Hospital-Based Medicine

Latest AI and machine learning research in hospital-based medicine for healthcare professionals.

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Underperformance of Machine Learning Algorithms Predicting Extended Lengths of Stay and Readmission in Underrepresented Patient Cohorts After Primary Total Hip Arthroplasty.

BACKGROUND: The demand for total hip arthroplasty (THA) is increasing, yet disparities in access and outcomes persist across racial, ethnic, and socioeconomic groups. Machine learning (ML) models can aid in predicting THA complications such as prolonged lengths of stay (LOS) and 30-day readmission, which is particularly useful for populations at risk of poorer outcomes. However, limited studies to...

May 13 2026 42134630

Carbonic anhydrase under the computational lens: a review of advances, challenges, and future directions.

CONTEXT: Carbonic anhydrases (CAs) are zinc metalloenzymes responsible for the catalysis of the reversible hydration of carbon dioxide and play pivotal roles in many physiological and pathological processes. The complexity of CA isoforms with distinct expression patterns and catalytic characteristics has aroused fierce interest in the development of isoform-selective inhibitors and activators for ...

May 13 2026 42126448
Equitable Digital Frailty Screening for Marginalized Older Adults Using Audio Computer-Assisted Self-Interview: Collaborative Development Guide and User Testing Study.

BACKGROUND: Older adults facing social or structural marginalization for reasons such as lower literacy, digital exclusion, financial constraints, res...

May 13 2026 42126946
Hemovigilance in a Brazilian Amazon blood center: A temporal analysis of 5-year consumption patterns.

BACKGROUND: The transfusion of blood components remains a cornerstone in the management of hematological and onco-hematological diseases. Effective bl...

May 13 2026 42127747
Clinically-applicable prediction of hospital stay and patient similarity retrieval in paediatric cardiology using machine learning.

Paediatric cardiology presents challenges due to the rarity and complexity of conditions like congenital heart disease. Using retrospective electronic...

May 13 2026 42129161
Deep-learning time-series anomaly detection of acute kidney injury from creatinine-eGFR trajectories in the ICU.

Acute kidney injury (AKI) is common in the intensive care unit (ICU), and fixed creatinine thresholds may miss clinically relevant dynamics. We tested...

May 13 2026 42127090
Machine learning to predict survival in patients treated for hepatocellular carcinoma: a systematic review.

BACKGROUND: Given the interplay of cirrhosis with malignancy, management of hepatocellular carcinoma (HCC) relies on multidisciplinary clinician judge...

May 12 2026 42155307
Machine learning models for predicting readmission after stroke: A systematic review and meta-analysis.

BACKGROUND: Hospital readmission following stroke poses a significant challenge for healthcare systems. Machine learning (ML) offers the potential to ...

May 12 2026 42134253
Interpretable machine learning for predicting in-hospital mortality in COPD ICU patients: a rigorous validation across time and geography.

BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a common reason for admission to the intensive care unit (ICU), where accurate risk strati...

May 12 2026 42121158
Development and external validation of an interpretable early prediction model for acute kidney injury using TabPFN and routine admission data: a retrospective cohort study.

BACKGROUND: Acute kidney injury (AKI) is a common and serious complication among hospitalized patients, and early risk stratification remains challeng...

May 12 2026 42121180
Benchmarking large language models in breast cancer care: agreement with radiology-led multidisciplinary tumor board decisions.

BACKGROUND: Multidisciplinary tumor boards (MDTBs) play a central role in breast cancer management by integrating imaging findings with clinical and p...

May 12 2026 42121209
Diagnostic stewardship monitoring systems: institutional and system-level approaches.

Diagnostic stewardship-performing the right test for the right patient at the right time-improves diagnostic accuracy and reduces healthcare resource ...

May 12 2026 42116750
Developing a Clinical Prediction Model for Nonimprovement of Depressive Symptoms at Discharge After Treatment of Eating Disorders.

OBJECTIVE: Depressive symptoms are highly prevalent among people with eating disorders (ED). Although at the group level, depressive symptoms tend to ...

May 12 2026 42117565
How robotic platforms have expanded the boundaries of minimally invasive surgery: a narrative review.

Robotic surgery has evolved from a technological adjunct into a major platform for extending the reach of minimally invasive surgery (MIS). In contras...

May 12 2026 42118464
Artificial intelligence for predicting hospital admissions from the emergency department: a prospective, quasi-experimental study.

The use of certain artificial intelligence (AI) tools may improve hospital operational efficiency, in particular in overcrowded emergency departments ...

May 12 2026 42120428
CT-based radiomic markers to predict late-onset seizures after traumatic brain injury.

Post-traumatic epilepsy (PTE) is a major long-term complication of traumatic brain injury (TBI), but early risk prediction remains imprecise. Radiomic...

May 12 2026 42120454
A TyG-UHR-based machine learning model for screening lean MAFLD: development and external validation.

BACKGROUND: Lean metabolic dysfunction-associated fatty liver disease (MAFLD) is increasingly recognized but often goes unnoticed during health checku...

May 11 2026 42116045
Machine Learning Prediction for 6-Month Outcomes in Traumatic Cerebral Venous Sinus Thrombosis.

This study developed and externally validated a multicenter machine learning framework to predict 6-month poor functional outcome (modified Rankin Sca...

May 11 2026 42116686
EJHF expert consensus statement on the diagnosis and management of hypertrophic cardiomyopathy.

Hypertrophic cardiomyopathy (HCM) is the most prevalent genetic cardiac disease and a leading cause of heart failure, arrhythmia, and sudden cardiac d...

May 11 2026 41771101
Integrated imaging-informed and machine learning-based prognostic models for risk stratification in connective tissue disease-associated interstitial lung disease: a multicenter study.

OBJECTIVES: Connective tissue disease-associated interstitial lung disease (CTD-ILD) exhibits heterogeneous clinical outcomes, and traditional ILD-GAP...

May 11 2026 42113391
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