Infectious Disease

Latest AI and machine learning research in infectious disease for healthcare professionals.

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An exploratory deep learning approach to investigate tuberculosis pathogenesis in nonhuman primate model: Combining automated radiological analysis with clinical and biomarkers data.

BACKGROUND: Tuberculosis (TB) kills approximately 1.6 million people yearly despite the fact anti-TB drugs are generally curative. Therefore, TB-case detection and monitoring of therapy, need a comprehensive approach. Automated radiological analysis, combined with clinical, microbiological, and immunological data, by machine learning (ML), can help achieve it.

Aug 1 2024 38949157

De novo synthetic antimicrobial peptide design with a recurrent neural network.

Antibiotic resistance is recognized as an imminent and growing global health threat. New antimicrobial drugs are urgently needed due to the decreasing effectiveness of conventional small-molecule antibiotics. Antimicrobial peptides (AMPs), a class of host defense peptides, are emerging as promising candidates to address this need. The potential sequence space of amino acids is combinatorially vast...

Aug 1 2024 38988311
Faculty Perspectives on the Potential of RAG in Computer Science Higher Education

The emergence of Large Language Models (LLMs) has significantly impacted the field of Natural Language Processing and has transformed conversational...

Flusion: Integrating multiple data sources for accurate influenza predictions

Over the last ten years, the US Centers for Disease Control and Prevention (CDC) has organized an annual influenza forecasting challenge with the mo...

Machine learning-assisted substrate binding pocket engineering based on structural information.

Engineering enzyme-substrate binding pockets is the most efficient approach for modifying catalytic activity, but is limited if the substrate binding ...

Jul 25 2024 39101501
DeePhafier: a phage lifestyle classifier using a multilayer self-attention neural network combining protein information.

Bacteriophages are the viruses that infect bacterial cells. They are the most diverse biological entities on earth and play important roles in microbi...

Jul 25 2024 39110476
BioM2: biologically informed multi-stage machine learning for phenotype prediction using omics data.

Navigating the complex landscape of high-dimensional omics data with machine learning models presents a significant challenge. The integration of biol...

Jul 25 2024 39126426
HTINet2: herb-target prediction via knowledge graph embedding and residual-like graph neural network.

Target identification is one of the crucial tasks in drug research and development, as it aids in uncovering the action mechanism of herbs/drugs and d...

Jul 25 2024 39175133
AI-based IsAb2.0 for antibody design.

Therapeutic antibody design has garnered widespread attention, highlighting its interdisciplinary importance. Advancements in technology emphasize the...

Jul 25 2024 39285513
SepsisLab: Early Sepsis Prediction with Uncertainty Quantification and Active Sensing

Sepsis is the leading cause of in-hospital mortality in the USA. Early sepsis onset prediction and diagnosis could significantly improve the surviva...

Development of an Intelligent Health Education System Based on Large Language Model for Elderly Pulmonary Aspiration Prevention.

As the aging process accelerates, the incidence of chronic diseases in the elderly is rising. As a result, it is crucial to optimize health education ...

Jul 24 2024 39049258
Precision Nutrition Management in Continuous Care: Leveraging AI for User-Reported Dietary Data Analysis.

A As health technology advances, this study aims to develop an innovative nutritional intake management system that integrates artificial intelligence...

Jul 24 2024 39049264
PhenoFlow: A Human-LLM Driven Visual Analytics System for Exploring Large and Complex Stroke Datasets

Acute stroke demands prompt diagnosis and treatment to achieve optimal patient outcomes. However, the intricate and irregular nature of clinical dat...

Mapping Patient Trajectories: Understanding and Visualizing Sepsis Prognostic Pathways from Patients Clinical Narratives

In recent years, healthcare professionals are increasingly emphasizing on personalized and evidence-based patient care through the exploration of pr...

Diff4VS: HIV-inhibiting Molecules Generation with Classifier Guidance Diffusion for Virtual Screening

The AIDS epidemic has killed 40 million people and caused serious global problems. The identification of new HIV-inhibiting molecules is of great im...

Identification and validation of potential genes for the diagnosis of sepsis by bioinformatics and 2-sample Mendelian randomization study.

This integrated study combines bioinformatics, machine learning, and Mendelian randomization (MR) to discover and validate molecular biomarkers for se...

Jul 19 2024 39029061
SecureVAX: A Blockchain-Enabled Secure Vaccine Passport System

A vaccine passport serves as documentary proof, providing passport holders with greater freedom while roaming around during pandemics. It confirms v...

Virtual Gram staining of label-free bacteria using darkfield microscopy and deep learning

Gram staining has been one of the most frequently used staining protocols in microbiology for over a century, utilized across various fields, includ...

Discovery of novel antimicrobial peptides with notable antibacterial potency by a LLM-based foundation model

Large language models (LLMs) have shown remarkable advancements in chemistry and biomedical research, acting as versatile foundation models for vari...

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