Transplantation

Liver Transplantation

Latest AI and machine learning research in liver transplantation for healthcare professionals.

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Classification models of HCV NS3 protease inhibitors based on support vector machine (SVM).

Inhibition of the hepatitis C virus (HCV) non-structural protein 3 (NS3) serine protease by molecule inhibitors is an attractive strategy for the treatment of hepatitis C. We built four classification models based on a dataset of 413 HCV NS3 protease inhibitors using support vector machine method. The best performing model obtains the best prediction performance for the test set with prediction ac...

Jan 1 2015 25410306

On the Origins of Hepatitis C Virus NS5B Polymerase Inhibitory Activity Using Machine Learning Approaches.

Inhibition of non-structural protein 5B (NS5B) represents an attractive strategy for the therapeutic treatment of hepatitis C virus (HCV). In this study, machine learning classifiers such as artificial neural network (ANN), support vector machine (SVM), random forest (RF) and decision tree (DT) analyses were used to classify 970 compounds based on their physicochemical properties, including quantu...

Jan 1 2015 25961524
CHARACTERISTICS OF HEPATITIS B VIRUS COINFECTION AMONG HIV-INFECTED PREGNANT WOMEN.

UNLABELLED: The similar routes of transmission for HIV and HBV place patients with either infection at greater risk for HIV/HBV co-infection.

Jan 1 2015 26793842
[A case report of hepatitis B virus reactivation in a hepatitis B core antibody-positive, hepatitis B surface antigen-negative hemodialysis patient].

Reactivation of the hepatitis B virus (HBV) has been reported in patients receiving immunosuppressive therapy or chemotherapy. We report a case of HBV...

Jan 1 2015 26817167
Establishment of hepatitis A vaccine (inactivated, non-adsorbed) BRP batches 2 and 3.

The current hepatitis A vaccine (HAV), inactivated, non-adsorbed, European Pharmacopoeia (Ph. Eur.) Biological Reference Preparation (BRP) is used for...

Jan 1 2015 26830162
Visfatin and TGF-Β1 in primary biliary cirrhosis and two other common liver diseases.

UNLABELLED: The aim of this study is to investigate plasma concentration of visfatin and transforming growth factor Β1 (TGF-Β1) in three groups of pat...

Jan 1 2015 26867120
[Maintenance therapy for chronic hepatitis C].

Therapy of chronic hepatitis C presently achieves 60% of sustained virological response, with clear on improvement of liver histology. Failure to erad...

Jan 1 2007 17965632
[Retreatment strategies for the patients with HCV infection].

Despite recent advances in the treatment of chronic hepatitis C, especially introduction of combined therapy with pegylated interferons with ribavirin...

Jan 1 2005 16190570
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