Infection control / Modes of transmission

Extremozymes for food fermentation: Integrating AI, metagenomics, and protein engineering.

Climate change-induced fluctuations in temperature, pH, salinity, and water activity are increasingly compromising microbial metabolism and fermentation efficiency, exposing the limitations of conventional mesophilic enzymes in maintaining process stability and product consistency. Extremozymes, derived from extremophilic microorganisms, exhibit exceptional structural stability and catalytic activ...

The tire antioxidant derivative 6PPD-quinone exacerbates IBD by targeting NR1H4-mediated lipid metabolism and mitochondrial dysfunction in human colon epithelial cells.

N- (1,3-Dimethylbutyl)-N'-phenyl-p-phenylenediamine quinone (6PPD-Q), a tire rubber antioxidant derivative, accumulates in air, soil, and water and has been found in urine, blood, and cerebrospinal fluid, posing significant health risks. Although 6PPD-Q exhibits intestinal toxicity, its role in inflammatory bowel disease (IBD) remains unclear. The objective of this study was to identify key molecu...

Visual steatosis assessment: method-dependent variation and systematically higher estimates compared with AI measurement.

AIMS: Despite its clinical importance, histological steatosis assessment remains poorly standardized and highly variable among pathologists. We examin...

Stress-Induced Electronic/Atomic Interfacial Evolution of MXene/MoS2-Ionic Liquid Heterostructures Enables Adaptive Lubrication in Epoxy Coatings.

The tribological performance of MXene/MoS2 heterostructure-based polymer coatings is limited by an incomplete understanding of electronic/atomic inter...

Remote sensing for monitoring and managing Eichhornia crassipes: a review of methods, applications, and decision-support frameworks.

Eichhornia crassipes (water hyacinth) is among the world's most aggressive aquatic invasive plants, with severe ecological and socioeconomic impacts o...

Global monitoring of methane point sources using deep learning on hyperspectral radiance measurements from EMIT.

Anthropogenic methane (CH4) point sources are critical drivers of near-term climate forcing, safety hazards, and system-inefficiencies. Space-based im...

Spiking neural networks based on a discrete second-order memristive synapse: Modeling, dynamics, and applications.

Discrete-time spiking neural networks provide an important framework for modeling discrete memristive synapses and for investigating their spike trans...

YOTO++: Learning Long-Horizon Closed-Loop Bimanual Manipulation From One-Shot Human Video Demonstrations.

Bimanual robotic manipulation remains a fundamental challenge due to the inherent complexity of dual-arm coordination and high-dimensional action spac...

Can LLMs reliably perform epidemiological extraction in elite football?

Anterior cruciate ligament (ACL) injuries remain a critical burden in professional football, resulting in prolonged absence and high economic costs. W...

Self-Powered Liquid TVNG Sensor for Robot Tactile and Gustatory Dual-Mode Sensing System.

Tribovoltaic nanogenerator (TVNG) offers self-powered, low impedance, and high direct current transient response, making it highly suitable for roboti...

A data-driven approach to hepatitis C forecasting using machine learning and epidemiological models.

The hepatitis C virus is a significant global health concern and a major cause of chronic liver disease. Therefore, developing a mathematical model is...

De Novo Molecular Design and Bioactivity Prediction of Novel Hexahydroquinolines as Plasmodium falciparum Calcium-Dependent Protein Kinase 4 (CDPK4) Inhibitors.

Plasmodium falciparum Calcium-Dependent Protein Kinase 4 (PfCDPK4) is a validated target for malaria transmission-blocking interventions, as its inhib...

Deformation-Adaptive Hybrid Triboelectric-Piezoelectric Nanogenerator for Wearable Muscle Monitoring and Human-Machine Interaction.

Wearable systems for real-time and long-term musculoskeletal monitoring are increasingly required as shoulder-neck disorders and upper-arm injuries be...

Machine Learning Model Development and Evaluation for Non-contact Lower Limb Injury Risk Prediction in Elite Male Rugby Union: A Multi-team, Multi-season Analysis.

BACKGROUND: The prevalence, incidence rate and burden of injuries are high in rugby union. Despite the growing application of machine learning for inj...

Event-triggered impulsive control for switched delay systems and its application in image encryption of switched neural networks.

This paper addresses the event-triggered impulsive control problem for nonlinear switched systems with time delay. The main challenge is that the dela...

[Dual-axis evolution model of physical intervention-bioprinting depth for in situ 3D bioprinting in vivo and research perspectives].

In situ 3D bioprinting in vivo is leading a profound paradigm shift of manufacturing in regenerative medicine. However, to achieve the leap from mere ...

Recent advances in green printing materials and technologies.

Green printing has emerged as a powerful additive manufacturing strategy for fabricating functional materials and devices over large areas, while redu...

Machine Learning of Temperature-Dependent Chemical Kinetics Using Parallel Droplet Microreactors.

Temperature is a fundamental regulator of chemical and biochemical kinetics, yet capturing nonlinear thermal effects directly from experimental data r...

A review of research on crawling soft robots: bionic mechanisms and actuation motion.

Crawling soft robots have attracted widespread attention due to their high adaptability to unstructured environments. However, existing research often...

Toward foundation-model-assisted biomechanical simulation of the knee joint: Current evidence, limitations, and future directions.

Subject-specific finite element analysis (FEA) can estimate tissue-level stress, strain, contact pressure, and load transfer in the knee, but building...