Obstetrics & Gynecology

Infertility

Latest AI and machine learning research in infertility for healthcare professionals.

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Steroid Metabolome Profiling Identifies a Unique Androgen Hormone Signature Associated with Endometriosis

Endometriosis is a chronic, hormone-dependent condition that affects 190 million women worldwide. There are no validated biomarkers for endometriosis and this delays diagnosis and treatment. We performed serum steroid metabolome profiling in healthy controls (n=57) and women with laparoscopically-confirmed endometriosis (n=159) using liquid chromatography-tandem mass spectrometry. Women with endom...

Regulatory risk loci link disrupted androgen response to pathophysiology of Polycystic Ovary Syndrome

A major challenge in deciphering the complex genetic landscape of Polycystic Ovary Syndrome (PCOS) lies in the limited understanding of how susceptibility loci drive molecular mechanisms across diverse phenotypes. To address this, we integrated molecular and epigenomic annotations from proposed causal cell-types and employed a deep learning (DL) framework to predict cell-type-specific regulatory e...

CausalDRIFT: Causal Dimensionality Reduction via Inference of Feature Treatments for Robust Healthcare Machine Learning

High-dimensional medical datasets present challenges in feature selection, where traditional methods often prioritize spurious correlations over causa...

A Data-Driven Approach to Polycystic Ovary Syndrome Diagnosis: Evaluating Machine Learning Models

PCOS is recognized as a major health concern affecting women around the world. Early detection and treatment of PCOS significantly reduce implications...

Translation of miRNA blood-based discovery to molecular testing for clinical diagnosis of endometriosis

Endometriosis is a common yet often underdiagnosed condition, partly due to the lack of reliable diagnostics. This study examines the clinical feasibi...

Evaluating Conversational Image Segmentation for Medicine: Performance, Failure Modes, and a Fairness Audit Across Seven Modalities

Medical-image segmentation underpins quantitative diagnostics and research, yet state-of-the-art models remain task-specific and data-hungry. The rece...

A Drug Repurposing Strategy for a New Cause of Endometrial Infertility: Unveiling Promising New Treatments

Which mechanisms of action and candidate drugs can be used to treat endometrial failure caused by molecular alterations rather than endometrial timing...

Predicting Polycystic Ovary Syndrome among Reproductive-Aged Women in Bangladesh Using Machine Learning Algorithms: Development of a Hospital-Based Predictive Model

Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders among reproductive aged women, which is characterized by hormonal imbal...

Transcriptome profiling to identify blood biomarkers for peritoneal endometriosis

Peritoneal endometriosis (PE) remains challenging to diagnose, as it cannot be detected using standard imaging modalities and no clinically validated ...

Identification and validation of immune-related and inflammation-related genes in endometriosis.

AIM: Endometriosis is characterized by immune evasion and progressive inflammation. This study aimed to identify key genes related to immune and infla...

Jan 1 2025 40405976
The 'golden fleece of embryology' eludes us once again: a recent RCT using artificial intelligence reveals again that blastocyst morphology remains the standard to beat.

Grading of blastocyst morphology is used routinely for embryo selection with good outcomes. A lot of effort has been placed in IVF to search for the p...

Jan 1 2025 39602554
Using machine learning to predict patients with polycystic ovary disease in Chinese women.

OBJECTIVE: With an estimated global frequency ranging from5 % to 21 %, polycystic ovary syndrome (PCOS) is one of the most prevalent hormonal disorder...

Jan 1 2025 39794054
Current and Future Applications of Artificial Intelligence to Diagnose and Treat Male Infertility.

Artificial intelligence (AI) models are being increasingly applied to modern medicine. Within the field of urology, reproductive urology specifically ...

Jan 1 2025 40301250
Leveraging AI for Automatic Classification of PCOS Using Ultrasound Imaging

The AUTO-PCOS Classification Challenge seeks to advance the diagnostic capabilities of artificial intelligence (AI) in identifying Polycystic Ovary ...

An Integrated Optimization and Deep Learning Pipeline for Predicting Live Birth Success in IVF Using Feature Optimization and Transformer-Based Models

In vitro fertilization (IVF) is a widely utilized assisted reproductive technology, yet predicting its success remains challenging due to the multif...

A Review on the Integration of Artificial Intelligence and Medical Imaging in IVF Ovarian Stimulation

Artificial intelligence (AI) has emerged as a powerful tool to enhance decision-making and optimize treatment protocols in in vitro fertilization (I...

Leveraging artificial intelligence for advancements in reproductive health.

We are writing to address the growing interest in the role of artificial intelligence (AI) within healthcare, particularly in the field of reproductiv...

Nov 30 2024 39757989
[Application of Artificial Intelligence in Sperm Quality Analysis and Sperm Screening].

Infertility is a global health issue, and more and more people are hoping to have babies by means of assisted reproductive technology. However, there ...

Sep 20 2024 39507988
BodySLAM: A Generalized Monocular Visual SLAM Framework for Surgical Applications

Endoscopic surgery relies on two-dimensional views, posing challenges for surgeons in depth perception and instrument manipulation. While Monocular ...

Automated Extraction of Patient-Centered Outcomes After Breast Cancer Treatment: An Open-Source Large Language Model-Based Toolkit.

PURPOSE: Patient-centered outcomes (PCOs) are pivotal in cancer treatment, as they directly reflect patients' quality of life. Although multiple studi...

Aug 1 2024 39167746
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