Latest AI and machine learning research in menopause for healthcare professionals.
Background Pretreatment prediction of primary resistance to anti-PD-(L)1 therapy in advanced non-small-cell lung cancer (NSCLC) remains an unmet clinical need. Existing biomarkers - including PD-L1 expression and tumour mutational burden (TMB) - are insufficiently discriminatory, and multimodal predictive models targeting primary resistance are still lacking to precisely drive patients treatment s...
Background: Cardiac resynchronization therapy (CRT) fails in 30% of patients, often due to suboptimal left ventricular pacing site (LVPS) selection. Current practice lacks tools for pre-procedural, patient-specific LVPS optimization within the accessible coronary sinus (CS) tributaries. This study aimed to develop a digital twin and an explainable ML-based clinical decision support framework to ad...
Background Endometriosis is a complex, estrogen-dependent disease with a strong genetic component. Although genome-wide association studies (GWAS) hav...
Visual generative models are typically trained in two stages. A tokenizer is first trained for reconstruction and then frozen, after which a generator...
Purpose: To evaluate the feasibility and challenges of heart chamber segmentation from non-contrast CT scans using contrastive unpaired image translat...
Accurate identification of the epileptogenic zone (EZ) is essential for seizure freedom after resective surgery in drug-resistant epilepsy, yet seizur...
Purpose: Prior authorization (PA) for exome or genome sequencing is a time-consuming process that impedes timely rare disease diagnosis. Large languag...
Kidney-function assessment relies on blood urea as a clinically informative metabolic marker; however, its dependence on venipuncture and centralised ...
Importance. Large language models (LLMs) increasingly inform mental health decisions by patients and clinicians. Inference-time activation steering ca...
Metastatic breast cancer is one of the leading causes of premature mortality among women worldwide. A major barrier to optimal care is the marked hete...
Sampling from high-dimensional, non-log-concave distributions with unnormalized densities is a fundamental challenge in machine learning, particularly...
Pairwise comparison is the gold standard for subjective ranking tasks; however, exhaustive annotation requires a massive number of human comparisons (...
Antimicrobial resistance (AMR) creates an urgent need for efficient strategies to identify effective antibacterial combinations. Combination therapy, ...
Circulating-tumour DNA (ctDNA) carries evidence of drug resistance months before imaging shows it, but the earliest evidence lives below the assay's l...
General-purpose large language models (LLMs) are routinely used as baselines when evaluating specialized pathology models on whole-slide images (WSIs)...
Camera traps have become a cornerstone of biodiversity monitoring, but the artificial intelligence that turns vast quantities of images into usable ec...
Peptide therapeutics are increasingly used to treat challenging diseases, but immunogenicity risks limit their clinical success. In silico tools enabl...
Multi-Modal Diffusion Transformers (MM-DiTs) encode rich representations for training-free concept grounding, but existing attention-based methods oft...
Wearable sensing technology capable of point-of-care, continuous and non-invasive analysis of exosomes in biofluid such as tears and sweat is an essen...
Bone marrow adiposity changes radically through the lifespan, but this phenomenon is poorly characterised and understood in humans. Large datasets of ...