HIV/AIDS

Improving fold resistance prediction of HIV-1 against protease and reverse transcriptase inhibitors using artificial neural networks.

BACKGROUND: Drug resistance in HIV treatment is still a worldwide problem. Predicting resistance to ...

Stroke: Wearable robot aids walking after stroke.

Identification of non-activated lymphocytes using three-dimensional refractive index tomography and machine learning.

Identification of lymphocyte cell types are crucial for understanding their pathophysiological roles...

Safety, efficacy, and pharmacokinetics of single-tablet elvitegravir, cobicistat, emtricitabine, and tenofovir alafenamide in virologically suppressed, HIV-infected children: a single-arm, open-label trial.

BACKGROUND: No once-daily single-tablet regimen is available for HIV-infected children under 12 year...

Projections as visual aids for classification system design.

Dimensionality reduction is a compelling alternative for high-dimensional data visualization. This m...

Unlocking echocardiogram measurements for heart disease research through natural language processing.

BACKGROUND: In order to investigate the mechanisms of cardiovascular disease in HIV infected and uni...

Magnetic Properties as a Proxy for Predicting Fine-Particle-Bound Heavy Metals in a Support Vector Machine Approach.

The development of a reasonable statistical method of predicting the concentrations of fine-particle...

Cascade recurring deep networks for audible range prediction.

BACKGROUND: Hearing Aids amplify sounds at certain frequencies to help patients, who have hearing lo...

Auditory prediction errors as individual biomarkers of schizophrenia.

Schizophrenia is a complex psychiatric disorder, typically diagnosed through symptomatic evidence co...

Disseminated cutaneous histoplasmosis with laryngeal involvement in a setting of immune reconstitution inflammatory syndrome.

INTRODUCTION: Histoplasmosis is a systemic mycosis caused by the dimorphic fungus . We report a case...

Constrained binary classification using ensemble learning: an application to cost-efficient targeted PrEP strategies.

Binary classification problems are ubiquitous in health and social sciences. In many cases, one wish...

Sensitive detection of rare disease-associated cell subsets via representation learning.

Rare cell populations play a pivotal role in the initiation and progression of diseases such as canc...

Delays in switching patients onto second-line antiretroviral treatment at a public hospital in eThekwini, KwaZulu-Natal.

BACKGROUND: South Africa has one of the largest antiretroviral treatment (ART) programmes globally. ...

Study of Structure-active Relationship for Inhibitors of HIV-1 Integrase LEDGF/p75 Interaction by Machine Learning Methods.

HIV-1 integrase (IN) is a promising target for anti-AIDS therapy, and LEDGF/p75 is proved to enhance...

The Design, Prototyping, and Formative Evaluation of an Assistive Robotic Table (ART) for Stroke Patients.

OBJECTIVE: This article presents the results of an exploratory study in which 14 healthcare subject ...

Evolving Network Model That Almost Regenerates Epileptic Data.

In many realistic networks, the edges representing the interactions between nodes are time varying. ...

A stability-indicating LC-MS/MS method for zidovudine: Identification, characterization and toxicity prediction of two major acid degradation products.

Zidvovudine (AZT) is a nucleoside analogue reverse transcriptase inhibitor (NRTI), a class of anti-r...

Retinal Microvasculopathy Is Common in HIV/AIDS Patients: A Cross-Sectional Study at the Cape Coast Teaching Hospital, Ghana.

. The purpose of this study was to evaluate the ocular disorders in HIV positive patients attending ...

Role of LCAT and Apo A-I in Newly Diagnosed HIV Patients.

Human immunodeficiency virus (HIV) infection is a growing concern for health workers. The two major ...

Prediction of HIV-1 protease cleavage site using a combination of sequence, structural, and physicochemical features.

BACKGROUND: The human immunodeficiency virus type 1 (HIV-1) aspartic protease is an important enzyme...

CD4 T Helper Cells Instruct Lymphopenia-Induced Memory-Like CD8 T Cells for Control of Acute LCMV Infection.

Lymphopenic conditions lead to expansion of memory-like T cells (T), which develop from naïve T cell...