Inflammatory Bowel Disease

Infrared spectroscopy with statistical analysis and machine learning for cancer risk assessment in inflammatory bowel disease patients.

Patients with inflammatory bowel disease (IBD) undergo regular colonoscopic surveillance due to thei...

Beyond the algorithm: what makes artificial intelligence-assisted colonoscopy effective in routine practice?

Future promise, current clinical ambiguity: a systematic review of machine learning algorithm outputs predicting risk of cardiovascular disease.

OBJECTIVE: To examine whether the outputs of machine learning algorithms designed to predict risk of...

Identification of COPZ1 as a Shared Candidate Ferroptosis-Related Hub Gene in Periodontitis and Inflammatory Bowel Disease.

Clinical and epidemiological evidence demonstrates a robust bidirectional link between inflammatory ...

UCResponNet-X: cross-platform multi-dataset gene expression for predictive modeling of drug response in ulcerative colitis.

Predictive modeling of biologic drug response using transcriptomic data is challenged by strong plat...

Machine Learning and Functional Analysis of Placental DNA Methylation Signatures for Early-Onset Preeclampsia.

Early-onset preeclampsia (EOPE) is a pregnancy disorder characterized by abnormal placental developm...

Comparative Efficacy of Different AI Systems for Polyp Detection by Size During Colonoscopy: Systematic Review and Network Meta-Analysis.

BACKGROUND: Colorectal cancer remains a leading cause of death despite being largely preventable thr...

Pan-cancer screening and integrative multi-omics and deep learning reveal the prognostic significance of an IBD-CRC shared host-microbe signature in bladder urothelial carcinoma.

BACKGROUND: The prognostic relevance of inflammatory bowel disease (IBD)-colorectal cancer (CRC) sha...

Stage-specific ROMO1 in rheumatoid arthritis: predictive immune insights into the MIF pathway and HLA-DR/IL2RA axis via integrated GWAS, transcriptomic, single-cell, and spatial profiling.

Emerging evidence links reactive oxygen species modulator 1 (ROMO1), a key mitochondrial ROS regulat...

The tire antioxidant derivative 6PPD-quinone exacerbates IBD by targeting NR1H4-mediated lipid metabolism and mitochondrial dysfunction in human colon epithelial cells.

N- (1,3-Dimethylbutyl)-N'-phenyl-p-phenylenediamine quinone (6PPD-Q), a tire rubber antioxidant deri...

AI Cautionary Guide: Pitfalls and Strategies for the Use of Machine Learning in Medical Research.

Machine learning (ML) is increasingly utilized in medical research. However, underrecognized methodo...

Internal validation of THINKERS-PA for outcome prediction after pituitary adenoma radiosurgery.

BACKGROUND: Outcome prediction after Gamma Knife radiosurgery (GKRS) for pituitary adenomas remains ...

Unsupervised machine learning with Cluster Analysis in patients with rheumatoid arthritis: insights in CV risk phenotypes from a multicentre Italian cohort.

Rheumatoid arthritis (RA) patients face increased cardiovascular (CV) risk, yet existing 10-year est...

Emotionally engaged speech reveals acoustic markers of depression and suicide risk.

BACKGROUND: Major depressive disorder exists along a continuum, from health through remission to act...

Feasibility of a Stool State Check App Using AI During Bowel Preparation Before Colonoscopy: Multicenter Prospective Study (SCAN Study).

BACKGROUND: Optimal bowel preparation (BP) is crucial for a successful colonoscopy. Although multipl...

New Evidence in Heart Failure: 2026 Update.

Heart failure (HF) remains a major cause of morbidity, mortality, impaired quality of life and healt...

Beyond maximum grade: key regulatory considerations in adverse event reporting.

The therapeutic landscape of haematological malignancies has evolved rapidly with the introduction o...

Comparison of artificial intelligence and multidisciplinary team assessment for evaluating biologic decisions in severe uncontrolled asthma.

BACKGROUND: The management of severe asthma with biologics has become more complex involving multidi...

Machine Learning-Driven Bioprospecting of Cholinergic Medicinal Plants for Putative Leads Against Butyrylcholinesterase Towards Alzheimer's Care.

Butyrylcholinesterase (BChE) plays a key role in preserving appropriate cholinergic neurotransmissio...

Machine learning provides individualized prediction of outcomes after first complete remission without allo-HSCT consolidation in adult acute myeloid leukemia-A HARMONY study.

Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a curative treatment option for a ...

Generative AI and Clinicians Show Comparable Prognostic Reasoning From Clinical Narratives in Biologic-Treated CRSwNP.

OBJECTIVE: To compare the ability of large language models (LLMs) and otolaryngologists to identify ...