Oncology/Hematology

Lung Cancer

Latest AI and machine learning research in lung cancer for healthcare professionals.

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Current State-of-the-Art 3D MRI Sequences for Assessing Bone Morphology with Emphasis on Cranial and Spinal Imaging: A Narrative Review.

Traditionally, CT has been the go-to method for visualizing bone structures, while MRI has been preferred for assessing soft tissues, because structures containing tightly bound water molecules - such as bones, tendons, cartilage, and ligaments - produce a rapidly decaying T2* signal, which conventional MRI sequences fail to capture. To address this limitation, spoiled gradient echo sequences were...

Sep 17 2025 40962128

Multimodal deep learning method based on multiple spectra for lung cancer early diagnosis.

Lung cancer remains one of the most lethal malignancies worldwide, and the early and accurate diagnostic is critical. Traditional diagnostic techniques such as imaging and histopathology often suffer from limitations including high cost, radiation exposure, and reliance on expert experience. In this study, a multimodal deep learning method based on multiple spectra is proposed for lung cancer dete...

Sep 12 2025 40957203
A Pilot Study on Quantitative Accuracy and Radiomic Feature Stability of Deep Progressive Learning Reconstruction in NSCLC PET.

Deep progressive learning reconstruction (DPR) is a novel deep learning-based algorithm for PET imaging, yet its impact on quantitative metrics and ra...

Sep 2 2025 40897832
Optimizing guideline-directed medical therapy in chronic kidney disease and type 2 diabetes mellitus patients in primary care.

BACKGROUND: Despite KDIGO (Kidney Disease: Improving Global Outcomes) recommendations for renin-angiotensin-aldosterone system inhibitors (RAASi's) an...

Sep 1 2025 40902917
Novel risk calculator predicting long-term survival in pediatric versus adult patients diagnosed with spinal low-grade glioma: a nationwide analysis.

BACKGROUND CONTEXT: Spinal low-grade gliomas (SLGGs) are rare, slow-growing central nervous system tumors affecting both pediatric and adult populatio...

Aug 28 2025 40885265
Screening for Barrett Esophagus and Esophageal Adenocarcinoma: Approaches and Outcomes.

Barrett esophagus (BE) is the only known histological precursor to esophageal adenocarcinoma (EAC). The incidence of EAC has risen significantly over ...

Aug 25 2025 40874980
Spatial imaging features derived from SUVmax location in resectable NSCLC are associated with tumor aggressiveness.

PURPOSE: Accurate non-invasive prediction of histopathologic invasiveness and recurrence risk remains a clinical challenge in resectable non-small cel...

Aug 21 2025 40839309
Determining the Survival Impact and Cost-Effectiveness of Multi-Gene Panel Sequencing in Metastatic Colorectal Cancer With Super Learning Approaches.

OBJECTIVE: To determine the effectiveness and cost-effectiveness of multi-gene panel sequencing compared to single-gene KRAS testing for metastatic co...

Aug 13 2025 40802545
PD-L1 expression scoring using artificial intelligence algorithms in non-small cell lung cancer harbouring ROS1 fusions: potential clinical-biological significance.

BACKGROUND: PD-L1 expression in ROS1-positive non-small cell lung carcinoma (NSCLC) patients remains unclear regarding its possible clinical-biologica...

Aug 11 2025 40790287
Development and validation of a transformer-based deep learning model for predicting distant metastasis in non-small cell lung cancer using 18FDG PET/CT images.

BACKGROUND: This study aimed to develop and validate a hybrid deep learning (DL) model that integrates convolutional neural network (CNN) and vision t...

Aug 8 2025 40779149
Machine learning modeling and analysis of prognostic hub genes in cervical adenocarcinoma: a multi target therapy for enhancement in immunosurveillance.

Endocervical adenocarcinoma (ECA) the fatal and intrusive subtype of cervical carcinoma is on rise from the last decade. Its improper detection leads ...

Jul 13 2025 40653567
Machine learning analysis of survival outcomes in breast cancer patients treated with chemotherapy, hormone therapy, surgery, and radiotherapy.

Breast cancer continues to be a leading cause of death among women in the world. The prediction of survival outcomes based on treatment modalities, i....

Jul 10 2025 40640463
Non-invasive identification of TKI-resistant NSCLC: a multi-model AI approach for predicting EGFR/TP53 co-mutations.

OBJECTIVES: To investigate the value of multi-model based on preoperative CT scans in predicting EGFR/TP53 co-mutation status.

Jul 10 2025 40640822
AI Revolution in Radiology, Radiation Oncology and Nuclear Medicine: Transforming and Innovating the Radiological Sciences.

The integration of artificial intelligence (AI) into clinical practice, particularly within radiology, nuclear medicine and radiation oncology, is tra...

Jul 9 2025 40631621
Radiomics in Early Detection of Pancreatic Ductal Adenocarcinoma: A Close Look at Its Current Status and Challenges to Clinical Implementation.

Radiomics is a mathematical approach to medical images to extract quantitative features generating a "radiomics signature." The radiomics workflow inv...

Jul 9 2025 40632579
Machine learning for synchronous bone metastasis risk prediction in high grade lung neuroendocrine carcinoma.

Bone metastasis (BM) is common in high-grade lung neuroendocrine tumors (NETs). This study aimed to use multiple machine learning algorithms to explor...

Jul 9 2025 40634407
Real-world deployment of a fine-tuned pathology foundation model for lung cancer biomarker detection.

Artificial intelligence models using digital histopathology slides stained with hematoxylin and eosin offer promising, tissue-preserving diagnostic to...

Jul 9 2025 40634781
Deep Learning-Based Classification of NSCLC-Derived Extracellular Vesicles Using AFM Nanomechanical Signatures.

Nonsmall cell lung cancer (NSCLC) remains a leading cause of cancer-related mortality, with liquid biopsy emerging as a promising tool for noninvasive...

Jul 8 2025 40626500
Metabolic alterations driven by LDHA in CD8 + T cells promote immune evasion and therapy resistance in NSCLC.

Non-small cell lung cancer (NSCLC) is a leading cause of cancer-related deaths worldwide. Despite advancements in treatment, prognosis for patients wi...

Jul 8 2025 40629035
Machine learning assists regulated cell death crucial biomarker selection in adenocarcinoma of the lung: biological data testing and cell assay determination.

BACKGROUND: Lung cancer is a highly aggressive and lethal cancer requiring prognostic and predictive biomarkers for improving patient outcomes. Here, ...

Jul 8 2025 40629109
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