Kidney Transplantation

Development of Machine Learning Models to Predict Hypoglycemia and Hyperglycemia on Days of Hemodialysis in Patients with Diabetes based on Continuous Glucose Monitoring

Patients with diabetes undergoing hemodialysis (HD) are at risk of asymptomatic hypo- and hypergly-cemia within 24 hours of dialysis. Continuous glucose monitoring (CGM) can improve glycemic control, and machine learning offers a promising approach to detect and predict glycemic excursions based on CGM data. This study aimed to develop machine learning models to predict substantial hypo- and hyper...

Early Identification of High-Risk Individuals for Mortality after Lung Transplantation: A Retrospective Cohort Study with Topological Transformers

Lung transplantation remains the only definitive treatment for patients with end-stage respiratory failure; however, it is burdened by a substantial risk of post-operative mortality. Current risk stratification methods, such as the Lung Transplant Risk Index, offer limited predictive performance and interpretability. This study introduces a novel predictive model based on topological transformers ...

Explainable machine learning on weighted connectivity networks across frequencies for outcome prediction in comatose patients

Accurate early prediction of neurological outcomes in comatose patients after cardiac arrest is critical for guiding therapeutic decisions and improvi...

Dynamic Lymphocyte Recovery Patterns Predict 90-Day Mortality in Sepsis: A Machine Learning-Enhanced Analysis of the MIMIC-IV Cohort

Sepsis-induced immunosuppression, characterized by lymphopenia, is associated with adverse outcomes. We aimed to identify distinct lymphocyte recovery...

Precision Immunosuppression and Long-Term Kidney Transplant Outcomes: A Dual Survival Modeling Framework

Optimizing immunosuppressive therapy remains central to improving long-term outcomes after kidney transplantation. Both induction and maintenance ther...

How should artificial intelligence be used in breast screening? Women's reasoning about workflow options.

Studies show that breast screening participants are open to artificial intelligence (AI) in breast screening, but hold concerns about AI performance, ...

Machine learning-based prediction models in medical decision-making in kidney disease: patient, caregiver, and clinician perspectives on trust and appropriate use.

OBJECTIVES: This study aims to improve the ethical use of machine learning (ML)-based clinical prediction models (CPMs) in shared decision-making for ...

Establishment and Validation of the Novel Necroptosis-related Genes for Predicting Stemness and Immunity of Hepatocellular Carcinoma Machine-learning Algorithm.

BACKGROUND: Necroptosis, a recently identified mechanism of programmed cell death, exerts significant influence on various aspects of cancer biology, ...

Bayesian-optimized deep learning for identifying essential genes of mitophagy and fostering therapies to combat drug resistance in human cancers.

Dysregulated mitophagy is essential for mitochondrial quality control within human cancers. However, identifying hub genes regulating mitophagy and de...

Formalization of Biological Circuit Block Diagrams for formally analyzing Biomedical Control Systems in pHRI Applications

The control of Biomedical Systems in Physical Human-Robot Interaction (pHRI) plays a pivotal role in achieving the desired behavior by ensuring the ...

Leveraging Cardiovascular Simulations for In-Vivo Prediction of Cardiac Biomarkers

Whole-body hemodynamics simulators, which model blood flow and pressure waveforms as functions of physiological parameters, are now essential tools ...

Context-Aware Outlier Rejection for Robust Multi-View 3D Tracking of Similar Small Birds in An Outdoor Aviary

This paper presents a novel approach for robust 3D tracking of multiple birds in an outdoor aviary using a multi-camera system. Our method addresses...

Re-calibrating methodologies in social media research: Challenge the visual, work with Speech

This article methodologically reflects on how social media scholars can effectively engage with speech-based data in their analyses. While contempor...

Predicting Survival of Hemodialysis Patients using Federated Learning

Hemodialysis patients who are on donor lists for kidney transplant may get misidentified, delaying their wait time. Thus, predicting their survival ...

Identification of novel M2 macrophage-related molecule ATP6V1E1 and its biological role in hepatocellular carcinoma based on machine learning algorithms.

Hepatocellular carcinoma (HCC) remains the most prevalent form of primary liver cancer, characterized by late detection and suboptimal response to cur...

Multicenter integration analysis of TRP channels revealed potential mechanisms of immunosuppressive microenvironment activation and identified a machine learning-derived signature for improving outcomes in gliomas.

AIM: This study aimed to explore the mechanisms of transient receptor potential (TRP) channels on the immune microenvironment and develop a TRP-relate...

Quantification of follicles in human ovarian tissue using image processing software and trained artificial intelligence†.

Cancer survival rates in prepubertal girls and young women have risen in recent decades due to increasingly efficient treatments. However, many such t...

Derivation and Experimental Performance of Standard and Novel Uncertainty Calibration Techniques.

To aid in the transparency of state-of-the-art machine learning models, there has been considerable research performed in uncertainty quantification (...

Understanding the Manufacturing Process of Lipid Nanoparticles for mRNA Delivery Using Machine Learning.

Lipid nanoparticles (LNPs), used for mRNA vaccines against severe acute respiratory syndrome coronavirus 2, protect mRNA and deliver it into cells, ma...

Antihypertensive prescribing patterns in non-dialysis dependent chronic kidney disease: Findings from the Salford Kidney Study.

BACKGROUND: Hypertension is commonly observed in patients living with chronic kidney disease (CKD). Finding an optimal treatment regime remains challe...