Infectious Disease

Antibiofilm activity of the essential oil of citronella () and its major component, geraniol, on the bacterial biofilms of .

Medicinal plants with antimicrobial action have been investigated for uses against biofilms, among which, , citronella, stands out as a promising species. The present study aims to evaluate the antimicrobial and antibiofilm action of the essential oil of (EOCN) and geraniol on Gram-negative and positive bacteria from the determination of minimum inhibitory concentration (MIC) and minimum bacteric...

Gene Essentiality Analyzed by Transposon Mutagenesis and Machine Learning in a Stable Haploid Isolate of .

Knowing the full set of essential genes for a given organism provides important information about ways to promote, and to limit, its growth and survival. For many non-model organisms, the lack of a stable haploid state and low transformation efficiencies impede the use of conventional approaches to generate a genome-wide comprehensive set of mutant strains and the identification of the genes essen...

Antibacterial efficacy of handrubbing for 15 versus 30 seconds: EN 1500-based randomized experimental study with different loads of Staphylococcus aureus and Escherichia coli.

OBJECTIVES: Compliance with the World Health Organization 'how to handrub' action is suboptimal. Simplifying the hand-hygiene action may improve pract...

Identification of bacteria in juice/lettuce using magnetic nanoparticles and selected reaction monitoring mass spectrometry.

Ensuring food safety requires a rapid and reliable method for detecting food-borne pathogens. Mass spectrometry has been demonstrated as a powerful to...

Pathogen Identification Direct From Polymicrobial Specimens Using Membrane Glycolipids.

With the increased prevalence of multidrug-resistant Gram-negative bacteria, the use of colistin and other last-line antimicrobials is being revisited...

Orthotopic Liver Transplantation After Stereotactic Body Radiotherapy for Pediatric Hepatocellular Carcinoma with Central Biliary Obstruction and Nodal Involvement.

Here we describe the case of a 10-year-old boy with a history of chronic hepatitis B who was diagnosed with hepatocellular carcinoma (HCC) with a larg...

Mexican oregano () essential oil-in-water emulsions: impact of emulsifier type on the antifungal activity of .

This study examined the impact of emulsifier type on the physicochemical characteristics and antifungal capacity of oregano oil-in-water emulsions: Tw...

Increased risk of group B Streptococcus causing meningitis in infants with mannose-binding lectin deficiency.

OBJECTIVES: To evaluate the association of mannose-binding lectin (MBL) deficiency with susceptibility and clinical features of group B Streptococcus ...

Design, synthesis, and biological evaluation of novel benzimidazole tethered allylidenehydrazinylmethylthiazole derivatives as potent inhibitors of .

Tuberculosis (TB) has become one of the most significant public health problems in recent years. Antibiotic therapy remains the mainstay of TB control...

Prediction and functional analysis of prokaryote lysine acetylation site by incorporating six types of features into Chou's general PseAAC.

Lysine acetylation is one of the most important types of protein post-translational modifications (PTM) that are widely involved in cellular regulator...

Analysis of tuberculosis disease through Raman spectroscopy and machine learning.

We present the effectiveness of Raman spectroscopy (RS) in combination with machine learning for screening and analysis of blood sera collected from t...

The Artificial Intelligence Clinician learns optimal treatment strategies for sepsis in intensive care.

Sepsis is the third leading cause of death worldwide and the main cause of mortality in hospitals, but the best treatment strategy remains uncertain. ...

Comparative Evaluation of the Antibacterial Efficacy of Aloe Vera, 3% Sodium Hypochlorite, and 2% Chlorhexidine Gluconate Against Enterococcus faecalis: An In Vitro Study.

Aim To compare the antibacterial efficacy of irrigants (aloe vera, 3% sodium hypochlorite (NaOCl), 2% chlorhexidine (CHX), and saline) against Enteroc...

A multi-strain probiotic administered via drinking water enhances feed conversion efficiency and meat quality traits in indigenous chickens.

Whereas the use of probiotics is commonplace in commercial production of improved chicken strains, little is known about the impact of these live micr...

Machine learning and structural analysis of Mycobacterium tuberculosis pan-genome identifies genetic signatures of antibiotic resistance.

Mycobacterium tuberculosis is a serious human pathogen threat exhibiting complex evolution of antimicrobial resistance (AMR). Accordingly, the many pu...

[Hepatitis B and renal failure: prevalence and associated factors in National University Hospital Center of Cotonou].

INTRODUCTION: the association between the kidneys and hepatitis B is complex. This study aims to determine the prevalence and factors associated with ...

A predictive model for high/low risk group according to oncotype DX recurrence score using machine learning.

BACKGROUND: Oncotype DX(ODX) is a 21-gene breast cancer recurrence score(RS) assay that aids in decision-making for chemotherapy in early-stage hormon...

Deep-RBPPred: Predicting RNA binding proteins in the proteome scale based on deep learning.

RNA binding protein (RBP) plays an important role in cellular processes. Identifying RBPs by computation and experiment are both essential. Recently, ...

Prediction of bioavailability and toxicity of complex chemical mixtures through machine learning models.

Empirical data from a 6-month mesocosms experiment were used to assess the ability and performance of two machine learning (ML) models, including arti...

New bacitracin-resistant nisin-producing strain of and its physiological characterization.

Nisin A belonging to the class I bacteriocins and produced by subsp. is widely used in many countries as highly efficient and safe preservative prev...