Latest AI and machine learning research in liver transplantation for healthcare professionals.
BACKGROUND: Identifying communities disproportionately affected by hepatitis C infection is essential for targeted prevention and resource allocation. This study aimed to identify zip code tabulation areas at elevated risk of hepatitis C infection in Los Angeles County and to identify area-level variables of importance in estimating hepatitis C infection rates. METHODS: This was an ecological cros...
Comprehensive quality control is essential for ensuring the efficacy and safety of traditional Chinese medicines (TCMs). However, current quality control methods of TCMs primarily focus on quantifiable indicators, neglect the variation of pharmacodynamic constituents across disease progression. This study aimed to develop a comprehensive pathogenesis-oriented quality control framework for TCMs, us...
Glioblastoma multiforme (GBM) represents the most aggressive primary brain tumor in adults, characterized by significant heterogeneity, rapid progress...
BACKGROUND: It is urgent to find novel non-invasive biomarkers that can accurately diagnose alcohol-associated liver disease (ALD). The objective of t...
Rapid diagnostic tests (RDTs) are key to disease surveillance, yet their interpretation remains challenging due to weak test lines and difficulties in...
Hepatitis B virus-associated hepatocellular carcinoma (HBV-HCC) is a heterogeneous malignancy with poor prognosis, necessitating refined classificatio...
Alcoholic hepatitis (AH) is an acute form of alcohol-associated liver disease with very few treatment options. Recent studies highlighted liver metabo...
The heterogeneity and immunosuppressive characteristics of the tumor microenvironment present significant challenges to traditional treatment strategi...
Gastric cancer (GC) remains a leading cause of cancer-related mortality worldwide, with therapeutic efficacy often hindered by late-stage diagnosis, c...
T-cell bispecific antibodies (TCBs), a specialized subclass of bispecific antibodies (BsAbs), are engineered to simultaneously engage T cells and tumo...
BACKGROUND: Diagnosing disseminated intravascular coagulation (DIC) in patients with chronic liver disease is challenging because cirrhosis-related he...
Cancer-associated fibroblasts (CAFs) are major stromal components of the tumor microenvironment (TME) and play diverse roles in gastrointestinal (GI) ...
BACKGROUND: Ammonia, which was traditionally regarded as a metabolic by-product, has more recently emerged as a crucial regulator of tumor metabolism ...
PURPOSE OF REVIEW: Asthma continues to pose a serious global health issue affecting billions of people and causing significant morbidity. It is immuno...
Hepatocellular carcinoma (HCC) still occurs in patients with hepatitis C who achieved sustained virologic response (SVR) after direct-acting antiviral...
BACKGROUND: Thyroid carcinoma (TC) presents a rising global incidence, with a subset of cases progressing aggressively despite standard therapies. The...
BACKGROUND: Acute myeloid leukemia (AML) remains a therapeutic challenge due to chemoresistance and immunosuppression. This study aimed to discover no...
BACKGROUND: Hepatocellular carcinoma (HCC) is a highly lethal malignancy with high recurrence and limited therapies. Microvascular invasion (MVI) is a...
BACKGROUND: Intrahepatic cholangiocarcinoma (ICC) is a highly aggressive subtype of primary liver cancer with insidious onset, early metastasis, and p...
BACKGROUND AND AIMS: Steatotic liver disease (SLD) has emerged as an important risk factor for hepatocellular carcinoma (HCC), often in the absence of...