Infectious Disease

Latest AI and machine learning research in infectious disease for healthcare professionals.

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In silico evolution of autoinhibitory domains for a PD-L1 antagonist using deep learning models.

There has been considerable progress in the development of computational methods for designing protein-protein interactions, but engineering high-affinity binders without extensive screening and maturation remains challenging. Here, we test a protein design pipeline that uses iterative rounds of deep learning (DL)-based structure prediction (AlphaFold2) and sequence optimization (ProteinMPNN) to d...

Nov 30 2023 38032933

A bibliometric analysis on discovering anti-quorum sensing agents against clinically relevant pathogens: current status, development, and future directions.

BACKGROUND: Quorum sensing is bacteria's ability to communicate and regulate their behavior based on population density. Anti-quorum sensing agents (anti-QSA) is promising strategy to treat resistant infections, as well as reduce selective pressure that leads to antibiotic resistance of clinically relevant pathogens. This study analyzes the output, hotspots, and trends of research in the field of ...

Nov 30 2023 38098670
Evaluation of sensory acceptance, purchase intention and color parameters of potentially probiotic mead with .

Mead is a fermented alcoholic beverage produced by yeast action on a diluted solution of honey. In this study, for the first time, sensory acceptance,...

Nov 29 2023 38623422
Optimizing artificial intelligence in sepsis management: Opportunities in the present and looking closely to the future.

Sepsis remains a major challenge internationally for healthcare systems. Its incidence is rising due to poor public awareness and delays in its recogn...

Nov 29 2023 38263963
Carvacrol Treatment Reduces Decay and Maintains the Postharvest Quality of Red Grape Fruits ( L.) Inoculated with .

In this study, we isolated and identified pathogenic fungi from the naturally occurring fruits of red grapes, studied their biological characteristics...

Nov 29 2023 38231758
Antiproliferative Cancer Cell and Fungicidal Effects of Yellow and Red Araçá ( Sabine) Fruit Extract.

Araçá is a native Brazil fruit, and has two morphological types, yellow and red; however, it is still little consumed by the population. Although ther...

Nov 29 2023 38231761
Increase in Lactulose Content in a Hot-Alkaline-Based System through Fermentation with a Selected Lactic Acid Bacteria Strain Followed by the β-Galactosidase Catalysis Process.

In this study, lactic acid bacteria (LAB) fermentation and β-galactosidase catalysis methods were combined to increase the lactulose concentration and...

Nov 29 2023 38231767
Effective Preventative Measures are Essential to Lower Disease Burden From Dengue and COVID-19 Co-infection in Bangladesh.

Bangladesh is widely recognized as one of the dengue prone nations, and empirical evidence has consistently demonstrated an upward trend in the severi...

Nov 29 2023 38035255
Antibiofilm Effects of Oleuropein against : An In Vitro Study.

has posed a huge threat to human health and the economy. Oleuropein has antibacterial activities against various microorganisms but research on its e...

Nov 28 2023 38231779
The application of artificial intelligence in the management of sepsis.

Sepsis is a complex and heterogeneous syndrome that remains a serious challenge to healthcare worldwide. Patients afflicted by severe sepsis or septic...

Nov 28 2023 38283255
Improving the microbial and physicochemical shelf life of yufka paste using and calcium propionate.

Considering the importance of reducing the use of chemical preservatives in food and the increasing attention of consumers to consume food products wi...

Nov 27 2023 38455183
Antibacterial and Antiviral Properties of Essential Oil.

The Korean mountains are home to the Korean red pine (). Pine needle oil has been used as a food additive and a traditional herbal medicine; however, ...

Nov 27 2023 38231728
Distinguishing infectivity in patients with pulmonary tuberculosis using deep learning.

INTRODUCTION: This study aimed to develop and assess a deep-learning model based on CT images for distinguishing infectivity in patients with pulmonar...

Nov 27 2023 38089031
FIAMol-AB: A feature fusion and attention-based deep learning method for enhanced antibiotic discovery.

Antibiotic resistance continues to be a growing concern for global health, accentuating the need for novel antibiotic discoveries. Traditional methodo...

Nov 25 2023 38056212
Enhanced Antibacterial Efficiency and Anti-Hygroscopicity of Gum Arabic-ε-Polylysine Electrostatic Complexes: Effects of Thermal Induction.

The aim of this investigation was to scrutinize the effects of a thermal treatment on the electrostatic complex formed between gum arabic (GA) and ε-p...

Nov 24 2023 38231920
: a novel automated system for malaria diagnosis by using artificial intelligence tools and a universal low-cost robotized microscope.

INTRODUCTION: Malaria is one of the most prevalent infectious diseases in sub-Saharan Africa, with 247 million cases reported worldwide in 2021 accord...

Nov 24 2023 38075929
Study on brain damage patterns of COVID-19 patients based on EEG signals.

OBJECTIVE: The coronavirus disease 2019 (COVID-19) is an acute respiratory infectious disease caused by the SARA-CoV-2, characterized by high infectiv...

Nov 24 2023 38077190
Decoding acute myocarditis in patients with COVID-19: Early detection through machine learning and hematological indices.

During the persistent COVID-19 pandemic, the swift progression of acute myocarditis has emerged as a profound concern due to its augmented mortality, ...

Nov 23 2023 38303719
Association of Intermediate-Stage Age-Related Macular Degeneration with Plasma Inflammatory Biomarkers in Persons with AIDS.

PURPOSE: To evaluate associations of plasma levels of inflammatory biomarkers with age-related macular degeneration (AMD) and cataract in persons with...

Nov 23 2023 38304607
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