Latest AI and machine learning research in liver transplantation for healthcare professionals.
BACKGROUND & AIMS: Resmetirom, a thyroid hormone beta (THR-β) agonist, has been shown to improve metabolic dysfunction-associated steatohepatitis (MASH) and fibrosis in patients with non-cirrhotic MASH in a phase III serial liver biopsy study. In the phase III MAESTRO-NASH trial, the impact of resmetirom compared with placebo on histologic fibrosis features was evaluated using artificial intellige...
PURPOSE: Colorectal liver metastases (CRLM) are a leading cause of mortality in patients with colorectal cancer. While surgical resection is the standard curative option, most patients are ineligible. Consequently, cryoablation (CA) has emerged as a potential alternative. This review aims to summarise the technical characteristics, clinical outcomes, immunomodulatory effects, and current combinati...
Acute kidney injury (AKI) is a severe complication in patients with decompensated cirrhosis, associated with increased mortality. This study aimed to ...
INTRODUCTION: There is an unmet need for simple tools to predict development of hepatic decompensation among patients with compensated cirrhosis. We a...
The gut microbiota (GM) has emerged as a key modulator of cancer development and therapeutic response beyond the gastrointestinal tract. In extra-inte...
Autoimmune diseases encompass a broad spectrum of disorders in which self-reactive T and B cells breach immune tolerance and drive chronic tissue infl...
The origin recognition complex (ORC) is a DNA-binding complex composed of six subunits involved in DNA replication in cancer cells. The prognostic and...
Artificial Intelligence (AI) is transforming medicine, providing unprecedented opportunities to enhance diagnosis, prognosis, and treatment across all...
BACKGROUND: Intraoperative hypotension (IOH) is associated with increased postoperative morbidity and mortality. This prospective study evaluated the ...
BACKGROUND: The gut-liver axis plays a critical role in liver disease progression; however, how gut microbial ecology and function vary across disease...
The integration of artificial intelligence (AI) with nanotechnology is redefining therapeutic strategies in cancer immunotherapy and chemotherapy. The...
The hemodynamic status of the portal vein plays a crucial role in the identification, treatment, and prognostic prediction of complications associated...
The immunosuppressive tumor microenvironment (TME) and intrinsic heterogeneity of ovarian cancer (OC) are primary drivers of therapeutic resistance an...
BACKGROUND AND AIMS: Predicting overall survival (OS) in cirrhotic patients undergoing transjugular intrahepatic portosystemic shunt (TIPS) remains ch...
Artificial intelligence (AI) is increasingly recognized as a transformative force in the field of solid organ transplantation. From enhancing donor-re...
BACKGROUND: Individuals with chronic hepatitis B (CHB) may harbor occult yet significant liver pathology despite normal alanine aminotransferase (ALT)...
BACKGROUND: Immune checkpoint molecules are pivotal regulators of immune activation and tolerance, playing critical roles in cancer, autoimmunity, inf...
UNLABELLED: Perineural invasion (PNI) is an important pathologic feature of cervical cancer that is associated with poor prognosis and provides key in...
Hepatocellular carcinoma (HCC) remains a leading cause of cancer-related mortality worldwide, primarily due to its low immunogenicity and immunosuppre...