Oncology/Hematology

Lung Cancer

Latest AI and machine learning research in lung cancer for healthcare professionals.

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Low-dose CBCT image reconstruction: a review.

Cone-beam computed tomography (CBCT) is a critical imaging modality in various medical fields, yet its repeated use poses radiation risks to patients. Low-dose CBCT image reconstruction aims to mitigate these risks while preserving image quality, which is crucial for clinical diagnosis and treatment. This review paper provides an in-depth analysis of the latest research progress in low-dose CBCT i...

Dec 5 2025 41348234

Morphologic Evaluation of Hyperchromatic Crowded Groups Present in Cervical Thin Prep Cytology Tests as Identified by the Hologic Genius Digital Diagnostics System: A Descriptive Study.

BACKGROUND: Our descriptive study focused on morphologic characteristics of hyperchromatic crowded groups (HCGs) in ThinPrep cervical cytology tests when reviewed with the artificial intelligence (AI)-assisted Hologic Genius Digital Diagnostics System (HGDDS). METHOD: After IRB approval, our archives were searched over a 1-year period for potential HCGs. A total of 157 slides with HCGs were select...

Dec 4 2025 41346093
Machine learning models for predicting response to epidermal growth factor receptor tyrosine kinase inhibitors in non-small cell lung cancer brain metastases: a systematic review and meta-analysis.

BACKGROUND: Predicting clinical and radiological outcomes of epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) in patients with ...

Dec 3 2025 41335187
Curcumin reprograms metabolic pathways and MAPK signaling to exert antidepressant effects.

BACKGROUND: Depression is a prevalent and debilitating mental disorder with limited treatment options. Curcumin, a natural compound with neuroprotecti...

Dec 3 2025 41438694
3D Automated Segmentation of Bronchial Abnormalities on Ultrashort Echo Time MRI: A Quantitative MR Outcome in Cystic Fibrosis.

BACKGROUND: Cystic fibrosis (CF) monitoring relies on computed tomography (CT), but ultra-short echo time MRI (UTE-MRI) offers a radiation-free altern...

Dec 2 2025 41328895
Development of a machine learning model for preoperative prediction of spread through air spaces in resectable non-small cell lung cancer: A single-center retrospective study.

Spread through air spaces (STAS) is a pathological feature associated with poor prognosis in non-small cell lung cancer (NSCLC). However, its diagnosi...

Dec 1 2025 41383980
Automated quality assurance of imaging dose and protocol adherence in computed tomography radiotherapy planning using TotalSegmentator-based segmentation.

PURPOSE: Computed tomography (CT) scans are vital for radiotherapy planning, providing essential data for dose calculations. This study retrospectivel...

Nov 28 2025 41313446
Three-dimensional surface scanning for registration in stereotactic neurosurgery: a cadaveric feasibility study.

OBJECTIVE: Achieving submillimetric accuracy in stereotactic neurosurgery remains critical for safely targeting deep brain structures. Current workflo...

Nov 28 2025 41343819
An Explainable Deep Model for Risk Scoring and Accurate Radionecrosis Identification Following Brain Metastasis Stereotactic Radiosurgery.

PURPOSE: As survival improves for patients with brain metastases (BM), distinguishing local recurrence (LR) from radionecrosis (RN) is a growing neuro...

Nov 27 2025 41317799
Artificial intelligence for TNM staging in NSCLC: a critical appraisal of segmentation utility in [1⁸F]FDG PET/CT.

PURPOSE: This study aims to investigate whether a diagnostic AI model can effectively support lesion detection and staging in non-small cell lung canc...

Nov 23 2025 41275455
A Comparative, Multiobserver Analysis of Nodal Contouring Methods in Pelvic Online Cone Beam-Based Adaptive Radiation Therapy.

PURPOSE: In online cone beam computed tomography (CBCT)-based adaptive radiation therapy (ART), nodal recontouring ensures sufficient nodal coverage b...

Nov 20 2025 41550204
Integrated multi-omics analyses identified the H3K18la-based spatiotemporal characteristics and risk-stratified treatment strategy in lung adenocarcinoma.

Lung adenocarcinoma (LUAD) is the most common histological type of lung cancer, characterized by high mortality, recurrence, and metastasis. Despite a...

Nov 20 2025 41274397
Accuracy of Photon Dose Calculation on Photon-Counting Computed Tomography-A Comparison Study Based on Virtual Monoenergetic and Electron Density (Rho) Images for Pancreatic Cases.

PURPOSE: Photon-counting computed tomography (PCCT) offers versatile anatomic information because of better energy discrimination and higher spatial r...

Nov 19 2025 41541756
Total-body [18F]FDG-PET/CT imaging of healthy volunteers with minimal effective dose.

PURPOSE: High-sensitivity, total-body (TB) positron emission tomography (PET) and computed tomography (CT) imaging systems enable substantial reductio...

Nov 18 2025 41251746
Hopfield neural networks with diverse activation functions: impact of variable action gradients and electromagnetic radiation effects.

Activation functions and their variable gradient action are pivotal in bridging artificial neural networks with the dynamic behavior of biological neu...

Nov 17 2025 41319405
Novel growth pattern-specific digital marker of TILs improves stratification of lung adenocarcinoma patients.

Lung adenocarcinoma (LUAD) is one of the most prevalent forms of cancer and continues to be associated with high mortality rates, despite recent advan...

Nov 15 2025 41240064
Emerging trends in nuclear medicine: breakthrough in radiopharmaceuticals, Geant4 simulations, and AI integration.

Nuclear medicine has witnessed revolutionary progress, spurred by advances in radiopharmaceuticals, computational modeling, and artificial intelligenc...

Nov 14 2025 41237411
Noninvasive follicular thyroid neoplasm with papillary-like nuclear features: an update.

PURPOSE OF REVIEW: Noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) has been recognized as a diagnostic entity sin...

Nov 10 2025 41213591
Automatic segmentation and CT-based deep learning radiomics nomogram for predicting overall survival in patients with small cell lung cancer: A multicenter cohort study.

BACKGROUND AND OBJECTIVE: Accurate prediction of overall survival (OS) in patients with small cell lung cancer (SCLC) is crucial for personalized trea...

Nov 10 2025 41252869
The Impact of Radiation Dose to Bowel on the Risk of Developing Gastrointestinal Toxicities When Treating Abdominopelvic Soft-Tissue Sarcomas With Preoperative Radiation Therapy.

PURPOSE: Abdominopelvic soft-tissue sarcomas (AP-STS) are selectively treated with radiation therapy (RT) followed by surgery. We investigated dosimet...

Nov 9 2025 41492444
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