Infectious Disease

Latest AI and machine learning research in infectious disease for healthcare professionals.

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Covalent Functionalization of Graphene Sheets with Different Moieties and Their Effects on Biological Activities.

The ongoing spread of multi-drug-resistant bacteria over the past few decades necessitates collateral efforts to develop new classes of antibacterial agents with different mechanisms of action. The utilization of graphene nanosheets has recently gained attention with this respect. Herein, we have synthesized and tested the antibacterial activity of an array of graphene materials covalently functio...

Dec 20 2019 33463246

iQSP: A Sequence-Based Tool for the Prediction and Analysis of Quorum Sensing Peptides via Chou's 5-Steps Rule and Informative Physicochemical Properties.

Understanding of quorum-sensing peptides (QSPs) in their functional mechanism plays an essential role in finding new opportunities to combat bacterial infections by designing drugs. With the avalanche of the newly available peptide sequences in the post-genomic age, it is highly desirable to develop a computational model for efficient, rapid and high-throughput QSP identification purely based on t...

Dec 20 2019 31861928
An antifouling peptide-based biosensor for determination of Streptococcus pneumonia markers in human serum.

We report a peptide-based sensor that involves a multivalent interaction with L-ascorbate 6-phosphate lactonase (UlaG), a protein marker of Streptococ...

Dec 19 2019 31999579
Bioactive-guided structural optimization of 1,2,3-triazole phenylhydrazones as potential fungicides against Fusarium graminearum.

The phytopathogenic fungus Fusarium graminearum is the major causal agent of fusarium head blight (FHB), which is one of the most serious diseases in ...

Dec 19 2019 32284133
Antimicrobial activities of against selected pathogenic fungi and bacteria strains.

and are dangerous pathogens causing fungal diseases. and developed resistance to fungicides such as fluconazole. Similarly, pathogenic bacteria h...

Dec 19 2019 32128281
Annual Report on surveillance for avian influenza in poultry and wild birds in Member States of the European Union in 2018.

Avian influenza (AI) is a viral infectious disease that affects all species of domestic and wild birds. The viruses causing this disease can be of hig...

Dec 19 2019 32626213
Detecting antimicrobial peptides by exploring the mutual information of their sequences.

The rise of antibiotic resistance in pathogenic bacteria is a growing concern for every part of the world. The present study shows the prediction effi...

Dec 18 2019 31760879
Plasma mEV levels in Ghanain malaria patients with low parasitaemia are higher than those of healthy controls, raising the potential for parasite markers in mEVs as diagnostic targets.

This study sought to measure medium-sized extracellular vesicles (mEVs) in plasma, when patients have low early in infection. We aimed to define the ...

Dec 18 2019 32002165
Right Dose Right Now: bedside data-driven personalized antibiotic dosing in severe sepsis and septic shock - rationale and design of a multicenter randomized controlled superiority trial.

BACKGROUND: Antibiotic exposure is often inadequate in critically ill patients with severe sepsis or septic shock and this is associated with worse ou...

Dec 18 2019 31852491
Survey on deep learning for pulmonary medical imaging.

As a promising method in artificial intelligence, deep learning has been proven successful in several domains ranging from acoustics and images to nat...

Dec 16 2019 31840200
Thermosonication parameter effects on physicochemical changes, microbial and enzymatic inactivation of fruit smoothie.

With the aim of developing a fruit-based beverage in products which are severely damaged by heat, a high-intensity ultrasound treatment combined with ...

Dec 16 2019 32327779
In vitro selection of DNA aptamers and their integration in a competitive voltammetric biosensor for azlocillin determination in waste water.

The uncontrolled usage of veterinary antibiotics has led to their widespread pollution in waterways and milk products. Potential impact of antibiotic ...

Dec 16 2019 32029106
Ceftolozane-tazobactam in an elastomeric infusion device for ambulatory care: an in vitro stability study.

OBJECTIVES: Published in vitro stability data for ceftolozane-tazobactam supports intermittent short duration infusions. This method of delivery is no...

Dec 16 2019 32296512
Self-Assembled Polyurethane Capsules with Selective Antimicrobial Activity against Gram-Negative .

This article reports the antimicrobial activity of two segmented amphiphilic polyurethanes, PU-1 and PU-2, containing a primary or secondary amine gro...

Dec 16 2019 33463225
Identification of Tomato Disease Types and Detection of Infected Areas Based on Deep Convolutional Neural Networks and Object Detection Techniques.

This study develops tomato disease detection methods based on deep convolutional neural networks and object detection models. Two different models, Fa...

Dec 16 2019 31933623
Effect of experimental infectious bursal disease virus on clinical signs and pathogenesis of avian influenza virus HN in turkey by real time PCR.

Infectious bursal disease virus (IBDV) in turkeys may result in immunosuppression, and inability of turkeys to resist nonpathogenic or less pathogenic...

Dec 15 2019 32206224
Antioxidant capacity, antimicrobial activities and chemical composition of subsp essential oil.

This study aimed to evaluate the composition, antioxidant capacity and antibacterial effects of subsp. (baneh) essential oil on some important bacte...

Dec 15 2019 32206225
Characterisation and antifungal activity of extracellular chitinase from a biocontrol fungus, PQ34.

species were known as biological control agents against phytopathogenic fungi because they produce a variety of chitinases. Chitinases are hydrolytic...

Dec 14 2019 32128280
Synthesis and in vitro activity of asymmetric indole-based bisamidine compounds against Gram-positive and Gram-negative pathogens.

A series of new asymmetric bisamidine was designed, synthesized, and tested for their in-vitro antibacterial activity using a range of Gram-positive a...

Dec 13 2019 32070637
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