Hypertension

Comparison of Left Ventricular Ejection Fraction Among 18F-FDG Dual-Gated PET/CT, Single-Gated PET/MRI, and Cardiac MRI.

Left ventricular ejection fraction (LVEF) is a critical parameter in the evaluation of cardiac function, and its measurement can guide treatment decisions in patients with breast cancer undergoing chemotherapy. We obtained LVEF measurements with gated PET-based methods to determine if they produced comparable results to those obtained with cardiac MRI. Methods: Patients with breast cancer who visi...

Adiposome Lipidomic Shifts Following Bariatric Surgery in Association With Weight Loss and Cardiometabolic Benefit.

CONTEXT: Adiposomes carry bioactive lipids that shape systemic metabolism and vascular function. OBJECTIVE: Building on our previous findings that obese adiposomes are ceramide/free fatty acid-enriched and linked to dysfunction, we tested whether bariatric surgery remodels adiposome lipidomes and whether these shifts track with metabolic and vascular improvements. METHODS: Twenty-three obese indiv...

Coronary artery disease diagnosis with signal processing and machine learning of heart sound signals: a systematic review.

Coronary artery disease (CAD) remains a major contributor to morbidity and mortality worldwide. Heart sound analysis has been investigated as a noninv...

Deep learning-based identification of chronic pulmonary embolism on CTPA: a regional lung analysis using multiplanar MIP images.

OBJECTIVE: Chronic pulmonary embolism (CPE) and chronic thromboembolic pulmonary hypertension (CTEPH) are challenging to diagnose, with delayed detect...

Bioinspired hybrid optimisation and deep belief neural networks for early chronic kidney disease detection: an explainable clinical AI framework.

The early detection of chronic kidney disease (CKD) can lead to timely and appropriate clinical intervention. However, most CKD diagnostic systems rel...

Protective Effect of the FOXO3 Gene in Cardiometabolic Disease in the CHAMP Cohort.

Recent findings from the Honolulu Heart Program cohort in Hawaii suggest a longevity-associated variant of FOXO3 may provide resilience against cardio...

Clustering of cardiovascular risk factors and their association with socio-demographic and lifestyle factors in middle-aged and older adults in rural northeast South Africa: Findings from HAALSI.

OBJECTIVES: This study examined patterns of clustering of intermediate risk factors for Cardiovascular diseases (CVDs) in a rural South African popula...

Mortality score in chronic coronary syndrome: prediction model from the ISCHEMIA trial.

AIMS: Accurate stratification of mortality risk is essential for management of chronic coronary syndromes (CCS), but existing models focus primarily o...

Enhanced predictive performance of artificial intelligence in individualized ovarian stimulation of in vitro fertilization: a retrospective cohort study.

BACKGROUND: Over 2.5 million cycles in vitro fertilization (IVF) are conducted annually, and numbers are expected to rise with the aging population. T...

Interpretable evaluation of physiological signals for biometric identification.

Biometric systems using physiological signals have shown high identification accuracy (IA) and low Equal Error Rate (EER). However, existing research ...

Automated Classification of Mitral and Tricuspid Regurgitation With Explainability and Real-World Practice Experience.

BACKGROUND: Mitral regurgitation and tricuspid regurgitation frequently coexist and are evaluated using overlapping echocardiographic views. Although ...

Real-Time Peripheral Revascularization Planning in Chronic Limb Threatening Ischemia Using HarVI: A Digital Twin Approach.

BACKGROUND: Peripheral artery disease (PAD) is a leading cause of limb loss and morbidity worldwide, with chronic limb-threatening ischemia (CLTI) rep...

Race/ethnicity, disability, and antenatal depression in the United States: population-level insights from machine learning.

OBJECTIVE: Women with intersecting identities, such as being both Black and disabled, face heightened risk of antenatal depression, yet few studies ex...

Geometry-aware PointNet for rapid prediction of cerebral aneurysm hemodynamics.

BACKGROUND AND OBJECTIVE: Cerebral aneurysms affect 2-5% of the global population and pose a significant health risk upon rupture. While computational...

Modifiable risk factors associated with increased retinal age gap in an Australian population.

Retinal age gap (RAG)-the difference between retina-predicted age and chronological age-indicates biological ageing that has been linked to the risk o...

PAH-former: Transfer learning for efficient discovery of pulmonary arterial hypertension-associated genes.

BACKGROUND AND AIMS: Pulmonary arterial hypertension (PAH) is a severe disease with limited effective therapies, making the discovery of new therapeut...

In vivo quantification of arterial active mechanics using deep learning-assisted pressure-area analysis.

Active arterial mechanics, governed by vascular smooth muscle contraction, are critical to physiological regulation, cardiovascular disease progressio...

Heterogeneous associations of a mobile health-based disease management program on uncontrolled hypertension: A target trial emulation study.

Long-term effectiveness of digital health interventions for hypertension remains unclear, particularly regarding individual variability in treatment r...

Non-contrast multimodal cardiac MRI for predicting coronary microvascular dysfunction in patients with hypertrophic cardiomyopathy.

OBJECTIVE: In hypertrophic cardiomyopathy (HCM), detection of coronary microcirculatory dysfunction (CMD) usually relies on contrast-enhanced cardiac ...

Comparison of Atheroma Burden Changes Using Conventional vs. End-Diastolic Intravascular Ultrasound Segmentation　- Post Hoc Analysis of the PACMAN-AMI Study.

BACKGROUND: This study compared changes in percentage atheroma volume (PAV) using an end-diastolic (ED) intravascular ultrasound (IVUS) segmentation a...