Automated Model Discovery Based on COVID-19 Epidemiologic Data

The COVID-19 pandemic has presented severe challenges in understanding and predicting the spread of infectious diseases, necessitating innovative appr...

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