Latest AI and machine learning research in infectious disease for healthcare professionals.
The -1 programmed ribosomal frameshifting (-1 PRF) in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is crucial for keeping the balance between pp1a and pp1ab polyproteins. To date, the host factors influencing this process remain poorly understood. Using RNA pull-down assays combined with mass spectrometry screening, we discovered five host proteins interacting with -1 PRF RNA, incl...
Little is known about host-gut microbiome interactions within natural populations at the intestinal mucosa, the primary interface. We investigate associations between the intestinal microbiome and mucosal immune measures while controlling for host, social and ecological factors in 199 samples of 158 wild spotted hyenas (Crocuta crocuta) in the Serengeti National Park, Tanzania. We profile the micr...
Microbial communities in hot springs are distributed globally and have been extensively characterized regarding their diversity and composition. Howev...
Bacterial infections present a significant threat to human health, and accurate identification of infection type is crucial for both clinical and fore...
OBJECTIVES: To develop and evaluate forecasting models using the Holt-Winters statistical approach and the long short-term memory (LSTM) deep learning...
BACKGROUND: Detecting valve vegetation in infective endocarditis (IE) poses challenges, particularly with mechanical valves, because acoustic shadowin...
Clinical management and surveillance of the complex (ECC) face significant challenges due to inaccurate species identification and prolonged turnarou...
BACKGROUND: Growing evidence links immune dysfunction, notably impaired IFNγ production, to chronic pulmonary aspergillosis (CPA), but understanding o...
Lactylation, a novel post-translational modification, has been implicated in various pathophysiological processes; however, its role in sepsis-associa...
The kidney is a target organ for the dysregulated host response to infection that defines sepsis, and acute kidney injury (AKI) is often an early mani...
The development of therapeutics builds on testing their efficiency in vitro. To optimize gene therapies, for example, fluorescent reporters expressed ...
The perspective review discusses predictive stability computational modeling and scientific risk-based approaches to prospectively assess long-term st...
BACKGROUND: Predicting seasonal and emerging waves of respiratory viruses is crucial for effective public health responses. Despite significant effort...
PURPOSE: Stroke-associated pneumonia (SAP), a critical complication of ischemic stroke, significantly worsens outcomes. Our aim was to identify SAP ri...
Availability of ultraportable chest x-ray (CXR) and advancements in artificial intelligence (AI)-enabled CXR interpretation are promising developments...
Cervical cancer remains a leading cause of cancer-related death among women globally, despite the availability of effective prevention through human p...
Developing vaccines with a better stability is an area of improvement to meet the global health needs of preventing infectious diseases. With the adva...
BACKGROUND OBJECTIVES: Malaria is a global health issue, causing over two million deaths annually. The development of new and potent antimalarial drug...
Microscopy and image analysis play a vital role in parasitology research; they are critical for identifying parasitic organisms and elucidating their ...
Accumulating evidence indicates that microorganisms respond to the ubiquitous plastic pollution by evolving plastic-degrading enzymes. However, the fu...