Lupus

Iatrogenic Cushing's syndrome as a consequence of nasal use of Betamethasone spray during pregnancy.

INTRODUCTION: Glucocorticoids (GC) are largely used for their anti-inflammatory and immunosuppressive effects. Until recently "local" administration (inhalation, topical, intra-articular, ocular and nasal) was considered devoid of important systemic side effects, but there is no administration form, dosing or treatment duration for which the risk of iatrogenic Cushing's syndrome (CS) and consequen...

FRENCH MARIGOLD (TAGETES PATULA L.) FLOWER EXTRACT PROTECTS KIDNEY CELLS FROM INFLAMMATION IN VITRO.

The aim of our study is to evaluate the mechanisms of anti-inflammatory property of Tagetes patula L. (French Marigold) flower extracts and its protective effect on renal epithelium against uropathogenic E. coli infection. Thus, in this study, a number of in vitro assays were performed to evaluate the antioxidant and anti-inflammatory activities of Tagetes patula L flower extract (water soluble pa...

Antiproliferative Activity of , , and in Interaction with the Prostatic Activity of CD82.

BACKGROUND: In recent years, prostate cancer prevails as one of the lead cancers affecting men. Currently, prostate cancer research involves the phyto...

Artificial Intelligence Estimates the Importance of Baseline Factors in Predicting Response to Anti-PD1 in Metastatic Melanoma.

OBJECTIVE: Prognosis of patients with metastatic melanoma has dramatically improved over recent years because of the advent of antibodies targeting pr...

High-throughput screening and Bayesian machine learning for copper-dependent inhibitors of Staphylococcus aureus.

One potential source of new antibacterials is through probing existing chemical libraries for copper-dependent inhibitors (CDIs), i.e., molecules with...

Virtual Screening of Anti-Cancer Compounds: Application of Monte Carlo Technique.

Possibility and necessity of standardization of predictive models for anti-cancer activity are discussed. The hypothesis about rationality of common q...

Automated and flexible identification of complex disease: building a model for systemic lupus erythematosus using noisy labeling.

UNLABELLED: Accurate and efficient identification of complex chronic conditions in the electronic health record (EHR) is an important but challenging ...

Identification of Anti-cancer Peptides Based on Multi-classifier System.

AIMS AND OBJECTIVE: Cancer is one of the deadliest diseases, taking the lives of millions every year. Traditional methods of treating cancer are expen...

Anti- Activity of Extracts from Argentinean Asteraceae Species.

The anti- activity of extracts from 13 Argentinean Asteraceae species was determined. Dichloromethane and methanol extracts of , , and were evaluated...

Effects of Baneh () Gum on Human Breast Cancer Cell Line (MCF-7) and Its Interaction with Anticancer Drug Doxorubicin.

is one of the species of that grows in the wild in different regions of Iran. Traditionally, family has antibacterial, fungicidal, and cytotoxic pr...

Anti-cancer Potential of Captopril and Botulinum Toxin Type-A and Associated p53 Gene Apototic Stimulating Activity.

Mutational inactivation of p53 is a key player in the development of human cancer. Thus, retrieving the tumor suppressor activity of p53 gene is consi...

Effect of Amino Acid Substitutions on Biological Activity of Antimicrobial Peptide: Design, Recombinant Production, and Biological Activity.

Recently, antimicrobial peptides have been introduced as potent antibiotics with a wide range of antimicrobial activities. They have also exhibited ot...

[Cerebral cryptococcosis and immune reconstitution inflammatory syndrome. Case report].

We report a 45-year-old male with AIDS who had a Cryptococcus neoformans central nervous system infection. He was treated with amphotericin B deoxycho...

In Vitro Investigation of Potential Anti-Diabetic Activity of the Corm Extract of Hypoxis Argentea Harv. Ex Baker.

The corms of Hypoxis argentea are widely used as a traditional remedy for diabetes mellitus in South Africa. In this study, we investigated the effect...

Clinical observation of the efficacy of low-molecular-weight heparin calcium in prophylaxis of the deep venous thrombosis following the gynecological tumor surgery.

Present study is conducted to investigate the efficacy and safety of application of low-molecular-weight heparin calcium in the prophylaxis of deep ve...

[Antidiabetic role of high density lipoproteins].

Disturbance in lipid metabolism can be both a cause and a consequence of the development of diabetes mellitus (DM). One of the most informative indica...

Impedance Model of the Interaction Between Environment and Human Body and Its Modification Design.

This paper presents a model of environment-human body interaction, which is critical for us to perform balanced motions such as locomotion and activit...

Computational Identification of Chemical Compounds with Potential Activity against Leishmania amazonensis using Nonlinear Machine Learning Techniques.

Leishmaniasis is a poverty-related disease endemic in 98 countries worldwide, with morbidity and mortality increasing daily. All currently used first-...

Immunomodulation of Zerumbone via Decreasing the Production of Reactive Oxygen Species from Immune Cells.

BACKGROUND AND OBJECTIVE: Zerumbone has been reported to exert anti-inflammatory, anti-ulcer and anti-hyperglycemic effects but the specific mechanism...

[Actinomyces with anti-candida activity isolated from leaf-cutting ants Atta cephalotes (Formicidae: Myrmicinae: Attini)].

OBJECTIVES.: To isolate, select and identify actinomyces associated to leaf-cutting ants Atta cephalotes (Linnaeus, 1758), that present a greater anti...