Inflammatory Bowel Disease

PIBAdb: a public cohort of multimodal colonoscopy videos and images including polyps with histological information.

BACKGROUND AND OBJECTIVE: Colorectal cancer is the third most common cancer worldwide and presents a...

Precision immunotherapies for systemic lupus erythematosus: From pathogenic targets to translational horizons.

Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disorder in which aberrant B-cell a...

Dysbiosis of fecal virome in pediatric Crohn's disease and its dynamic changes during infliximab therapy.

UNLABELLED: The gut virome is an emerging but underexplored component of the human microbiota, espec...

Position Paper: IOlBD Evidence-based Consensus on the Use of Artificial Intelligence for Assessment of Endoscopic and Histologic Endpoints in Clinical Trials of Inflammatory Bowel Disease.

BACKGROUND & AIMS: Central reading of endoscopy and histopathology is the current standard for disea...

Noninvasive Blood-Based Detection of Endometriosis Can Improve Standard-of-Care by Facilitating Early Diagnosis and Clinical Management Among Symptomatic Women.

STUDY OBJECTIVE: To develop and validate a non-invasive, blood-based diagnostic assay for endometrio...

CAR T-cells in hematologic malignancies: Advances, challenges, and future directions.

Chimeric antigen receptor (CAR) T-cell therapy has transformed the management of hematologic maligna...

A Multiomic Liquid Biopsy for the Earlier Detection of Colorectal Cancer.

UNLABELLED: Timely diagnosis and intervention in colorectal cancer are critical to improving patient...

METRON: Metabolic Dynamic Perception Kolmogorov-Arnold Network for Biological Age Estimation.

Biological age provides a more direct reflection of physiological status than chronological age, ser...

Developing a Metabolic-Associated Prognostic Index for Risk Stratification and Therapeutic Guidance in Stage I Lung Adenocarcinoma via Multiomics Analysis.

PURPOSE: Early-stage lung adenocarcinoma (LUAD) exhibits substantial clinical heterogeneity that is ...

A Network-Based Association of IBD and Colorectal Cancer Using Proteomics Data.

BACKGROUND: Colorectal cancer (CRC) is a major cause of morbidity and mortality, with chronic inflam...

Artificial Intelligence for Predicting Clinical Outcomes in Interventional Pain Medicine for Spine Disorders: A Systematic Review.

OBJECTIVES: Artificial intelligence (AI) applications are being increasingly explored in pain medici...

Artificial Intelligence in FIT-Positive Colonoscopy: Balancing Detection Metrics and Clinical Impact.

Comparative urinary metabolomics reveals unique and shared pathways in COVID-19 and liver diseases.

INTRODUCTION: The COVID-19 pandemic and liver diseases both cause significant metabolic disturbances...

Computer-Aided Detection-Assisted Colonoscopy Teaches Gaze to Improve Adenoma Detection in First-Year Gastroenterology Fellows.

BACKGROUND AND AIMS: The impact of computer-aided detection (CADe)-assisted colonoscopy on gastroent...

Imputation methods for serologic biomarkers in inflammatory bowel disease.

Serologic biomarkers have emerged as a powerful tool for the diagnosis of Inflammatory Bowel Disease...

External Validation of an AI-Based Colonoscopy Quality Assessment Tool in Japanese Clinical Practice: A Pilot Study.

BACKGROUND: While AI-assisted polyp detection has advanced significantly, comprehensive AI-based col...

A peptide immunomodulator activates MST1 to expand and stabilize murine and human regulatory T cells for immune tolerance.

The expansion and potentiation of regulatory T cells (Treg cells) offer an appealing approach for ac...

Familial colorectal cancer: risk factors, screening strategies and personalized medicine.

Colorectal cancer (CRC) remains a leading cause of cancer-related mortality worldwide, with approxim...

Machine learning and metabolic signatures of drowning: A pathway to uncovering cause of death in aquatic environments.

The postmortem diagnosis of drowning is challenging due to the nonspecific and transient nature of c...

CT-derived sarcopenia and myosteatosis predict treatment escalation in hospitalized patients with inflammatory Bowel disease.

BACKGROUND: Sarcopenia and myosteatosis reflect muscle quantity and quality and are linked to advers...

Noninvasive diagnosis of colorectal adenoma: The emerging potential of blood-based biomarkers.

Colorectal cancer (CRC) is the third most commonly diagnosed cancer and the second leading cause of ...