Inflammatory Bowel Disease

Quantitative whole-body measurement of inflammothrombotic immunologic response disease using Fleming method for tissue and vascular differentiation and metabolism.

BACKGROUND: Precision theranostics in nuclear medicine requires reproducible, calibrated quantificat...

OCTN1 variants shape innate immunity and predict individual response to anti-TNFα in ulcerative colitis patients: An exploratory study.

BACKGROUND: Ulcerative colitis (UC) exhibits substantial heterogeneity in inflammatory pathways and ...

Automated Eosinophil Quantification Using Deep Learning to Predict Therapy Escalation in Pediatric Ulcerative Colitis.

BACKGROUND: Emerging evidence implicates eosinophils as important modulators of disease activity and...

Antimycobacterial Peptides: From Natural Product Discovery to AI Guided Design.

Mycobacterial pathogens remain major global health threats, exacerbated by both rapid acquisition of...

Medicinal and Edible Plants for the Management of Inflammatory Bowel Disease: Synergistic Modulation of the Microbiota-Metabolite-Immune Axis.

Inflammatory bowel disease (IBD) is a chronic condition driven by the intertwined interplay of gut d...

Plasma multi-omics profiling unravels molecular alterations and biomarker panels during recovery from severe coronavirus disease 2019: a pilot study.

BACKGROUND: The potential multidimensional molecular alterations during recovery of severe patients ...

Artificial Intelligence in Colonoscopy Surveillance for Lynch Syndrome: Emerging Evidence, Lessons Learned From Average-Risk Populations, and Future Directions.

Lynch syndrome (LS) is the most common hereditary colorectal cancer (CRC) syndrome and is characteri...

Machine Learning Analysis of Serum Metabolomics for Multi-Disease Classification and Proteome-Metabolome Pathway Insights in T2D, IBD, and CRC.

Type 2 diabetes (T2D), inflammatory bowel disease (IBD), and colorectal cancer (CRC) share overlappi...

IL11⁺ fibroblasts are implicated in non-response to anti-TNFα via fibrosis in inflammatory bowel disease.

Inflammatory bowel disease (IBD) is frequently accompanied by intestinal fibrosis, with non-response...

Screening for Colorectal Cancer with Colonoscopy.

Colorectal cancer (CRC) imposes a substantial global burden, with highest incidence in Australia/New...

Calculation and evaluation of the effective withdrawal time of colonoscopy on the basis of internimage.

Flexible IMU Sensor Array For 3D Colonoscope Shape Reconstruction and AI-Based Loop Detection.

Looping during colonoscopy procedures is a major cause of patient discomfort and increases the risk ...

Delineating Pediatric Adrenocortical Tumors by GC-MS Urinary Steroid Metabolome Analysis: Observations From the MET Study.

INTRODUCTION: Adrenocortical tumors (ACTs) comprise adrenocortical adenomas (ACAs) and adrenocortica...

Graves' disease: a new era of pathophysiology-guided therapeutics.

Graves' disease (GD) is an autoimmune entity that had an unchanged treatment paradigm for more than ...

Colorectal cancer detection using noncontrast CT and deep learning: a multicenter and international cohort study.

BACKGROUND: Colorectal cancer (CRC) is a leading cause of cancer deaths, with early screening vital ...

From Time-Limited Therapy to Treatment-Free Observation: The Evolving Role of MRD in CLL Management.

The integration of measurable residual disease (MRD) into the management of chronic lymphocytic leuk...

Personalizing treatment of pancreatitis-associated chronic pain: the need for an integrated omics approach.

BACKGROUND: Chronic pancreatitis (CP) is a progressive inflammatory disorder characterized by debili...

Overcoming barriers to delivery of biologics by novel approaches and, advanced delivery systems.

Biologics is emerging as fastest growing field of drug development offering specificity and high the...

Inflammatory bowel disease burden in China and the United States from 1990-2023 and prediction to 2050.

BACKGROUND: Inflammatory bowel disease (IBD) shows divergent epidemiological trends in China and the...

Artificial allosteric protein switches with machine-learning-designed receptors.

Protein allostery underlies most information and energy processing in biology and the development of...

Identification and Validation of Transcriptomic Signatures in Inflammatory Bowel Disease with Metabolic Syndrome via Bioinformatics and Machine Learning.

BACKGROUND: Inflammatory bowel disease (IBD) is a chronic, nonspecific inflammatory disorder affecti...