Hospital-Based Medicine

Latest AI and machine learning research in hospital-based medicine for healthcare professionals.

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Interpretable machine learning model for predicting in-hospital mortality in elderly acute pancreatitis: Development and validation in a multicenter cohort.

BACKGROUND: Elderly acute pancreatitis (AP) patients face significantly higher in-hospital all-cause mortality, highlighting the need for effective risk stratification to support timely clinical decision-making. METHODS: We conducted a multicenter retrospective study that enrolled 2,728 elderly AP patients, with which we developed and validated a robust machine learning (ML) model for predicting i...

Jan 18 2026 41570423

Development and validation of an interpretable machine learning model for non-invasive screening of precancerous gastric lesions using symptom and lifestyle data: a multicentre cohort study.

BACKGROUND: Precancerous gastric lesions (PLGC) are a critical stage in gastric cancer progression, where timely intervention can substantially reduce mortality. However, current screening strategies are predominantly endoscopic, which are invasive, costly, and often inaccessible in resource-limited settings. We aimed to develop and validate an interpretable machine learning model for non-invasive...

Jan 17 2026 41623856
A novel hypothetical protein (SAUSA300_1684) confers excellent protection against multi-drug-resistant Staphylococcus aureus infection in the murine model.

Staphylococcus aureus is a leading cause of nosocomial infections, including sepsis, bacteraemia, pneumonia, and endocarditis, and continues to pose a...

Jan 17 2026 41548530
A Study on the Effectiveness of Al-Assisted Patient Health Education Using Voice Cloning and ChatGPT: A Prospective Randomized Controlled Trial.

BACKGROUND: Traditional patient education often lacks personalization and engagement, potentially limiting knowledge acquisition and treatment adheren...

Jan 17 2026 41548948
Rebuilding the pelvis: advances in robotic-assisted management of complex pelvic fractures.

Complex pelvic fractures are infamously challenging to fix surgically because of their fine anatomy and proximity to vital neurovascular structures. T...

Jan 16 2026 41543252
Development of a machine learning model to predict intensive care unit bed demand for adult elective surgical patients at a large United Kingdom National Health Service Trust.

BACKGROUND: Elective surgical admissions form a growing share of demand for ICU beds, a constrained resource. Capacity planning for these admissions i...

Jan 16 2026 41586383
A federated learning framework for ethical dynamic treatment allocation across heterogeneous hospitals.

OBJECTIVE: In this paper, we propose an adaptive federated learning framework to learn optimal treatments for individual hospitals that possibly serve...

Jan 16 2026 41548733
NLP-ROPCare: predicting retinopathy of prematurity with admission notes using natural language processing.

OBJECTIVES: Retinopathy of prematurity (ROP) is a leading cause of blindness in children worldwide, requiring more efficient models to help predict tr...

Jan 16 2026 41545231
Plasma glutamic acid predicts myelosuppression and mortality in septic patients using machine learning.

Myelosuppression is a common secondary manifestation of sepsis and is associated with increased morbidity and mortality. Recent evidence suggests that...

Jan 16 2026 41545523
AI-assisted multimodal assessment for right ventricular function from echocardiography predicts mortality in patients with pulmonary hypertension and right heart failure.

Right ventricular (RV) strain is an important factor in evaluating RV function. This study aimed to predict mortality in patients with pulmonary hyper...

Jan 16 2026 41545551
Lactate to albumin ratio predicts one year mortality in ICU patients receiving invasive mechanical ventilation.

The lactate-to-albumin ratio (LAR), a composite biomarker reflecting both inflammatory burden and nutritional status, has been associated with adverse...

Jan 16 2026 41545666
Survival and Surrogate Biomarkers in Interventional Oncology Trials: Pitfalls, Challenges, and Future Directions.

INTRODUCTION: Interventional oncology (IO) is a key component of multidisciplinary cancer care, delivering minimally invasive therapies with safety an...

Jan 16 2026 41545771
A Deep Learning Model for Dynamic Prediction of Acute Kidney Injury in Heart Failure Patientss.

BACKGROUND: This study aimed to develop and validate a dynamic prediction model for acute kidney injury (AKI) in heart failure (HF) patients. METHODS:...

Jan 16 2026 41548653
Diagnostic Accuracy of the National Library of Medicine (NLM) Screener Application in Screening for Malaria Parasites Among Blood Donors at the Korle-Bu Blood Bank, Ghana: A Cross-Sectional Study.

BACKGROUND AND AIMS: Malaria is a deadly disease spread through the bite of an infected female Anopheles mosquito and remains the leading cause of mor...

Jan 16 2026 41550292
Construction of a classification system for long-term care service needs among the elderly based on cluster analysis and machine learning: A multi-center, cross-sectional study in central China.

BACKGROUND: Rapid global aging has led to an increasing demand for long-term care services for the elderly; however, current long-term care systems ar...

Jan 15 2026 41619455
Prognostic Significance of Computed Tomography Severity Score for Machine Learning Prediction of Intensive Care Unit Admission in COVID-19 Patients.

OBJECTIVE: The computed tomography-severity score (CT-SS) quantifies the severity of pulmonary involvement and is significantly associated with diseas...

Jan 15 2026 41536171
Comparable Outcomes in Pediatric and Adult Patients With Sudden Sensorineural Hearing Loss.

OBJECTIVE: To identify prognostic factors for unilateral idiopathic sudden sensorineural hearing loss (SSNHL) in pediatric and adult patients, and to ...

Jan 15 2026 41537280
[Surgery in the hospital and the practice : Chances, challenges and perspectives in otorhinolaryngology].

Operative ear, nose and throat (ENT) medicine in Germany is facing a profound structural change, which is significantly influenced by the ongoing hosp...

Jan 15 2026 41537842
The balance between artificial and human intelligence in clinical practice.

INTRODUCTION: Artificial intelligence (AI) is becoming increasingly integrated into clinical care in hand surgery. Its applications extend across diag...

Jan 15 2026 41540778
Identification of Risk Factors and Development of Machine Learning Prediction Models for Inpatient Calcium Pyrophosphate Deposition Disease Flares.

OBJECTIVE: The risk factors for inpatient calcium pyrophosphate deposition disease (CPPD) flares remain poorly defined. This study aimed to identify i...

Jan 14 2026 41532324
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